[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589956":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":37,"responsibleParty":54,"collaborators":25,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":81,"overallStatus":40,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Shandong University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Linked-color imaging endoscopy","EXPERIMENTAL","Patients in this group will be carefully observed with LCI endoscopy during the colonoscopy withdraw.",[13],"Procedure: Linked-color imaging endoscopy",{"label":15,"type":16,"description":17,"interventionNames":18},"Chromoendoscopy with indigo carmine solution spray","ACTIVE_COMPARATOR","Patients in this group will be carefully observed with spraying indigo carmine solution during the colonoscopy withdraw.",[19],"Procedure: Chromoendoscopy with indigo carmine solution spray",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Patients will undergo chromoendoscopy with spraying indigo carmine.",[15],null,{"type":22,"name":9,"description":27,"armGroupLabels":28,"otherNames":25},"Patients will undergo Linked-color imaging endoscopy.",[9],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Rui Ji MD PHD","CONTACT","+86-18560086103","qljirui@email.sdu.edu.cn",{"name":36,"role":32,"phone":25,"phoneExt":25,"email":34},"Rui Ji MD PHD, +86-18560086103",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Qilu Hospital of Shandong University","RECRUITING","Jinan","Shandong","250012","China","CN",{"type":47,"coordinates":48},"Point",[49,50],116.99722,36.66833,{"lat":50,"lon":49},[53],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Yanqing Li","Director","100589956","linked-color-imaging-versus-indigo-carmine-pump-spraying-on-the-colorectal-adenoma-detection-rate-100589956",false,"NCT06961149","Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate","Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate: a Prospective , Randomized Controlled, Non-inferiority Study","Inclusion Criteria:\n\n1. Age between 45 and 85 years\n2. Patients with a history of colorectal adenoma\n3. Patients whose first-degree relatives have a history of colorectal cancer or colorectal adenoma\n4. Patients with gastrointestinal symptoms (abdominal pain, bloody stool, chronic diarrhea or constipation, Unexplained anemia or weight loss;\n5. Patients with positive Fecal Immunochemical Test\n\nExclusion Criteria:\n\n1. Patients with pregnancy, inflammatory bowel disease, familial adenomatosis polyposis, suspected CRC; intestinal obstruction, coagulopathy\n2. Patients with aspirin, clopidogrel or other anticoagulants\u002F antiplatelet drugs intake within 7 days\n3. Patents previous colorectal resection\n4. Patients with failed cecal intubation\n5. Patients with inadequate bowel preparation quality (BBPS≤5)\n6. Patients who refuse to participate or to provide informed consent","ALL","45 Years","85 Years",{"count":69,"type":70},352,"ESTIMATED","INTERVENTIONAL",[73],"NA","Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate, but considering the long withdrawal time of the endoscope and the resulting increase in time and cost. Linked-color imaging (LCI) is a newly developed image-enhanced endoscopy technology. It relies on wave length optimization of three colors (red, green, and blue) to make the lesions appear fuller. LCI improves the visibility of colorectal adenomas and polyps and may increase the detection rate of lesions. In order to explore the clinical application value of Linked-color imaging endoscopy, we performed a prospective, randomized controlled trial to compare adenoma detection rate of Linked-color imaging endoscopy and indigo carmine chromoendoscopy.",[76,77,78,79,80],"Colonic Polyps","Adenomatous Polyps","Adenoma Detection Rate","Chromoendoscopy","Colorectal Neoplasms",[78,82,79,83,84],"Linked-color imaging","Colonoscopy","Indigo Carmine","2025-05-05",{"date":87,"type":88},"2025-05-07","ACTUAL",{"date":90,"type":88},"2025-04-08",{"date":92,"type":70},"2026-04-01",{"name":5,"class":6},1]