[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100534447":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":7,"responsibleParty":23,"collaborators":7,"id":25,"slug":26,"hasResults":27,"nctId":28,"briefTitle":29,"officialTitle":30,"acronym":7,"eligibilityCriteria":31,"healthyVolunteers":27,"sex":32,"minAge":33,"maxAge":34,"enrollmentInfo":35,"targetDuration":7,"studyType":38,"phases":7,"briefSummary":39,"conditions":40,"keywords":43,"overallStatus":46,"whyStopped":7,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":7},{"fullName":5,"class":6},"Istituto Ortopedico Rizzoli","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Stefano Zaffagnini, MD","Istituto Ortopedico Rizzoli - II Clinica Ortopedica e Traumatologica","PRINCIPAL_INVESTIGATOR",[14,18],{"name":10,"role":15,"phone":16,"phoneExt":7,"email":17},"CONTACT","0516366567","stefano.zaffagnini@ior.it",{"name":19,"role":15,"phone":20,"phoneExt":21,"email":22},"Roberta Licciardi, MSc","6366567","051","roberta.licciardi@ior.it",{"type":24,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100534447","long-term-outcome-evaluation-of-patients-undergoing-autologous-chondrocyte-transplantation-delivered-on-biomaterial-100534447",false,"NCT06238947","Long-term Outcome Evaluation of Patients Undergoing Autologous Chondrocyte Transplantation Delivered on Biomaterial","LONG-TERM EVALUATION OF OUTCOMES OF PATIENTS UNDERGOING AUTOLOGOUS CHONDROCYTE TRANSPLANTATION DELIVERED ON BIOMATERIAL (HYALOGRAFT C) Prospective Observational Study","Inclusion Criteria:\n\n* Patients who underwent autologous chondrocyte transplantation surgery delivered on biomaterial (Hyalograft C) from 1999 to 2006 at the Rizzoli Orthopaedic Institute who met the following criteria at the time of surgery:\n* Full-thickness chondral defects (Outerbridge grade III - IV) and osteochondral defects at the femoral condyles, trochlea, patella and tibial plateau.\n* Patients aged between 14 and 60 years at the time of surgery.\n* Male and female sex.\n\nExclusion Criteria:\n\n* Patients no longer available","ALL","14 Years","60 Years",{"count":36,"type":37},200,"ESTIMATED","OBSERVATIONAL","Chondro-Long study is prospective observational study for a long-term clinical evaluation (follow-up up to 25 years) in patients treated with autologous chondrocyte transplantation delivered on biomaterial for full-thickness chondral defects (Outerbridge grade III - IV) at the level of femoral condyles, trochlea, patella and tibial plateau.\n\nThe aim of the study is to collect long-term clinical data from the case series of patients surgically treated from 1999 to 2006 with autologous chondrocyte transplantation delivered on biomaterial for full-thickness chondral defects (Outerbridge grade III - IV) or osteochondral defects at the level of femoral condyles, trochlea, patella, and tibial plateau. The objective of the study is to demonstrate the efficacy of this long-term cartilage regeneration technique (follow-up up to 25 years) in improving patient symptomatology and functional capacity",[41,42],"Cartilage Injury","Cartilage Disease",[44,45],"autologous chondrocyte transplantation","osteochondral defects","NOT_YET_RECRUITING","2026-06-30",{"date":49,"type":50},"2026-07-01","ACTUAL",{"date":52,"type":37},"2026-09",{"date":54,"type":37},"2027-02",{"name":5,"class":6}]