[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100510193":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":41,"responsibleParty":400,"collaborators":26,"id":403,"slug":404,"hasResults":405,"nctId":406,"briefTitle":407,"officialTitle":408,"acronym":26,"eligibilityCriteria":409,"healthyVolunteers":405,"sex":410,"minAge":411,"maxAge":412,"enrollmentInfo":413,"targetDuration":26,"studyType":416,"phases":417,"briefSummary":419,"conditions":420,"keywords":423,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":428,"lastUpdatePostDateStruct":429,"startDateStruct":432,"completionDateStruct":434,"leadSponsor":436,"locationsCount":437},{"fullName":5,"class":6},"Zhejiang University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"LISH （Laparoscopic Ileocecal-Sparing Right Hemicolectomy）group","EXPERIMENTAL","In LISH group, patients suffering from cancer of the hepatic flexure and proximal transverse colon will be undergoing a novel radical right hemicolectomy technique that allows for the preservation of the ileocecal region.",[13],"Procedure: LISH （Laparoscopic Ileocecal-Sparing Right Hemicolectomy）",{"label":15,"type":16,"description":17,"interventionNames":18},"TRH （Traditional Right Hemicolectomy）group","ACTIVE_COMPARATOR","In TRH group, patients suffering from cancer of the hepatic flexure and proximal transverse colon will be undergoing the traditional radical right hemicolectomy.",[19],"Procedure: TRH（Traditional Laparoscopic Right Hemicolectomy）",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","LISH （Laparoscopic Ileocecal-Sparing Right Hemicolectomy）","Preserve the ileocolic blood vessels, and perform dissection of lymph node groups 203, 202, and 201d along the root of ICV(Ileocolic artery)\u002FICA(Ileocolic vein). Group 201d lymph nodes are defined as the distal lymph nodes of the ileocolic vessels (colonic branch). Use an intracavitary cutting and sealing device to transect the proximal colon along the predetermined margin, and transect the transverse colon at 10cm distal to the tumor. Perform ileocecal-transverse colonic anastomosis.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"TRH（Traditional Laparoscopic Right Hemicolectomy）","Transect the root of the ileocolic vessels and perform dissection of lymph node groups 203, 202, and 201; sever the roots of the right colic and middle colic vessels, and clear the surrounding lymphoadipose tissue (lymph node groups 211\u002F212\u002F213 and 221\u002F222\u002F223). Transect the transverse colon 10cm distal to the tumor and cut the terminal ileum 10cm from the ileocecal junction. Perform ileum-to-transverse colon anastomosis.",[15],[32],{"name":33,"affiliation":34,"role":35},"Kefeng Ding, PhD","Second Affiliated Hospital, School of Medicine, Zhejiang University","PRINCIPAL_INVESTIGATOR",[37],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","86-571-87784720","dingkefeng@zju.edu.cn",[42,59,76,85,98,111,126,136,145,158,167,180,195,208,217,230,243,255,270,282,291,301,314,326,339,358,367,376,388],{"facility":43,"status":44,"city":45,"state":46,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"the First Affiliated Hospital of Bengbu Medical Collage","RECRUITING","Bengbu","Anhui","China","CN",{"type":50,"coordinates":51},"Point",[52,53],117.36083,32.94083,{"lat":53,"lon":52},[56,58],{"name":57,"role":38,"phone":26,"phoneExt":26,"email":26},"Muling Liu, 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M.D.",{"facility":137,"status":138,"city":139,"state":114,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":140,"geoPoint":144,"contacts":26},"The First Affiliated Hospital of Xiamen University","NOT_YET_RECRUITING","Xiamen",{"type":50,"coordinates":141},[142,143],118.08187,24.47979,{"lat":143,"lon":142},{"facility":146,"status":44,"city":147,"state":148,"zip":149,"country":47,"countryCode":48,"cosmosGeoPoint":150,"geoPoint":154,"contacts":155},"Guangdong Second Provincial General Hospital","Guangzhou","Guangdong","510317",{"type":50,"coordinates":151},[152,153],113.25,23.11667,{"lat":153,"lon":152},[156],{"name":157,"role":38,"phone":26,"phoneExt":26,"email":26},"Han Fanghai, Prof.",{"facility":159,"status":44,"city":147,"state":148,"zip":160,"country":47,"countryCode":48,"cosmosGeoPoint":161,"geoPoint":163,"contacts":164},"The Sixth Affiliated Hospital of Sun Yat-sen 