[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100456545":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":30,"locations":39,"responsibleParty":61,"collaborators":63,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":12,"eligibilityCriteria":75,"healthyVolunteers":72,"sex":76,"minAge":77,"maxAge":12,"enrollmentInfo":78,"targetDuration":12,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":12,"overallStatus":42,"whyStopped":12,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Columbia University","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Variable Schedule","NO_INTERVENTION","Participants randomized to Variable Schedule (VS) will be asked to maintain their usual habits for 12 weeks.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Fixed Schedule","EXPERIMENTAL","Participants randomized to Fixed Schedule (FS) will be asked to stabilize their lifestyle behaviors for 12 weeks.",[18],"Behavioral: Fixed Schedule",[20],{"type":21,"name":14,"description":22,"armGroupLabels":23,"otherNames":12},"BEHAVIORAL","Participants will be asked to maintain a fixed schedule for 12 weeks.",[14],[25,28],{"name":26,"affiliation":5,"role":27},"Marie-Pierre St-Onge","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":5,"role":27},"Blandine Laferrere",[31,35],{"name":26,"role":32,"phone":33,"phoneExt":12,"email":34},"CONTACT","212-851-5578","ms2554@cumc.columbia.edu",{"name":36,"role":32,"phone":37,"phoneExt":12,"email":38},"Lena Navarro","347-963-8845","lrn2116@cumc.columbia.edu",[40],{"facility":41,"status":42,"city":43,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Columbia University Irving Medical Center","RECRUITING","New York","10032","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-74.00597,40.71427,{"lat":51,"lon":50},[54,56,60],{"name":55,"role":32,"phone":12,"phoneExt":12,"email":34},"Marie-Pierre St-Onge, PhD",{"name":57,"role":32,"phone":58,"phoneExt":12,"email":59},"Lara Bond","9175814637","lsb2173@cumc.columbia.edu",{"name":26,"role":27,"phone":12,"phoneExt":12,"email":12},{"type":27,"investigatorFullName":26,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Associate Professor of Nutritional Medicine",[64,67],{"name":65,"class":66},"Department of Health and Human Services","FED",{"name":68,"class":69},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH","100456545","lifestyle-patterns-and-glycemic-control-100456545",false,"NCT05224986","Lifestyle Patterns and Glycemic Control","Inclusion Criteria:\n\n* Pre-diabetic kg\u002Fm2 (hemoglobin A1c 5.7-6.9%)\n* 25 years or older\n* BMI between 25-39.9 kg\u002Fm2\n* Sleep duration ≥6 hours a night assessed with wrist actigraphy (for 14 nights)\n* Variable bedtime, SD≥45 minutes.\n\nExclusion Criteria:\n\n* Chronic Kidney Disease (GFR\\\u003C60)\n* Uncontrolled hypertension (≥160\u002F100 mmHg)\n* Obstructive Sleep Apnea\n* Psychiatric or neurological disorder\n* Prevalent cardiovascular disease\n* Dyslipidemia (triglycerides≥200 mg\u002FdL)\n* Medications that affect insulin sensitivity, glucose concentrations, and body weight\n* Non-day or rotating shift workers\n* Travel across time zones\n* Active participation in weight loss program or within past 3 months\n* Current or past alcohol\u002Fdrug abuse","ALL","25 Years",{"count":79,"type":80},34,"ESTIMATED","INTERVENTIONAL",[83],"NA","The goal of the proposed study is to evaluate the feasibility and initial efficacy of stabilizing lifestyle behaviors to improve glucose control and body composition in patients with pre-diabetes.\n\nThe investigator proposes that following stable lifestyle behaviors will improve patients' glucose control, body composition, and liver fat. The results from this study has the potential to impact clinical practice and patient care.",[86],"Pre-diabetes","2026-01-27",{"date":89,"type":90},"2026-01-28","ACTUAL",{"date":92,"type":90},"2022-01-19",{"date":94,"type":80},"2026-07-31",{"name":5,"class":6},1]