[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641693":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":31,"responsibleParty":48,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Papa Giovanni XXIII Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients who underwent percutaneous cryoneurolysis for the Nuss procedure pain management",null,"All patients who underwent surgical correction of pectus excavatum via the Nuss procedure between July 1, 2022 and February 28, 2026 are considered eligible for enrollment. Additionally, for the prospective component, patients scheduled for surgery up to December 31, 2026 at the Pediatric Surgery department of our institution will be considered eligible.\n\nInclusion criteria:\n\nAge greater than 14 years. Patients who underwent percutaneous cryoneurolysis. Patients who underwent surgical correction of pectus excavatum according to the Nuss procedure.\n\nExclusion criteria:\n\nPatients who withhold consent to participate in the study, patients with pre-existing neurological conditions, and patients who do not attend the scheduled follow-up visits will be excluded from the study.",[13],"Diagnostic Test: Self-report Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) Questionnaire - Pediatric Quality of Life Inventory (PedsQL™) Questionnaire - Patient Self-Assessment Sensory Scale",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Self-report Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) Questionnaire - Pediatric Quality of Life Inventory (PedsQL™) Questionnaire - Patient Self-Assessment Sensory Scale","Assessment tools include validated questionnaires - the S-LANSS (Self-report Leeds Assessment of Neuropathic Symptoms and Signs, range 0-24, higher scores indicating greater likelihood of neuropathic pain) and the PedsQL™ (Pediatric Quality of Life Inventory, v4.0, Adolescent\u002FYoung Adult Report, range 0-100, higher scores indicating better health-related quality of life) - together with the Patient Self-Assessment Sensory Scale (range 0-10, 0 indicating no sensitivity and 10 indicating normal sensitivity) and a structured physical examination of thoracic sensitivity. These tools are administered at pre-specified follow-up timepoints. The physical examination assesses four sensory modalities corresponding to specific afferent fibre classes of the intercostal nerves: cold thermal sensation (Aδ fibres, ice-water contact, 4-10°C), warm thermal sensation (C fibres, \\~40°C water), light touch (Aβ fibres, camel-hair brush), and pressure sensitivity (Aβ fibres, Von Frey filament 5.07\u002F10g)",[9],[21],{"name":22,"affiliation":23,"role":24},"Ezio Bonanomi, MD","Department of Anesthesia and Intensive Care, Paediatric Anesthesiology and Intensive Care Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.","STUDY_CHAIR",[26],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Stefano Mariconti, MD","CONTACT","0039 + 0352675149","smariconti@asst-pg23.it",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"ASST Papa Giovanni XXIII","RECRUITING","Bergamo","BG","24127","Italy","IT",{"type":41,"coordinates":42},"Point",[43,44],9.66721,45.69601,{"lat":44,"lon":43},[47],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Stefano Mariconti","Consultant Anesthesiologist","100641693","long-term-safety-of-preoperative-percutaneous-intercostal-cryoneurolysis-100641693",false,"NCT07657845","Long Term Safety of Preoperative Percutaneous Intercostal Cryoneurolysis","Long Term Safety of Preoperative Percutaneous Intercostal Cryoneurolysis: Neuropathic Pain, Quality of Life and Sensory Recovery in a Paediatric Cohort Following Pectus Excavatum Repair","CRYOFUP","Inclusion Criteria:\n\n* Patients who underwent percutaneous cryoneurolysis.\n* Patients who underwent surgical correction of pectus excavatum according to the Nuss procedure.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* Peripheral nervous system disorders\n* Age \\\u003C 14 years\n* Failure to attend scheduled follow-up visits","ALL","14 Years",{"count":63,"type":64},50,"ESTIMATED","OBSERVATIONAL","Follow up of patients who underwent percutaneous cryoneurolysis for pectus excavatum repair (the Nuss procedure) pain management",[68,69],"Cryo Analgesia","Pectus Surgery",[71,72,73,74,75,76,77,78],"follow up","lanss","neuropathy","chronic pain","cpsp","neuropathic pain","sensitivity recovery","PedsQL","2026-06-17",{"date":81,"type":82},"2026-06-22","ACTUAL",{"date":84,"type":82},"2025-02-02",{"date":86,"type":64},"2029-01-15",{"name":5,"class":6},1]