[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100620587":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":46,"centralContacts":51,"locations":59,"responsibleParty":74,"collaborators":38,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":38,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":99,"overallStatus":104,"whyStopped":38,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Zagazig University","OTHER_GOV",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm 1: Control Group (Normal Saline)","PLACEBO_COMPARATOR","Participants in this arm will receive 15 mL of 0.9% normal saline intravenously over 15 minutes, starting 30 minutes before the anticipated time of extubation. This serves as the control intervention for comparison with lidocaine and magnesium sulfate.",[13],"Drug: Normal Saline (Intravenous)",{"label":15,"type":16,"description":17,"interventionNames":18},"Arm 2: Lidocaine Group","EXPERIMENTAL","Participants in this arm will receive intravenous lidocaine at a dose of 1.5 mg\u002Fkg diluted with 0.9% normal saline to a total volume of 15 mL. The infusion will be administered over 15 minutes, starting 30 minutes before the expected time of extubation.",[19],"Drug: Lidocaine (drug)",{"label":21,"type":16,"description":22,"interventionNames":23},"Arm 3: Magnesium Sulfate Group","Participants in this arm will receive intravenous magnesium sulfate at a dose of 30 mg\u002Fkg diluted with 0.9% normal saline to a total volume of 15 mL. The infusion will be administered over 15 minutes, starting 30 minutes before the anticipated time of extubation.",[24],"Drug: magnesium sulfate",[26,34,39,42],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","Lidocaine (drug)","The intervention described in this clinical study involves a comparative prospective randomized double-blind controlled trial to assess the effects of intravenous Lidocaine versus Magnesium Sulfate compared to a Control group for hemodynamic stability during emergence from general anesthesia in infertility-related laparoscopic gynecologic surgeries.",[15],[32,33],"magnisium sulfate","saline",{"type":27,"name":35,"description":36,"armGroupLabels":37,"otherNames":38},"Normal Saline (Intravenous)","0.9% normal saline, total volume 15 mL, administered intravenously over 15 minutes starting 30 minutes before the anticipated time of extubation.",[9],null,{"type":27,"name":28,"description":40,"armGroupLabels":41,"otherNames":38},"Lidocaine 1.5 mg\u002Fkg diluted with 0.9% normal saline to a total volume of 15 mL, administered intravenously over 15 minutes starting 30 minutes before the anticipated time of extubation.",[15],{"type":27,"name":43,"description":44,"armGroupLabels":45,"otherNames":38},"magnesium sulfate","Magnesium sulfate 30 mg\u002Fkg diluted with 0.9% normal saline to a total volume of 15 mL, administered intravenously over 15 minutes starting 30 minutes before the anticipated time of extubation.",[21],[47],{"name":48,"affiliation":49,"role":50},"Amira S Kenawy, lecturer","Zagazig University Hospitals, Zagazig University","PRINCIPAL_INVESTIGATOR",[52,57],{"name":53,"role":54,"phone":55,"phoneExt":38,"email":56},"Amira S principal investigator, lecturer","CONTACT","01092014663","IRB_123@medicine.zu.edu.eg",{"name":48,"role":54,"phone":55,"phoneExt":38,"email":58},"amira9981@gmail.com",[60],{"facility":61,"status":38,"city":62,"state":38,"zip":38,"country":63,"countryCode":64,"cosmosGeoPoint":65,"geoPoint":70,"contacts":71},"Zagazig University Faculty of Medicine","Zagazig","Egypt","EG",{"type":66,"coordinates":67},"Point",[68,69],31.502,30.58768,{"lat":69,"lon":68},[72],{"name":73,"role":54,"phone":55,"phoneExt":38,"email":58},"Amira s Kenawy, lecturer",{"type":50,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":38,"oldOrganization":38},"Amira S kenawy ,md","Lecturer of Anesthesia, Intensive Care, and Pain Management","100620587","lidocaine-vs-magnesium-sulfate-for-hemodynamic-stability-during-emergence-in-infertility-related-laparoscopic-surgery-100620587",false,"NCT07359560","Lidocaine vs Magnesium Sulfate for Hemodynamic Stability During Emergence in Infertility-Related Laparoscopic Surgery\"","Intravenous Lidocaine Versus Magnesium Sulfate for Hemodynamic Stability During Emergence From General Anesthesia in Infertility-related Laparoscopic Gynecologic Surgeries","LidoMagGyna","Inclusion Criteria:\n\nFemale patients aged 21 to 40 years\n\nBody mass index (BMI) between 18.5 and 29 kg\u002Fm²\n\nAmerican Society of Anesthesiologists (ASA) physical status I or II\n\nScheduled for elective infertility-related laparoscopic gynecologic surgery (e.g., diagnostic laparoscopy, ovarian cystectomy, adhesiolysis) under general anesthesia\n\nExpected duration of anesthesia less than 2 hours\n\nAbility to provide written informed consent\n\nExclusion Criteria:\n\nKnown allergy or contraindication to lidocaine or magnesium sulfate\n\nHistory of significant cardiac, renal, or hepatic disease\n\nChronic use of analgesics or history of drug dependence\n\nHistory of myasthenia gravis\n\nPregnancy or positive serum β-hCG test\n\n\\-",true,"FEMALE","21 Years","40 Years",{"count":90,"type":91},69,"ESTIMATED","INTERVENTIONAL",[94],"NA","This study is being conducted to compare two medications, intravenous lidocaine and intravenous magnesium sulfate, and their ability to keep blood pressure and heart rate stable during the period of waking up from general anesthesia in infertility-related laparoscopic gynecologic surgeries.\n\nLaparoscopic gynecologic procedures can cause changes in heart rate and blood pressure, especially during emergence from anesthesia, and these changes may affect patient safety.\n\nIn this randomized, double-blind clinical trial, women scheduled for elective infertility-related laparoscopic surgery will be assigned to one of three groups: lidocaine, magnesium sulfate, or a control group. The study will evaluate mean arterial pressure (primary outcome), heart rate, pain scores, sedation level, nausea and vomiting, and any side effects during and after surgery.\n\nThe goal is to determine which medication provides better hemodynamic stability and improves recovery in the early postoperative period.",[97,98],"Infertility Female","Hemodynamic Instability",[100,101,102,103],"lidocaine magnisium","hemodynamic instability","infertility female","laparoscopic surgery","NOT_YET_RECRUITING","2026-01-13",{"date":107,"type":108},"2026-01-22","ACTUAL",{"date":110,"type":91},"2026-01-02",{"date":112,"type":91},"2026-07-02",{"name":5,"class":6},1]