[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100420368":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":49,"centralContacts":54,"locations":60,"responsibleParty":79,"collaborators":36,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":85,"acronym":36,"eligibilityCriteria":86,"healthyVolunteers":83,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":36,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":36,"overallStatus":63,"whyStopped":36,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Henan Institute of Cardiovascular Epidemiology","OTHER",[8,15,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"CRIC+MFT","EXPERIMENTAL","CRIC :Twice daily for 12 weeks using an automated cuff device. Each 30-minute session consisted of 3 cycles of 6 min inflation (pressure individualized: resting SBP-based increments of +40\u002F+30\u002F+20 mmHg depending on baseline SBP level) followed by 4 min deflation (0 mmHg).\n\nMFT:Twice daily guided audio sessions (synchronized with CRIC timing) emphasizing focused attention on breath and bodily sensations to foster mindful awareness.",[13,14],"Device: CRIC","Behavioral: MFT",{"label":16,"type":10,"description":17,"interventionNames":18},"sham CRIC+MFT","Sham CRIC: Identical schedule and device; each cycle used fixed 5 min inflation at 60 mmHg (non-ischemic) followed by 5 min deflation.\n\nMFT: Twice daily guided audio sessions (synchronized with CRIC timing) emphasizing focused attention on breath and bodily sensations to foster mindful awareness.",[14,19],"Other: sham CRIC",{"label":21,"type":10,"description":22,"interventionNames":23},"CRIC+sham MFT","CRIC :Twice daily for 12 weeks using an automated cuff device. Each 30-minute session consisted of 3 cycles of 6 min inflation (pressure individualized: resting SBP-based increments of +40\u002F+30\u002F+20 mmHg depending on baseline SBP level) followed by 4 min deflation (0 mmHg).\n\nSham MFT: Twice daily equivalent-duration audio of looped neutral nature sounds (ocean waves, flowing water, birdsong) without mindfulness instructions.",[13,24],"Other: sham MFT",{"label":26,"type":27,"description":28,"interventionNames":29},"Sham CRIC+Sham MFT","PLACEBO_COMPARATOR","Sham CRIC: Identical schedule and device; each cycle used fixed 5 min inflation at 60 mmHg (non-ischemic) followed by 5 min deflation.\n\nSham MFT: Twice daily equivalent-duration audio of looped neutral nature sounds (ocean waves, flowing water, birdsong) without mindfulness instructions.",[19,24],[31,37,42,45],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"DEVICE","CRIC","Remote Ischemic Conditioning (CRIC): Twice daily for 12 weeks using an automated cuff device. Each 30-minute session consisted of 3 cycles of 6 min inflation (pressure individualized: resting SBP-based increments of +40\u002F+30\u002F+20 mmHg depending on baseline SBP level) followed by 4 min deflation (0 mmHg).",[9,21],null,{"type":38,"name":39,"description":40,"armGroupLabels":41,"otherNames":36},"BEHAVIORAL","MFT","Sham CRIC: Identical schedule and device; each cycle used fixed 5 min inflation at 60 mmHg (non-ischemic) followed by 5 min deflation.",[9,16],{"type":6,"name":43,"description":40,"armGroupLabels":44,"otherNames":36},"sham CRIC",[26,16],{"type":6,"name":46,"description":47,"armGroupLabels":48,"otherNames":36},"sham MFT","Sham MFT: Twice daily equivalent-duration audio of looped neutral nature sounds (ocean waves, flowing water, birdsong) without mindfulness instructions.",[21,26],[50],{"name":51,"affiliation":52,"role":53},"Muwei Li, MD","Chinese Academy of Medical Sciences, Fuwai Hospital","STUDY_CHAIR",[55],{"name":56,"role":57,"phone":58,"phoneExt":36,"email":59},"En Li","CONTACT","13525070525","1799077212@qq.com",[61],{"facility":62,"status":63,"city":64,"state":65,"zip":66,"country":67,"countryCode":68,"cosmosGeoPoint":69,"geoPoint":74,"contacts":75},"Fuwai central China Cardiovascular hospital","RECRUITING","Zhengzhou","Henan","450008","China","CN",{"type":70,"coordinates":71},"Point",[72,73],113.64861,34.75778,{"lat":73,"lon":72},[76],{"name":51,"role":57,"phone":77,"phoneExt":36,"email":78},"+8613838083966","lmw0207@163.com",{"type":80,"investigatorFullName":36,"investigatorTitle":36,"investigatorAffiliation":36,"oldNameTitle":36,"oldOrganization":36},"SPONSOR","100420368","long-term-of-remote-ischemic-preconditioning-and-mindfulness-in-patients-with-mild-hypertension-100420368",false,"NCT04753840","Long-term of Remote Ischemic Preconditioning and Mindfulness in Patients With Mild Hypertension","Inclusion Criteria:\n\n* Diagnosed patients with mild hypertension (SBP: 140\\~159mmHg; DBP: 90\\~99mmHg)\n\nExclusion Criteria:\n\n* Cannot tolerate RIPC\n* Non-essential hypertension\n* patients who have uncontrolled severe arrhythmia, diabetes, electrolyte disturbance\n* patients who have severe organic diseases such acute myocardial infarction, cardiac insufficiency, abnormal renal function, etc.","ALL","18 Years","80 Years",{"count":91,"type":92},400,"ESTIMATED","INTERVENTIONAL",[95],"NA","According to the latest survey data of China hypertension annual meeting, there are about 300 million patients with hypertension in China, with 10 million new cases of hypertension each year, and there is an obvious trend of younger people. In particular, young and middle-aged people are in a state of mild hypertension for a long time, which causes great pressure on health and medical treatment. At present, the main clinical measures for mild hypertension are to change their eating habits, quit smoking and alcohol, exercise and other lifestyle changes, as well as drug control. For most patients with mild hypertension, drug control is not the best choice. It has been reported that remote ischemic preconditioning (RIPC) may play an effective role in reducing blood pressure .The purpose of this study was to investigate the extent of long-term application of RIPC to reduce blood pressure in patients with mild hypertension.",[98],"Hypertension","2026-04-01",{"date":101,"type":102},"2026-04-06","ACTUAL",{"date":104,"type":102},"2021-07-03",{"date":106,"type":92},"2030-12-01",{"name":5,"class":6},1]