[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100307294":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":17,"locations":22,"responsibleParty":39,"collaborators":7,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":7,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":7,"enrollmentInfo":51,"targetDuration":7,"studyType":54,"phases":7,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":25,"whyStopped":7,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Oncology Institute of Southern Switzerland","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Liquid Biopsy","Assessing whether plasma cell free DNA improves the accuracy of early prediction of cure in mature B-cell tumor patients and whether it represents an accessible source of tumor DNA for the sensitive identification of genetic biomarkers that, at disease presentation, refine the diagnostic workup in mature B-cell tumor patients and, upon treatment, early identify the emergence of resistance mutations.",[14],{"name":15,"affiliation":5,"role":16},"Davide Rossi, MD, PhD","PRINCIPAL_INVESTIGATOR",[18],{"name":15,"role":19,"phone":20,"phoneExt":7,"email":21},"CONTACT","+41 091 811 8540","davide.rossi@eoc.ch",[23],{"facility":24,"status":25,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Institute of Oncology Research","RECRUITING","Bellinzona","Canton Ticino","6500","Switzerland","CH",{"type":32,"coordinates":33},"Point",[34,35],9.01703,46.19278,{"lat":35,"lon":34},[38],{"name":15,"role":19,"phone":7,"phoneExt":7,"email":21},{"type":16,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Davide Rossi","MD, PhD","100307294","liquid-biopsy-in-mature-b-cell-tumors-100307294",false,"NCT03280394","Liquid Biopsy in Mature B-cell Tumors","Prospective, Observational, Multi-centred, Non-interventional Research Project on Plasma Cell Free DNA Genotyping as a Tool to Inform Mature B-cell Tumor Management","Inclusion Criteria:\n\n* Male or female adults 18 years or older\n* Documented diagnosis of mature B-cell tumor according to WHO 2008 criteria\n* Willing and able to comply with scheduled study procedures\n* Evidence of a signed informed consent","ALL","18 Years",{"count":52,"type":53},444,"ESTIMATED","OBSERVATIONAL","The study aims at assessing whether cell free DNA genotyping can improve the accuracy of early prediction of cure in mature B-cell tumor patients and whether it represents an accessible source of tumor DNA for the sensitive identification of genetic biomarkers that refine the diagnostic workup, stratify prognosis and identify the emergence of drug-resistance mutations during treatment.",[57],"Mature B-Cell Neoplasm",[59,60,61,62,63,64],"Liquid biopsy","Classical Hodgkin Lymphoma","Diffuse Large B Cell Lymphoma","Follicular Lymphoma","Mantle Cell Lymphoma","Mutations","2023-10-31",{"date":67,"type":68},"2023-11-01","ACTUAL",{"date":70,"type":68},"2017-09-01",{"date":72,"type":53},"2027-12-31",{"name":5,"class":6},1]