[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582055":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":10,"centralContacts":67,"locations":74,"responsibleParty":228,"collaborators":10,"id":230,"slug":231,"hasResults":232,"nctId":233,"briefTitle":234,"officialTitle":234,"acronym":235,"eligibilityCriteria":236,"healthyVolunteers":232,"sex":237,"minAge":238,"maxAge":239,"enrollmentInfo":240,"targetDuration":10,"studyType":243,"phases":10,"briefSummary":244,"conditions":245,"keywords":247,"overallStatus":77,"whyStopped":10,"lastUpdateSubmitDate":252,"lastUpdatePostDateStruct":253,"startDateStruct":256,"completionDateStruct":258,"leadSponsor":260,"locationsCount":261},{"fullName":5,"class":6},"Novartis","INDUSTRY",[8,24],{"label":9,"type":10,"description":11,"interventionNames":12},"ASCVD patients",null,"Patients aged 18 and above with a history of ASCVD including peripheral arterial revascularization",[13,14,15,16,17,18,19,20,21,22,23],"Drug: Atorvastatin","Drug: Simvastatin","Drug: Rozuvastatin","Drug: Ezetimibe","Drug: Niacin","Drug: Ciprofibrate","Drug: Fenofibrate","Drug: Bezafibrate","Drug: Evolocumab","Drug: Alirocumab","Drug: Inclisiran",{"label":25,"type":10,"description":26,"interventionNames":27},"Relatives of the ASCVD patients","A first-degree relative of the ASCVD patient (patient's parents and children) with Lp(a) ≥125 nmol\u002FL.",[13,14,15,16,17,18,19,20,21,22,23],[29,34,37,40,43,46,50,53,56,60,63],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":10},"DRUG","Atorvastatin","3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors (statins)",[9,25],{"type":30,"name":35,"description":32,"armGroupLabels":36,"otherNames":10},"Simvastatin",[9,25],{"type":30,"name":38,"description":32,"armGroupLabels":39,"otherNames":10},"Rozuvastatin",[9,25],{"type":30,"name":41,"description":41,"armGroupLabels":42,"otherNames":10},"Ezetimibe",[9,25],{"type":30,"name":44,"description":44,"armGroupLabels":45,"otherNames":10},"Niacin",[9,25],{"type":30,"name":47,"description":48,"armGroupLabels":49,"otherNames":10},"Ciprofibrate","Fibrates",[9,25],{"type":30,"name":51,"description":48,"armGroupLabels":52,"otherNames":10},"Fenofibrate",[9,25],{"type":30,"name":54,"description":48,"armGroupLabels":55,"otherNames":10},"Bezafibrate",[9,25],{"type":30,"name":57,"description":58,"armGroupLabels":59,"otherNames":10},"Evolocumab","PCSK9 inhibitor",[9,25],{"type":30,"name":61,"description":58,"armGroupLabels":62,"otherNames":10},"Alirocumab",[9,25],{"type":30,"name":64,"description":65,"armGroupLabels":66,"otherNames":10},"Inclisiran","Small interfering RNA",[9,25],[68,73],{"name":69,"role":70,"phone":71,"phoneExt":10,"email":72},"Novartis Pharmaceuticals","CONTACT","+41613241111","novartis.email@novartis.com",{"name":69,"role":70,"phone":10,"phoneExt":10,"email":10},[75,88,93,101,109,117,125,130,135,143,151,159,167,175,183,191,199,207,215,223],{"facility":76,"status":77,"city":78,"state":10,"zip":79,"country":80,"countryCode":81,"cosmosGeoPoint":82,"geoPoint":87,"contacts":10},"Novartis Investigative