[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608983":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":22,"responsibleParty":47,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":10,"maxAge":10,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":25,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Universitat Internacional de Catalunya","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"'atients previously enrolled in the PER-ECL-2019-05 trial",null,"Initially, 36 patients with advanced peri-implantitis were enrolled in a randomized clinical trial evaluating the clinical, radiographic and patient-related outcomes of reconstructive therapy following a non-surgical phase of peri-implantitis treatment compared to non-surgical treatment alone (PER-ECL-2019-05) .At the study conclusion 34 patients were re-evaluated and 2 patients were excluded from the study",[13],{"name":14,"affiliation":5,"role":15},"CRISTINA VALLES CS VALLES, PhD","PRINCIPAL_INVESTIGATOR",[17],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},"cristina valles cv cristina valles DDS, MSc, PhD, PhD","CONTACT","93 504 20 00","cristinavallveg@uic.es",[23,41],{"facility":24,"status":25,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Hospital Universitari General de Catalunya","RECRUITING","Sant Cugat del Vallès","Bacelona","08195","Spain","ES",{"type":32,"coordinates":33},"Point",[34,35],2.08611,41.47063,{"lat":35,"lon":34},[38],{"name":39,"role":19,"phone":20,"phoneExt":40,"email":21},"cristina valles, PhD","+34",{"facility":42,"status":25,"city":26,"state":43,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":44,"geoPoint":46,"contacts":10},"Clinica Universitaria ́̀ d'Odontologia - UIC Barcelona at the Periodontology Department","Barcelona",{"type":32,"coordinates":45},[34,35],{"lat":35,"lon":34},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Ramón Pons Calabuig","dds ms","100608983","long-term-stability-of-peri-implantitis-treatments-a-3-year-clinical-evaluation-100608983",false,"NCT07208643","Long-term Stability of Peri-implantitis Treatments: a 3-year Clinical Evaluation","Inclusion Criteria:\n\n* 1\\. Patiens previously enrolled in the randomized clinical trial PER-ECL-2019-05, which included 36 patients with advanced peri-implantitis.\n\n  2\\. Completion of the original study protocol, including either reconstructive surgical therapy following a non-surgical phase or non-surgical therapy alone.\n\n  3.Signed informed consent for participation in the follow-up assessment.\n\nExclusion Criteria:\n\n* 1.Did not complete the original clinical trial protocol (PER-ECL-2019-05) or withdrew before final evaluation.\n\n  2.Had the implant removed due to complications unrelated to peri-implantitis progression.\n\n  3.Have developed systemic diseases or conditions (e.g., uncontrolled diabetes, immunosuppression, malignancy) that may affect periodontal or peri-implant tissue healing or confound clinical outcomes.\n\n  4.Are currently undergoing antibiotic or antiresorptive therapy (e.g., bisphosphonates) that could interfere with bone metabolism.\n\n  5.Are pregnant or breastfeeding at the time of the follow-up visit. 6.Are unwilling or unable to attend the clinical follow-up appointment or provide informed consent.","ALL",{"count":59,"type":60},34,"ESTIMATED","3 Years","OBSERVATIONAL","This prospective study will include patients previously enrolled in the PER-ECL-2019-05 trial who attend the Department of Periodontology (CUO) for maintenance therapy or treatment of periodontal and\u002For peri-implant diseases, provided they meet the inclusion criteria.\n\nInitially, 36 patients with advanced peri-implantitis were enrolled in a randomized clinical trial evaluating the clinical, radiographic and patient-related outcomes of reconstructive therapy following a non-surgical phase of peri-implantitis treatment compared to non-surgical treatment alone (PER-ECL-2019-05) (10).\n\nAt the study conclusion 34 patients were re-evaluated and 2 patients were excluded from the study (10).\n\nIn the original study, adult patients presenting at least one titanium implant diagnosed with peri-implantitis were identified among patients referred to the Department of Periodontology of UIC between January 2020 and October 2022. Peri-implantitis was diagnosed following the case definition of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions (11) that is, PPD ≥ 6 mm combined with bleeding on probing (BOP) and\u002For suppuration (SUP), together with progressive bone loss in relation to the radiographic bone level assessment. In those cases where initial radiograph was unavailable, the definition of a peri-implantitis case was based on radiographic evidence of bone level ≥3 mm apical to the most coronal portion of the intra-osseous part of the implant (12).\n\nAt the outset of the original study, participants were randomly assigned to one of two groups:\n\nThe first group received only non-surgical therapy for peri-implantitis, while the second group underwent a non-surgical phase followed by reconstructive surgical treatment. This design allowed for direct comparison of the clinical, radiographic, and patient-centered outcomes between the two treatment modalities. Both groups were managed and evaluated according to standardized protocols, ensuring consistency and reliability of the results at 12 months .\n\nPatients who have not returned to the Department will be contacted by telephone and invited to participate through the academic office.\n\nAt 36 months, a single follow-up will be carried out including:\n\nA detailed clinical examination. A standardized radiographic assessment.",[65],"Peri-implantitis",[65,67,68,69,70,71],"Non-surgical therapy","Reconstructive therapy","Maintenance therapy","Prospective study","flapless treatment","2026-04-27",{"date":74,"type":75},"2026-04-28","ACTUAL",{"date":77,"type":75},"2026-04-01",{"date":79,"type":60},"2026-05-01",{"name":49,"class":6},2]