[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566081":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":35,"centralContacts":36,"locations":42,"responsibleParty":60,"collaborators":35,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":35,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":35,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":87,"whyStopped":35,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Peking University Third Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Levofloxacin Plus Metronidazole Suppositories group","EXPERIMENTAL","Clinical pregnancy outcomes of the first embryo transfer in patients with chronic endometritis treated with Levofloxacin Plus Metronidazole Suppositories.",[13],"Drug: Levofloxacin Plus Metronidazole Suppositories",{"label":15,"type":16,"description":17,"interventionNames":18},"Levofloxacin co-administered with Metronidazole tablets group","ACTIVE_COMPARATOR","Clinical pregnancy outcomes after the first embryo transfer in patients with chronic endometritis treated with Levofloxacin co-administered with Metronidazole tablets.",[19],"Biological: Levofloxacin co-administered with Metronidazole tablets",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Levofloxacin Plus Metronidazole Suppositories","Administer a two-week course of Levofloxacin Plus Metronidazole Suppositories to patients diagnosed with chronic endometritis.",[9],[27],"Experimental",{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"BIOLOGICAL","Levofloxacin co-administered with Metronidazole tablets","Administer a two-week course of Levofloxacin in combination with Metronidazole tablets to patients diagnosed with chronic endometritis.",[15],[34],"Active Comparator",null,[37],{"name":38,"role":39,"phone":40,"phoneExt":35,"email":41},"Ming Mei Lin, MD","CONTACT","18500196527","linmingmei2023@163.com",[43],{"facility":44,"status":35,"city":45,"state":35,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Peking university third hospital","Beijing","100191","China","CN",{"type":50,"coordinates":51},"Point",[52,53],116.39723,39.9075,{"lat":53,"lon":52},[56],{"name":57,"role":39,"phone":58,"phoneExt":35,"email":59},"Kai Lun Hu, MD","15901575271","hukailun@bjmu.edu.cn",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"PRINCIPAL_INVESTIGATOR","Lin MingMei","Professor","100566081","levofloxacin-plus-metronidazole-suppositories-versus-levofloxacin-co-administered-with-metronidazole-tablets-in-chronic-endometritis-100566081",false,"NCT06650540","Levofloxacin Plus Metronidazole Suppositories Versus Levofloxacin Co-administered with Metronidazole Tablets in Chronic Endometritis","Levofloxacin Plus Metronidazole Suppositories Versus Levofloxacin Co-administered with Metronidazole Tablets for the Treatment of Chronic Endometritis: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Infertile patients aged 20-42 years\n* Hysteroscopy and endometrial biopsy were performed, and the\n* Pathological diagnosis was chronic endometritis\n* Serum FSH level on the second day of menstruation was ≤12U\u002FL\n* Agree and sign the informed consent form\n\nExclusion Criteria:\n\n* Patients with the following diagnoses: submucosal myoma; Uterine malformation or previous surgery for correction of uterine deformity; Intrauterine adhesions; The previous history of pelvic tuberculosis or endometrial tuberculosis or the current pathology suggested endometrial tuberculosis; Endometrial hyperplasia or endometrial cancer\n* Patients with spouse, previous fetal or child chromosomal abnormalities who plan to undergo preimplantation genetic screening\n* Patients with a history of allergy to study drugs","FEMALE","20 Years","42 Years",{"count":75,"type":76},800,"ESTIMATED","INTERVENTIONAL",[79],"NA","This is a single randomised controlled trial. The investigators plan to randomise 800 participants to the levofloxacin plus metronidazole suppositories versus levofloxacin co-administered with metronidazole tablets for the treatment of chronic endometritis in a 1:1 rate. Primary outcome will be the live birth rate after the embryo transfer.",[82],"IVF",[84,85,86],"Chronic Endometritis","pregnancy outcomes","pharmacological treatment","NOT_YET_RECRUITING","2024-10-18",{"date":90,"type":91},"2024-10-21","ACTUAL",{"date":93,"type":76},"2024-10-22",{"date":95,"type":76},"2026-12-30",{"name":5,"class":6},1]