Site","RECRUITING","Chelyabinsk","454048","Russia","RU",{"type":83,"coordinates":84},"Point",[85,86],61.42877,55.1611,{"lat":86,"lon":85},{"facility":76,"status":77,"city":78,"state":10,"zip":89,"country":80,"countryCode":81,"cosmosGeoPoint":90,"geoPoint":92,"contacts":10},"454076",{"type":83,"coordinates":91},[85,86],{"lat":86,"lon":85},{"facility":76,"status":77,"city":94,"state":10,"zip":95,"country":80,"countryCode":81,"cosmosGeoPoint":96,"geoPoint":100,"contacts":10},"Kaluga","248000",{"type":83,"coordinates":97},[98,99],36.27,54.53063,{"lat":99,"lon":98},{"facility":76,"status":77,"city":102,"state":10,"zip":103,"country":80,"countryCode":81,"cosmosGeoPoint":104,"geoPoint":108,"contacts":10},"Kemerovo","650002",{"type":83,"coordinates":105},[106,107],86.10435,55.35417,{"lat":107,"lon":106},{"facility":76,"status":77,"city":110,"state":10,"zip":111,"country":80,"countryCode":81,"cosmosGeoPoint":112,"geoPoint":116,"contacts":10},"Krasnoyarsk","680022",{"type":83,"coordinates":113},[114,115],92.93136,56.03742,{"lat":115,"lon":114},{"facility":76,"status":77,"city":118,"state":10,"zip":119,"country":80,"countryCode":81,"cosmosGeoPoint":120,"geoPoint":124,"contacts":10},"Moscow","119881",{"type":83,"coordinates":121},[122,123],37.61781,55.75204,{"lat":123,"lon":122},{"facility":76,"status":77,"city":118,"state":10,"zip":126,"country":80,"countryCode":81,"cosmosGeoPoint":127,"geoPoint":129,"contacts":10},"121552",{"type":83,"coordinates":128},[122,123],{"lat":123,"lon":122},{"facility":76,"status":77,"city":118,"state":10,"zip":131,"country":80,"countryCode":81,"cosmosGeoPoint":132,"geoPoint":134,"contacts":10},"125284",{"type":83,"coordinates":133},[122,123],{"lat":123,"lon":122},{"facility":76,"status":77,"city":136,"state":10,"zip":137,"country":80,"countryCode":81,"cosmosGeoPoint":138,"geoPoint":142,"contacts":10},"Omsk","644024",{"type":83,"coordinates":139},[140,141],73.36859,54.99244,{"lat":141,"lon":140},{"facility":76,"status":77,"city":144,"state":10,"zip":145,"country":80,"countryCode":81,"cosmosGeoPoint":146,"geoPoint":150,"contacts":10},"Perm","614002",{"type":83,"coordinates":147},[148,149],56.25017,58.01046,{"lat":149,"lon":148},{"facility":76,"status":77,"city":152,"state":10,"zip":153,"country":80,"countryCode":81,"cosmosGeoPoint":154,"geoPoint":158,"contacts":10},"Ryazan","390039",{"type":83,"coordinates":155},[156,157],39.70415,54.62696,{"lat":157,"lon":156},{"facility":76,"status":77,"city":160,"state":10,"zip":161,"country":80,"countryCode":81,"cosmosGeoPoint":162,"geoPoint":166,"contacts":10},"Surgut","628403",{"type":83,"coordinates":163},[164,165],73.41775,61.25757,{"lat":165,"lon":164},{"facility":76,"status":77,"city":168,"state":10,"zip":169,"country":80,"countryCode":81,"cosmosGeoPoint":170,"geoPoint":174,"contacts":10},"Tomsk","634009",{"type":83,"coordinates":171},[172,173],84.98216,56.50049,{"lat":173,"lon":172},{"facility":76,"status":77,"city":176,"state":10,"zip":177,"country":80,"countryCode":81,"cosmosGeoPoint":178,"geoPoint":182,"contacts":10},"Tyumen","625026",{"type":83,"coordinates":179},[180,181],65.52722,57.15222,{"lat":181,"lon":180},{"facility":76,"status":77,"city":184,"state":10,"zip":185,"country":80,"countryCode":81,"cosmosGeoPoint":186,"geoPoint":190,"contacts":10},"Vladimir","600020",{"type":83,"coordinates":187},[188,189],40.39976,56.13854,{"lat":189,"lon":188},{"facility":76,"status":77,"city":192,"state":10,"zip":193,"country":80,"countryCode":81,"cosmosGeoPoint":194,"geoPoint":198,"contacts":10},"Vladivostok","690000",{"type":83,"coordinates":195},[196,197],131.87353,43