[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522495":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":27,"responsibleParty":92,"collaborators":95,"id":99,"slug":100,"hasResults":101,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":101,"sex":107,"minAge":108,"maxAge":10,"enrollmentInfo":109,"targetDuration":112,"studyType":113,"phases":10,"briefSummary":114,"conditions":115,"keywords":118,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},{"fullName":5,"class":6},"Institut de Recerca Biomèdica de Lleida","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"post-ICU with ARDS",null,"Patients admitted to the ICU who have developed Acute Respiratory Distress Syndrome (ARDS), as defined according the new 2023 guidelines (Matthay et.al, 2023)",{"label":13,"type":10,"description":14,"interventionNames":10},"post-ICU without ARDS","Patients admitted to the ICU who have suffered a severe pneumonia, needing advanced respiratory support, but without developing ARDS according to the new 2023 guidelines.",[16],{"name":17,"affiliation":5,"role":18},"Jessica González Gutiérrez, MD, PhD","PRINCIPAL_INVESTIGATOR",[20,24],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","973 70 53 72","jgonzalezgutierrez88@gmail.com",{"name":25,"role":21,"phone":22,"phoneExt":10,"email":26},"Ferran Barbé Illa, MD, PhD","febarbe.lleida.ics@gencat.cat",[28,53,70],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Hospital de Tortosa Verge de la Cinta","RECRUITING","Tortosa","Tarragona","43500","Spain","ES",{"type":37,"coordinates":38},"Point",[39,40],0.5216,40.81249,{"lat":40,"lon":39},[43,47,48,51],{"name":44,"role":21,"phone":45,"phoneExt":10,"email":46},"Ferran Roche Campo, MD, PhD","+34 977519100","ferranroche@gmail.com",{"name":44,"role":18,"phone":10,"phoneExt":10,"email":10},{"name":49,"role":50,"phone":10,"phoneExt":10,"email":10},"Luis Adolfo Urrelo Cerron, MD","SUB_INVESTIGATOR",{"name":52,"role":50,"phone":10,"phoneExt":10,"email":10},"Neus Bofill Soler, MD",{"facility":54,"status":30,"city":55,"state":10,"zip":56,"country":34,"countryCode":35,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Hospital Universitari Arnau de Vilanova","Lleida","25198",{"type":37,"coordinates":58},[59,60],0.62218,41.61674,{"lat":60,"lon":59},[63,66,67,68],{"name":64,"role":21,"phone":65,"phoneExt":10,"email":23},"Jessica González Guitérrez, MD, PhD","+34 973705372",{"name":25,"role":21,"phone":65,"phoneExt":10,"email":26},{"name":64,"role":18,"phone":10,"phoneExt":10,"email":10},{"name":69,"role":50,"phone":10,"phoneExt":10,"email":10},"Jesús Caballero Lopez, MD",{"facility":71,"status":30,"city":32,"state":10,"zip":72,"country":34,"countryCode":35,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"Hospital Universitari Joan XXIII","43005",{"type":37,"coordinates":74},[75,76],1.24544,41.11905,{"lat":76,"lon":75},[79,83,86,88,90],{"name":80,"role":21,"phone":81,"phoneExt":10,"email":82},"Monica Magret Iglesias, MD","+34 977295800","mmagret@gmail.com",{"name":84,"role":21,"phone":81,"phoneExt":10,"email":85},"Sara Manrique Moreno, MD","smanriquemoreno@gmail.com",{"name":87,"role":50,"phone":10,"phoneExt":10,"email":10},"Salvador Perelló Aragonés, MD",{"name":89,"role":50,"phone":10,"phoneExt":10,"email":10},"Monica Magret Iglesias",{"name":91,"role":50,"phone":10,"phoneExt":10,"email":10},"Sara Manrique Moreno",{"type":18,"investigatorFullName":93,"investigatorTitle":94,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Jessica González Gutiérrez MD, PhD","Medical Doctor, Doctor of Philosophy",[96],{"name":97,"class":98},"Instituto de Salud Carlos III","OTHER_GOV","100522495","longitudinal-recovery-trajectories-after-an-acute-respiratory-distress-syndrome-a-new-understanding-100522495",false,"NCT06083363","Longitudinal Recovery Trajectories After an Acute Respiratory Distress Syndrome, a New Understanding","Longitudinal Recovery Trajectories After an Acute Respiratory Distress Syndrome, a New Understanding. The TENACITY Study","TENACITY","Inclusion Criteria:\n\n* Male and female patients aged ≥18 years\n* Admission to the ICU\n* Diagnosis of severe pneumonia and\u002For diagnosis of acute respiratory distress syndrome (ARDS) based on the 2023 definition due to any origin (infectious and non-infectious)\n\nExclusion Criteria:\n\n* Life expectancy less than a year\n* Transfer to another hospital during hospitalization or follow-up\n* Stay in palliative care\n* Severe mental disability that makes it impossible to carry out pulmonary function tests during follow-up","ALL","18 Years",{"count":110,"type":111},246,"ESTIMATED","12 Months","OBSERVATIONAL","COVID-19 resulted in the largest cohort of critical illness survivors in history, heightened awareness of the importance of the respiratory sequelae after an acute distress respiratory syndrome (ADRS). Despite the advancement of acute-phase ARDS management, it is unknown whether there are differences in the longitudinal recovery trajectories between patients with post-ARDS due to COVID-19 and due to other causes. The main objective of the study is to identify risk factors of pulmonary sequela (lung diffusing capacity) at long-term follow-up in survivors of ARDS. The investigators are also interested in describing the long-term longitudinal recovery trajectories at a multi-dimensional level (symptoms, quality of life, neurocognitive, other lung function parameters, exercise capacity, chest imaging and molecular profiles) of ARDS survivors, and compared between ARDS caused by COVID-19. The ultimate goal is to understand the pathobiological mechanisms associated with a severe lung injury at the long term, allowing the introduction of clinical guidelines for the management of post-ARDS patients and the assignment of personalized interventions.",[116,117],"ARDS","ARDS Disease Progression",[116,119],"ICU","2024-03-05",{"date":122,"type":123},"2024-03-06","ACTUAL",{"date":125,"type":123},"2023-06-29",{"date":127,"type":111},"2026-12-31",{"name":5,"class":6},3]