[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628778":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":34,"responsibleParty":51,"collaborators":18,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":18,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":18,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":77,"overallStatus":37,"whyStopped":18,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"University of Sao Paulo","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TransForm Health group","EXPERIMENTAL","A group intervention focused on promoting health lifestyle behaviors for preventing obesity and eating disorders in transgender and gender-diverse adolescents.",[13],"Behavioral: TransForm Health Program",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","Usual care and general health lifestyle behaviors recommendations.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","TransForm Health Program","A 6-month structured intervention including monthly adolescent group sessions, monthly caregiver sessions, monthly individual goal-setting meetings, and weekly reinforcement messages focused on healthy eating, physical activity, body appreciation, and prevention of unhealthy weight-control behaviors.",[9],[26,31],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Bruno Gualano, PhD","CONTACT","+551130618789","gualano@usp.br",{"name":32,"role":28,"phone":18,"phoneExt":18,"email":33},"Bruna Caruso Mazzolani, PhD","bruna.mazzolani@usp.br",[35],{"facility":36,"status":37,"city":38,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo","RECRUITING","São Paulo","05403010","Brazil","BR",{"type":43,"coordinates":44},"Point",[45,46],-46.63611,-23.5475,{"lat":46,"lon":45},[49],{"name":27,"role":28,"phone":50,"phoneExt":18,"email":30},"+551126618022",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Bruno Gualano","Professor","100628778","lifestyle-intervention-for-obesity-and-eating-disorder-prevention-in-transgender-adolescents-100628778",false,"NCT07466069","Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents","Lifestyle Intervention to Prevent Obesity and Eating Disorders in Transgender and Gender-Diverse Adolescents: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 10-14 years\n* Self-identified as transgender or gender-diverse\n\nExclusion Criteria:\n\n* Current diagnosis of eating disorder requiring specialized treatment\n* Severe psychiatric instability\n* Cognitive impairment limiting participation","ALL","10 Years","14 Years",{"count":66,"type":67},24,"ESTIMATED","INTERVENTIONAL",[70],"NA","Transgender and gender-diverse adolescents are at increased risk for obesity, disordered eating behaviors, body dissatisfaction, and reduced quality of life due to minority stress and structural inequities. However, no structured lifestyle interventions specifically tailored to this population have been developed.\n\nThis randomized controlled trial aims to evaluate the effectiveness of a 6-month interdisciplinary lifestyle intervention designed to prevent obesity and eating disorders in transgender and gender-diverse adolescents aged 10-14 years. Participants will be randomized (1:1) to either an intervention group receiving monthly group sessions (for adolescents and caregivers separately) and weekly supportive messages, or a control group receiving standard outpatient care and general health recommendations.\n\nThe primary outcome is quality of life measured by the WHOQOL-BREF. Secondary outcomes include eating disorder symptoms, body image, diet quality, physical activity levels, sedentary behavior, body composition, and anthropometric measures.",[73,74,75,76],"Obesity & Overweight","Eating Disorders","Body Image Disturbance","Gender Diverse Populations",[78,79,80,81,82,83],"Transgender","Adolescent","Gender-diverse","Lifestyle","Eating disorders","Obesity","2026-03-06",{"date":86,"type":87},"2026-03-12","ACTUAL",{"date":89,"type":67},"2026-03",{"date":91,"type":67},"2026-12",{"name":5,"class":6},1]