[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499671":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":32,"centralContacts":50,"locations":58,"responsibleParty":80,"collaborators":10,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":10,"eligibilityCriteria":88,"healthyVolunteers":84,"sex":89,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":10,"studyType":95,"phases":10,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":105,"whyStopped":10,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"PT. Prodia Stem Cell Indonesia","INDUSTRY",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Conditioned Medium (CM)",null,"2 ml volume of Conditioned Medium derived Umbilical Cord Mesenchymal Stem Cell injected into peribulbar",[13],"Biological: Conditioned Medium (CM)",{"label":15,"type":10,"description":16,"interventionNames":17},"UC-MSC + NaCl","1.8 ml cell preparations are suspended in physiological NaCl until it reaches a 2 ml volume of cell suspension. Umbilical Cord Mesenchymal Stem Cell (UC-MSC) suspension injected into peribulbar",[18],"Biological: Umbilical Cord Mesenchymal Stem Cell (UC-MSC)",{"label":20,"type":10,"description":21,"interventionNames":22},"UC-MSC+CM","1.8 ml cell preparations are suspended in Conditioned Medium (CM) until it reaches a total of 2 ml volume of cell suspension. Umbilical Cord Mesenchymal Stem Cell (UC-MSC) + Conditioned Medium (CM) suspension injected into peribulbar",[13,18],[24,28],{"type":25,"name":9,"description":26,"armGroupLabels":27,"otherNames":10},"BIOLOGICAL","Conditioned Medium (CM) injected by peribulbar",[9,20],{"type":25,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"Umbilical Cord Mesenchymal Stem Cell (UC-MSC)","Umbilical Cord Mesenchymal Stem Cell (UC-MSC) injected by peribulbar",[15,20],[33,37,41,45,48],{"name":34,"affiliation":35,"role":36},"dr. Muhammad B Sasongko, Sp.M, M.Epid, PhD","Gadjah Mada University, Faculty of Medicine","PRINCIPAL_INVESTIGATOR",{"name":38,"affiliation":39,"role":40},"dr Cosmos O Mangunsong, Sp.M","Jakarta Eye Center","STUDY_DIRECTOR",{"name":42,"affiliation":43,"role":44},"dr. Rifa Widyaningrum, M.Sc, PhD","Sardjito Hospital","STUDY_CHAIR",{"name":46,"affiliation":47,"role":44},"Rima Haifa, S.Si","Prodia StemCell Indonesia",{"name":49,"affiliation":47,"role":44},"Marsya N Kirana, S.T., M.Sc",[51,55],{"name":34,"role":52,"phone":53,"phoneExt":10,"email":54},"CONTACT","+62 811-293-476","mb.sasongko@ugm.ac.id",{"name":56,"role":52,"phone":10,"phoneExt":10,"email":57},"Dr. Cynthia R Sartika, M.Si","cynthia.sartika@prostem.co.id",[59,71],{"facility":60,"status":10,"city":61,"state":62,"zip":10,"country":63,"countryCode":64,"cosmosGeoPoint":65,"geoPoint":70,"contacts":10},"Jakarta Eye Center Hospital","Jakarta","DKI Jakarta","Indonesia","ID",{"type":66,"coordinates":67},"Point",[68,69],106.84513,-6.21462,{"lat":69,"lon":68},{"facility":43,"status":10,"city":72,"state":73,"zip":74,"country":63,"countryCode":64,"cosmosGeoPoint":75,"geoPoint":79,"contacts":10},"Yogyakarta","Special Region","55284",{"type":66,"coordinates":76},[77,78],110.36472,-7.80139,{"lat":78,"lon":77},{"type":81,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100499671","long-term-safety-of-uc-msc-transplantation-in-patients-with-retinitis-pigmentosa-100499671",false,"NCT05786287","Long-term Safety of UC-MSC Transplantation in Patients With Retinitis Pigmentosa","Long-term Safety of Umbilical Cord-Mesenchymal Stem Cell (UC-MSC) Transplantation in Patients With Retinitis Pigmentosa","Inclusion Criteria:\n\n* Visual field defects at the initial examination with Humphrey perimetry are between 25% to 50%\n* Willing to sign informed consent as research subjects\n* Willing to do the peribulbar injection with mesenchymal stem cells isolated from umbilical cord tissue\n* Willing to do visual field checks with Humphrey's perimetry, vision tests with Snellen boards, Optical Coherent Tomography (OCT) examinations, electroretinogram examinations and fill out a quality of life questionnaire\n\nExclusion Criteria:\n\n* Pregnant or nursing women\n* Positive result of HIV test\n* Have a history of eye tumours\n* In the immunosuppressive treatment or other drugs that can affect the growth of transplanted stem cells\n* Have another eye disease such as diabetic retinopathy, uveitis, cataract, and glaucoma\n* Do not come to control according to the schedule determined by the researcher (loss to follow up)","ALL","18 Years","65 Years",{"count":93,"type":94},18,"ESTIMATED","OBSERVATIONAL","The study will perform to follow-up UC-MSCs and CM transplantation. 18 patients will be called back to be examined after 5 years of UC-MSC and\u002For CM transplantation.",[98],"Retinitis Pigmentosa",[100,101,102,103,104],"Allogeneic Mesenchymal Stem Cell","Umbilical Cord Mesenchymal Stem Cell","Conditioned Medium","Allogeneic Umbilical Cord Mesenchymal Stem Cell","Safety","NOT_YET_RECRUITING","2026-02-23",{"date":108,"type":109},"2026-02-25","ACTUAL",{"date":111,"type":94},"2026-05",{"date":113,"type":94},"2027-09",{"name":5,"class":6},2]