[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586274":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":38,"responsibleParty":54,"collaborators":26,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":26,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":26,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":26,"overallStatus":41,"whyStopped":26,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Al Hayah University In Cairo","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Multidisciplinary Physiotherapy Program","EXPERIMENTAL","Participants in this arm will undergo a standardized multidisciplinary physiotherapy program consisting of:\n\nSpecific Exercise Therapy: 30-60-minute sessions conducted thrice weekly for 8 weeks (supervised) with subsequent home-based maintenance.\n\nManual Therapy: 20-30-minute soft-tissue mobilization sessions twice weekly for 4 weeks.\n\nEducation: Three sessions (in-person and online) focusing on pain neuroscience and self-management strategies.\n\nMind-Body Interventions: 40-minute yoga or tai chi sessions once weekly for 6 weeks.",[13],"Behavioral: Multidisciplinary Physiotherapy Program (MD Physio)",{"label":15,"type":16,"description":17,"interventionNames":18},"Control - Standard Care","ACTIVE_COMPARATOR","Participants in the control arm will receive \"standard care\" as currently practiced. This includes routine follow-up and basic physiotherapy advice typically provided to breast cancer survivors without the structured, multidisciplinary program.",[19],"Behavioral: Standard Physiotherapy Care",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Multidisciplinary Physiotherapy Program (MD Physio)","A comprehensive program that integrates:\n\nSpecific Exercise Therapy: Supervised stretching and strengthening sessions (30-60 minutes\u002Fsession, 3× per week for 8 weeks) followed by a prescribed home-based maintenance regimen.\n\nManual Therapy: Targeted soft-tissue mobilization and myofascial release (20-30 minutes\u002Fsession, twice per week for 4 weeks).\n\nEducation Sessions: Three sessions (both in-person and online) covering pain neuroscience and self-management techniques.\n\nMind-Body Interventions: Weekly 40-minute sessions of yoga or tai chi for 6 weeks.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Standard Physiotherapy Care","Routine care involves standard follow-up with basic physiotherapy advice as currently provided to breast cancer survivors. This serves as the active comparator in the trial.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Mohamed ElMeligie, Ph.D","CONTACT","01159880001","+20","mohamed.elmeligie@ahuc.edu.eg",[39],{"facility":40,"status":41,"city":42,"state":26,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Faculty of Physical Therapy, Al Hayah University","RECRUITING","Cairo","12311","Egypt","EG",{"type":47,"coordinates":48},"Point",[49,50],31.24967,30.06263,{"lat":50,"lon":49},[53],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},{"type":55,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100586274","long-term-multidisciplinary-physiotherapy-for-breast-cancer-survivors-a-randomized-controlled-trial-100586274",false,"NCT06913244","Long-Term Multidisciplinary Physiotherapy for Breast Cancer Survivors: A Randomized Controlled Trial","Long-Term Multidisciplinary Physiotherapy for Breast Cancer Survivors: Evaluation of the 12-Month Effectiveness on Pain, Upper Limb Function, and Cancer-Related Fatigue in a Multi-Center, Parallel-Group Randomized Controlled Trial","Inclusion Criteria:\n\nWomen aged between 18 and 65 years. History of breast cancer surgery (with or without axillary lymph node dissection).\n\nCompleted acute cancer treatment (surgery, chemotherapy, and\u002For radiation) at least 6 months prior to enrollment.\n\nCurrently in the survivorship phase, with no active evidence of disease.\n\nExperiencing persistent sequelae related to treatment, such as:\n\nModerate to severe pain (e.g., VAS score ≥ 30 on a 0-100 scale), and\u002For Upper limb dysfunction, and\u002For Cancer-related fatigue (as measured by FACIT-Fatigue). Able to understand and provide written informed consent.\n\nExclusion Criteria:\n\nDiagnosis of recurrent or metastatic breast cancer. Currently receiving active cancer treatment (chemotherapy, radiation for active disease, or immunotherapy).\n\nParticipation in another interventional trial targeting pain or rehabilitation within the past 3 months.\n\nPresence of severe comorbidities (e.g., uncontrolled cardiovascular disease, severe orthopedic or neurological conditions) that would preclude safe participation in physiotherapy.\n\nAny physical or psychological condition that, in the opinion of the investigator, would interfere with participation or adherence to the study protocol (e.g., severe cognitive impairment).\n\nPregnancy or breastfeeding.","ALL","18 Years","65 Years",{"count":67,"type":68},146,"ESTIMATED","INTERVENTIONAL",[71],"NA","This multi-center randomized controlled trial (RCT) evaluates the long-term (12-month) effectiveness of a standardized multidisciplinary physiotherapy program versus standard care on persistent pain, upper limb (UL) dysfunction, and cancer-related fatigue (CRF) in breast cancer survivors. The study also examines improvements in quality of life and psychological well-being. The standardized intervention combines specific exercise therapy, manual therapy, education, and mind-body interventions and is designed to produce sustained benefits beyond the acute rehabilitation phase.",[74,75],"Breast Cancer","Breast Cancer Female","2025-03-30",{"date":78,"type":79},"2025-04-06","ACTUAL",{"date":81,"type":68},"2025-04-23",{"date":83,"type":68},"2027-01-01",{"name":5,"class":6},1]