[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100450932":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":35,"centralContacts":39,"locations":47,"responsibleParty":91,"collaborators":26,"id":94,"slug":95,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":100,"eligibilityCriteria":101,"healthyVolunteers":96,"sex":102,"minAge":103,"maxAge":104,"enrollmentInfo":105,"targetDuration":26,"studyType":108,"phases":109,"briefSummary":111,"conditions":112,"keywords":114,"overallStatus":67,"whyStopped":26,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":126},{"fullName":5,"class":6},"Tampere University Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Full weight-bearing","EXPERIMENTAL","Full immediate weight-bearing postoperatively",[13,14],"Procedure: Full weight-bearing","Procedure: Intramedullary nailing",{"label":16,"type":17,"description":18,"interventionNames":19},"Partial-weight bearing","ACTIVE_COMPARATOR","Partial weight-bearing for the first 6 weeks postoperatively.",[20,14],"Procedure: Partial weight-bearing",[22,27,31],{"type":23,"name":9,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Instruction for full and immediate weight-bearing postoperatively",[9],null,{"type":23,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Partial weight-bearing","Instruction for partial weight-bearing for 6 weeks postoperatively",[16],{"type":23,"name":32,"description":33,"armGroupLabels":34,"otherNames":26},"Intramedullary nailing","Intramedullary nailing of the fractured tibial shaft.",[9,16],[36],{"name":37,"affiliation":5,"role":38},"Aleksi Reito, Assoc prof","PRINCIPAL_INVESTIGATOR",[40,44],{"name":37,"role":41,"phone":42,"phoneExt":26,"email":43},"CONTACT","+358444729631","aleksi.reito@pshp.fi",{"name":45,"role":41,"phone":26,"phoneExt":26,"email":46},"Satu Ylä-Mononen","satu.yla-mononen@pshp.fi",[48,65,78],{"facility":49,"status":50,"city":51,"state":52,"zip":26,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Central Finland Hospital Nova","NOT_YET_RECRUITING","Jyväskylä","Central Finland","Finland","FI",{"type":56,"coordinates":57},"Point",[58,59],25.72088,62.24147,{"lat":59,"lon":58},[62],{"name":63,"role":41,"phone":26,"phoneExt":26,"email":64},"Ville Ponkilainen, Assoc prof","ville.ponkilainen@ksshp.fi",{"facility":66,"status":67,"city":68,"state":69,"zip":70,"country":53,"countryCode":54,"cosmosGeoPoint":71,"geoPoint":75,"contacts":76},"Tampere Univeristy Hospital","RECRUITING","Tampere","Pirkanmaa","33520",{"type":56,"coordinates":72},[73,74],23.78712,61.49911,{"lat":74,"lon":73},[77],{"name":37,"role":41,"phone":26,"phoneExt":26,"email":43},{"facility":79,"status":50,"city":80,"state":81,"zip":26,"country":53,"countryCode":54,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"Turku University Hospital","Turku","Southwest Finland",{"type":56,"coordinates":83},[84,85],22.26869,60.45148,{"lat":85,"lon":84},[88],{"name":89,"role":41,"phone":26,"phoneExt":26,"email":90},"Elina Ekman, MD, PhD","elina.ekman@tyks.fi",{"type":38,"investigatorFullName":92,"investigatorTitle":93,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Aleksi Reito","Associate professor","100450932","limb-injuries-and-post-injury-rehabilitation-trials---tibial-shaft-fracture-100450932",false,"NCT05151926","Limb Injuries and Post Injury Rehabilitation Trials - Tibial Shaft Fracture","Limb Injuries and Post Injury Rehabilitation Trials - Tibial Shaft Fracture (LIMPER-TSF): a Protocol for Prospective, Randomized,Multicentre Trial Comparing the Early Partial and Early Full Weightbearing After Nailed Tibial Shaft Fracture","LIMPER-TSF","Inclusion Criteria:\n\n* AO\u002FOTA 42-A\u002FB acute, noncomminuted diaphyseal fracture of the tibia treated with intramedullary nailing with or without posterior malleolus screw fixation\n* operated within 72 hours of admittance\n* age between 18-65 years\n\nExclusion Criteria:\n\n* the inability to fill out the Finnish versions of the questionnaires\n* previous arthroplasty of the knee or the ankle of the fractured limb\n* previous ipsilateral below-knee fracture requiring surgical treatment or ankle arthrodesis\n* inability to co-operate\n* not living independently (institutionalized living before fracture)\n* open fracture (Gustilo grade 2 or over)\n* pathologic or stress fracture\n* multiple fractures requiring operative treatment in polytrauma patient\n* severe medical comorbidity impairing daily activities (inability to go climb three floors without assistance and stopping)\n* Body Mass Index over 40\n* unacceptably high risk of surgery due to severe medical comorbidities\n* severe substance abuse\n* patient is retired\n* age is less than 18 or more than 65\n* patient required a fasciotomy due to acute compartment syndrome during or after index surgery\n* inability to walk before fracture or a daily need of walking aid, such as crutches","ALL","18 Years","65 Years",{"count":106,"type":107},240,"ESTIMATED","INTERVENTIONAL",[110],"NA","Aim of our study is to compare immediate full weight-bearing and partial weight-bearing for 6 weeks after a tibial shaft fracture treated with intramedullary nailing. Co-primary outcome is return to work and physical component scale in the SF-36 questionnaire.",[113],"Tibia Fracture",[115,116],"intramedullary nail","weight-bearing","2024-12-31",{"date":119,"type":120},"2025-01-01","ACTUAL",{"date":122,"type":120},"2021-12-03",{"date":124,"type":107},"2027-12-31",{"name":5,"class":6},3]