[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598956":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":11,"locations":17,"responsibleParty":41,"collaborators":43,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":7,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":7,"enrollmentInfo":55,"targetDuration":7,"studyType":58,"phases":7,"briefSummary":59,"conditions":60,"keywords":7,"overallStatus":33,"whyStopped":7,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Region Skane","OTHER",null,[9],{"type":6,"name":10,"description":10,"armGroupLabels":7,"otherNames":7},"No intervention is used.",[12],{"name":13,"role":14,"phone":15,"phoneExt":7,"email":16},"Marie Asp, MD, PhD","CONTACT","+46702731013","marie.asp@skane.se",[18,31],{"facility":19,"status":20,"city":21,"state":7,"zip":22,"country":23,"countryCode":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":7},"Psychiatry Reserach Unit","ACTIVE_NOT_RECRUITING","Lund","221 85","Sweden","SE",{"type":26,"coordinates":27},"Point",[28,29],13.19321,55.70584,{"lat":29,"lon":28},{"facility":32,"status":33,"city":21,"state":7,"zip":22,"country":23,"countryCode":24,"cosmosGeoPoint":34,"geoPoint":36,"contacts":37},"Research Unit, Office of Psychiatricy, habilitation and technical aid","RECRUITING",{"type":26,"coordinates":35},[28,29],{"lat":29,"lon":28},[38],{"name":39,"role":14,"phone":15,"phoneExt":7,"email":40},"Marie Asp, PhD","marie.asp@med.lu.se",{"type":42,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[44],{"name":45,"class":6},"Lund University","100598956","long-term-follow-up-of-depressive-disorders-in-psychiatric-care-100598956",false,"NCT07078227","Long-term Follow-up of Depressive Disorders in Psychiatric Care","5 Years Follow-up of the Study: \"Pharmacogenetics in Depressed Patients With Specific Focus on Difficult-to-treat Depresssion, Suicide Attempt and CYP2D6\"","Inclusion Criteria:\n\nParticipation in the study \"Pharmacogenetics in depressive patients with specific focus on difficult-to-treat depression, suicide attempt and CYP2D6\"\n\nExclusion Criteria:\n\nNot wanting to participate in the follow-up study","ALL","18 Years",{"count":56,"type":57},415,"ESTIMATED","OBSERVATIONAL","The project investigates long-term prognosis and predictors of treatment outcomes for difficult-to-treat depression in patients in secondary psychiatric care. The current patient cohort was collected in 2012-2021 in the study \"Pharmacogenetics in patients with depression with specific focus on difficult-to-treat depression, suicide attempt and CYP2D6\". The cohort consists of 415 patients, examined carefully regarding diagnostic assessment and earlier treatment. All participants were also genotyped for the drug metabolizing enzymes CYP2D6 and CYP2C19. Blood samples were stored in biobank for other analyses linked to prognostic markers.\n\nThe patient cohort will now be followed up with a review of medical records and extraction of register data for a period of 5 years after their participation in the original study. The purpose of the study is to improve treatment and increase knowledge about long-term prognosis in difficult-to-treat depression. This is done by examining symptom profiles, monitoring clinical course and suicidality, and examining prognostic markers.",[61,62,63,64,65,66],"Depression","Psychiatric Diagnosis","Personality Disorders","Suicide, Attempted","CYP2D6 Polymorphism","Anhedonia","2026-04-24",{"date":69,"type":70},"2026-04-30","ACTUAL",{"date":72,"type":70},"2025-06-01",{"date":74,"type":57},"2026-12-31",{"name":5,"class":6},2]