[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606366":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":28,"locations":34,"responsibleParty":53,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":10,"enrollmentInfo":65,"targetDuration":10,"studyType":68,"phases":10,"briefSummary":69,"conditions":70,"keywords":10,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Medtronic Vascular","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Symplicity RDN + SOC",null,"Medicare patients on a stable antihypertension medication regimen and received RDN with a Symplicity RDN system",[13],"Device: Renal Denervation (Symplicity Spyral™)",{"label":15,"type":10,"description":16,"interventionNames":10},"SOC","Medicare patients on a stable antihypertension medication regimen",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"DEVICE","Renal Denervation (Symplicity Spyral™)","Symplicity Spyral™ multi-electrode renal denervation system",[9],[24],{"name":25,"affiliation":26,"role":27},"Eric A Secemsky, MD, MSc","Beth Israel Deaconess Medical Center","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Kael Wherry, PhD, MS","CONTACT","612-229-0714","kael.wherry@medtronic.com",[35],{"facility":26,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Boston","Massachusetts","02215","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-71.05977,42.35843,{"lat":46,"lon":45},[49],{"name":50,"role":31,"phone":51,"phoneExt":10,"email":52},"Eric A. Secemsky, MD, MSc","617-632-7753","esecemsk@bidmc.harvard.edu",{"type":54,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100606366","longitudinal-real-world-clinical-outcomes-study-on-symplicity-renal-denervation-100606366",false,"NCT07174622","Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation","Real-world Clinical Outcomes in Medicare Patients With Hypertension Treated With Symplicity Renal Denervation Plus Standard of Care Versus Standard of Care in Integrated EHR and Claims Data","SPYRAL CARE","Inclusion Criteria:\n\n* Enrolled in a Medicare plan\n* Diagnosis of uncontrolled hypertension\n* On a stable regimen of antihypertensive therapy\n\nExclusion Criteria:\n\n* A prior RDN procedure\n* Diagnosis of secondary hypertension\n* Any condition for which RDN is contraindicated","ALL","18 Years",{"count":66,"type":67},1000,"ESTIMATED","OBSERVATIONAL","This observational study will assess the long-term effectiveness of the RDN procedure for lowering blood pressure in Medicare patients with uncontrolled hypertension. This research will be conducted using de-identified electronic health records (EHR) and administrative health insurance claims data. Patients are enrolled through the submission of claims or encounter data to CMS.",[71,72,73],"Hypertension","Cardiovascular Diseases","Vascular Diseases","2026-04-21",{"date":76,"type":77},"2026-04-22","ACTUAL",{"date":79,"type":77},"2025-10-28",{"date":81,"type":67},"2029-06",{"name":5,"class":6},1]