[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100316592":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":25,"responsibleParty":43,"collaborators":18,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":18,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":18,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":67,"whyStopped":18,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Yonsei University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ablation","ACTIVE_COMPARATOR","Patients in this group are treated with radio-frequency catheter ablation.",[13],"Drug: midazolam with fentanyl",{"label":15,"type":16,"description":17,"interventionNames":18},"non-ablation","NO_INTERVENTION","Patients in this group are treated with rate control medications (e.g., beta blocker, calcium channel blocker, and digitalis) and anti-arrhythmic drugs. They also can be treated with DC cardio-version.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DRUG","midazolam with fentanyl","Radio-frequency catheter ablation is performed in the post-absorptive state after sedation with midazolam and fentanyl. Multipolar catheters were positioned in the coronary sinus, His, and the right atrium. The three-dimensional LA geometry was reconstructed using a CARTO or NavX electroanatomical mapping system. Circumferential pulmonary vein isolation was performed in all patients using a irrigated-tip catheter. A circular mapping catheter was used to confirm the isolation of the pulmonary veins. Successful ablation was defined by the elimination of all the pulmonary vein potentials along the antrum or inside the veins. If the AF was not terminated after elimination of all the pulmonary vein potentials, linear ablation and complex fragmented atrial electrogram ablation were performed.",[9],[26],{"facility":27,"status":18,"city":28,"state":18,"zip":29,"country":30,"countryCode":18,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Division of Cardiology, Yonsei University Health System, Yonsei University College of Medicine","Seoul","03722","South Korea",{"type":32,"coordinates":33},"Point",[34,35],126.9784,37.566,{"lat":35,"lon":34},[38],{"name":39,"role":40,"phone":41,"phoneExt":18,"email":42},"Boyoung Joung, MD, Ph.D","CONTACT","82-2-2228-8460","cby6908@yuhs.ac",{"type":44,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100316592","long-term-evaluation-and-management-of-atrial-fibrillation-in-pacemaker-patients-100316592",false,"NCT03401593","Long Term Evaluation and Management of Atrial Fibrillation in Pacemaker Patients","Long Term Evaluation and Management of Atrial Fibrillation in Pacemaker Patients (AF-pacemaker Tx Study)","Inclusion Criteria:\n\n* Patients who developed atrial fibrillation\u002Fflutter\u002Ftachycardia after pacemaker implantation among AF-pacemaker study (ClinicalTrials.gov Identifier: NCT03303872).\n* Age: 18-80 years\n* Patients eligible for the indications for permanent pacemaker implantation in accordance with 2016 revised Korean indication guideline on cardiac pacemaker implantation\n* Estimated percentage of atrial pacing \\>40% under sinus rhythm (LR≥60bpm, close hysteresis and rest rate)\n* Estimated percentage of ventricular pacing \\>40% under sinus rhythm (LR≥40bpm, DDD pacing, close hysteresis and rest rate)\n* Patients who are willing to sign the informed consent.\n* Patients who are willing to receive the implantation and post-operative follow-up.\n\nExclusion Criteria:\n\n* Persistent or permanent AF\n* Severe hepatic and renal insufficiency (AST or ALT ≥ three times of normal upper limit; SCr \\> 3.5 mg\u002Fdl or Ccr \\\u003C 30ml\u002Fmin)\n* Thyroid gland dysfunction\n* Pregnancy\n* Malignant tumor\n* Severe organic heart disease (such as moderate to severe mitral regurgitation, severe valvular regurgitation and stenosis, dilated cardiomyopathy, hypertrophic cardiomyopathy, severe heart valve disease)\n* Life expectancy \\\u003C 12 months\n* Patients unable or unwilling to cooperate in the study procedures.","ALL","19 Years","80 Years",{"count":56,"type":57},135,"ESTIMATED","INTERVENTIONAL",[60],"NA","This study is prospective randomized study which was performed in multicenter (General Hospital) in Korea. Inclusion criteria is patients who developed atrial fibrillation\u002Fflutter\u002Ftachycardia after pacemaker implantation among AF-pacemaker study (ClinicalTrials.gov Identifier: NCT03303872). The purpose is to investigate the recurrence rate of AF\u002FAFL\u002FAT in both groups after randomization for 60 months (5 years) in patients post pacemaker implantation and assess long term clinical results.",[63],"Permanent Pacemaker Implantation",[9,65,66],"atrial fibrillation","stroke","NOT_YET_RECRUITING","2019-08-28",{"date":70,"type":71},"2019-08-29","ACTUAL",{"date":73,"type":57},"2019-10",{"date":75,"type":57},"2028-06",{"name":5,"class":6},1]