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Prof.",{"facility":244,"status":44,"city":245,"state":233,"zip":246,"country":47,"countryCode":48,"cosmosGeoPoint":247,"geoPoint":251,"contacts":252},"The Affiliated Hospital of Qingdao University","Qingdao","266003",{"type":50,"coordinates":248},[249,250],120.38042,36.06488,{"lat":250,"lon":249},[253],{"name":254,"role":38,"phone":26,"phoneExt":26,"email":26},"Zhou Yanbin, Prof.",{"facility":256,"status":44,"city":257,"state":258,"zip":259,"country":47,"countryCode":48,"cosmosGeoPoint":260,"geoPoint":264,"contacts":265},"Changhai Hospital of Shanghai","Shanghai","Shanghai Municipality","200433",{"type":50,"coordinates":261},[262,263],121.45806,31.22222,{"lat":263,"lon":262},[266,268],{"name":267,"role":38,"phone":26,"phoneExt":26,"email":26},"Wei Zhang",{"name":269,"role":35,"phone":26,"phoneExt":26,"email":26},"Wei Zhang, MD",{"facility":271,"status":44,"city":257,"state":258,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":272,"geoPoint":274,"contacts":275},"Fudan University Shanghai Cancer Center",{"type":50,"coordinates":273},[262,263],{"lat":263,"lon":262},[276,278,280,281],{"name":277,"role":38,"phone":26,"phoneExt":26,"email":26},"Ye Xu, phD",{"name":279,"role":38,"phone":26,"phoneExt":26,"email":26},"Xinxiang Li, phD",{"name":277,"role":35,"phone":26,"phoneExt":26,"email":26},{"name":279,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":283,"status":44,"city":257,"state":258,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":284,"geoPoint":286,"contacts":287},"Ruijin Hospital Affiliated of The Shanghai Jiao Tong University Medical School",{"type":50,"coordinates":285},[262,263],{"lat":263,"lon":262},[288,290],{"name":289,"role":38,"phone":26,"phoneExt":26,"email":26},"Bo Feng, phD",{"name":289,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":292,"status":44,"city":293,"state":294,"zip":295,"country":47,"countryCode":48,"cosmosGeoPoint":296,"geoPoint":300,"contacts":26},"The first affiliated hospital of xi'an jiaotong university","Xi’an","Shanxi","710000",{"type":50,"coordinates":297},[298,299],113.52486,35.99785,{"lat":299,"lon":298},{"facility":302,"status":44,"city":303,"state":304,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":305,"geoPoint":309,"contacts":310},"West China Hospital of Sichuang University","Chengdu","Sichuan",{"type":50,"coordinates":306},[307,308],104.06667,30.66667,{"lat":308,"lon":307},[311,313],{"name":312,"role":38,"phone":26,"phoneExt":26,"email":26},"Ziqiang Wang, phD",{"name":312,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":315,"status":44,"city":316,"state":316,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":317,"geoPoint":321,"contacts":322},"The Cancer Hospital Affiliated of The Xingjiang University Medical School","Xinjiang",{"type":50,"coordinates":318},[319,320],110.38311,40.91904,{"lat":320,"lon":319},[323,325],{"name":324,"role":38,"phone":26,"phoneExt":26,"email":26},"Haijiang Wang, phD",{"name":324,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":327,"status":44,"city":328,"state":329,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":330,"geoPoint":334,"contacts":335},"Yunnan Cancer Hospital","Kunming","Yunnan",{"type":50,"coordinates":331},[332,333],102.71833,25.03889,{"lat":333,"lon":332},[336,338],{"name":337,"role":38,"phone":26,"phoneExt":26,"email":26},"Yunfeng Li, phD",{"name":337,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":340,"status":44,"city":341,"state":342,"zip":343,"country":47,"countryCode":48,"cosmosGeoPoint":344,"geoPoint":348,"contacts":349},"Second Affiliated Hospital Zhejiang University College of Medicine","Hangzhou","Zhejiang","310999",{"type":50,"coordinates":345},[346,347],120.16142,30.29365,{"lat":347,"lon":346},[350,353,357],{"name":351,"role":38,"phone":352,"phoneExt":26,"email":40},"Ke-Feng Ding, phD\u002FMD","86-571-87784827",{"name":354,"role":38,"phone":355,"phoneExt":26,"email":356},"Jian Wang, phD\u002FMD","0571-87784720","wangjian519@zju.edu.cn",{"name":351,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":359,"status":44,"city":341,"state":342,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":360,"geoPoint":362,"contacts":363},"Sir Run Run Shaw Hospital, Zhejiang University School of medicien",{"type":50,"coordinates":361},[346,347],{"lat":347,"lon":346},[364,366],{"name":365,"role":38,"phone":26,"phoneExt":26,"email":26},"Xuefeng