.10562,{"lat":197,"lon":196},{"facility":76,"status":77,"city":200,"state":10,"zip":201,"country":80,"countryCode":81,"cosmosGeoPoint":202,"geoPoint":206,"contacts":10},"Voronezh","394018",{"type":83,"coordinates":203},[204,205],39.19204,51.66833,{"lat":205,"lon":204},{"facility":76,"status":77,"city":208,"state":10,"zip":209,"country":80,"countryCode":81,"cosmosGeoPoint":210,"geoPoint":214,"contacts":10},"Yakutsk","677013",{"type":83,"coordinates":211},[212,213],129.72288,62.03114,{"lat":213,"lon":212},{"facility":76,"status":77,"city":216,"state":10,"zip":217,"country":80,"countryCode":81,"cosmosGeoPoint":218,"geoPoint":222,"contacts":10},"Yekaterinburg","620137",{"type":83,"coordinates":219},[220,221],60.61529,56.85733,{"lat":221,"lon":220},{"facility":76,"status":77,"city":216,"state":10,"zip":224,"country":80,"countryCode":81,"cosmosGeoPoint":225,"geoPoint":227,"contacts":10},"620144",{"type":83,"coordinates":226},[220,221],{"lat":221,"lon":220},{"type":229,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100582055","lipoproteina-levels-in-patients-with-atherosclerotic-cardiovascular-diseases-in-russia-100582055",false,"NCT06858332","Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia","STaRT","Inclusion Criteria:\n\n1. Written informed consent (signed and dated).\n2. Males and females aged ≥18 years.\n3. Presence of one of the following ASCVDs for at least 3 months within the 2 years prior to signing the informed consent to participate in this study:\n\n   * history of MI;\n   * history of IS and\u002For TIA;\n   * IHD confirmed by coronary angiography (stenosis ≥50%);\n   * any revascularization surgery (emergency or planned), including CABG, PCI, carotid endarterectomy or carotid\u002Fintracranial stenting;\n   * peripheral artery disease (intermittent claudication with ankle-brachial index ≤0.90 and\u002For lower limb amputation or revascularization in case of lower limb ischemia).\n\nExclusion Criteria:\n\n1. Acute infectious and inflammatory diseases, such as COVID-19, in the month leading up to the Screening visit.\n2. Lp(a)-lowering therapy\u002Fmethods (Lp(a) apheresis with PCSK9 inhibitors, inclisiran prior to the Screening visit) in the medical history before the Screening visit.\n3. Participation in any interventional clinical study with investigational or marketed medicinal products at the time of enrollment.\n4. Participation in other real-world clinical studies.\n5. Stages 4 and 5 of chronic kidney disease (glomerular filtration rate CKD-EPI \\\u003C30 mL\u002Fmin\u002F1.73 m2) and\u002For hepatic disease (total bilirubin: 2 × ULN).\n\nOther protocol-defined inclusion\u002Fexclusion criteria may apply.","ALL","18 Years","99 Years",{"count":241,"type":242},2382,"ESTIMATED","OBSERVATIONAL","This study has the purpose to answer how the Lipoprotein(a) (Lp(a)) level is distributed among Atherosclerotic cardiovascular disease (ASCVD) patients in Russia, and what is the connection between elevated levels of this parameter and the cardiovascular disease (CVD) risk.",[246],"Atherosclerotic Cardiovascular Disease",[248,249,250,251],"lipoprotein(a),","ASCVD,","cardiovascular disease,","CVD","2025-08-01",{"date":254,"type":255},"2025-08-03","ACTUAL",{"date":257,"type":255},"2025-04-15",{"date":259,"type":242},"2027-09-30",{"name":69,"class":6},20]