Huang, phD",{"name":365,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":368,"status":138,"city":341,"state":342,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":369,"geoPoint":371,"contacts":372},"Zhejiang Cancer Hospital",{"type":50,"coordinates":370},[346,347],{"lat":347,"lon":346},[373,375],{"name":374,"role":38,"phone":26,"phoneExt":26,"email":26},"Haixing Ju, phD",{"name":374,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":377,"status":44,"city":378,"state":342,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":379,"geoPoint":383,"contacts":384},"Jinhua Municipal Central Hospital","Jinhua",{"type":50,"coordinates":380},[381,382],119.64421,29.10678,{"lat":382,"lon":381},[385,387],{"name":386,"role":38,"phone":26,"phoneExt":26,"email":26},"Jinlin Du, phD",{"name":386,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":389,"status":44,"city":390,"state":342,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":391,"geoPoint":395,"contacts":396},"Ningbo No.2 Hospital","Ningbo",{"type":50,"coordinates":392},[393,394],121.54945,29.87819,{"lat":394,"lon":393},[397,399],{"name":398,"role":38,"phone":26,"phoneExt":26,"email":26},"Xiaoyu Dai, phD",{"name":398,"role":35,"phone":26,"phoneExt":26,"email":26},{"type":35,"investigatorFullName":401,"investigatorTitle":402,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Ding Ke-Feng","Professor","100510193","lish-trial-for-the-hepatic-flexure-and-proximal-transverse-colon-cancer-100510193",false,"NCT05923255","LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer","Laparoscopic Ileocecal-Sparing Right Hemicolectomy for Cancer of the Hepatic Flexure and Proximal Transverse Colon -- A Prospective, Multicenter Randomized Control Clinical Trial","Inclusion Criteria:\n\n1. Age between 18-75 years old\n2. ASA classification ≤III\n3. Colon adenocarcinoma confirmed by endoscopy and pathological biopsy\n4. Enhanced abdominal CT indicating the primary lesion is located in the hepatic flexure of the colon or proximal transverse colon (proximal 1\u002F3 of the transverse colon)\n5. Preoperative clinical staging: TanyNanyM0\n6. Patients able to understand the study protocol, willing to participate in the research, and providing written informed consent\n\nExclusion Criteria:\n\n1. Preoperative examination indicates synchronous multiple primary colorectal cancers or other diseases requiring bowel segment resection\n2. Preoperative imaging or intraoperative exploration reveals: 1) tumor involving surrounding organs requiring combined organ resection; 2) presence of distant metastasis; 3) inability to perform R0 resection; 4) fused and fixed lymph nodes at the root of the ileocolic vessels\n3. Additional radical surgery following Endoscopic Mucosal Resection (EMR) and Endoscopic Submucosal Dissection (ESD) procedures\n4. History of any other malignant tumor within the last 5 years or familial adenomatous polyposis, except for cured in situ cervical cancer, basal cell carcinoma, papillary thyroid carcinoma, or skin squamous cell carcinoma\n5. Presence of bowel obstruction, bowel perforation, or intestinal bleeding requiring emergency surgery\n6. Patients unsuitable for or unable to tolerate laparoscopic surgery\n7. Pregnant or lactating women\n8. Patients with a history of psychiatric disorders\n9. Patients who have received neoadjuvant therapy prior to surgery\n10. Patients deemed unsuitable for the study by MDT discussion\n11. Patients unable to understand the study's conditions and objectives, and refusing to sign informed consent.","ALL","18 Years","75 Years",{"count":414,"type":415},568,"ESTIMATED","INTERVENTIONAL",[418],"NA","The goal of this clinical trial is to compare the long-term outcomes of Laparoscopic Ileocecal-Sparing Right Hemicolectomy(LISH) compared to traditional laparoscopic right hemicolectomy(TRH) in the treatment of hepatic flexure colon cancer and proximal transverse colon cancer.",[421,422],"Hepatic Flexure Colon Cancer","Proximal Transverse Colon Cancer",[424,425,426,427],"hepatic flexure colon cancer","proximal transverse colon cancer","ileocecus-sparing","laparoscopic right hemicolectomy","2026-01-25",{"date":430,"type":431},"2026-01-27","ACTUAL",{"date":433,"type":431},"2023-05-14",{"date":435,"type":415},"2031-05-14",{"name":5,"class":6},29]