[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100523653":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":10,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":10,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":10,"overallStatus":40,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Università Vita-Salute San Raffaele","OTHER",[8,12,17,21],{"label":9,"type":10,"description":11,"interventionNames":10},"infertile women (unexplained, tubal, mild male factor)",null,"women belonging to couples selected for homologous IVF due to an unexplained, tubal or mild male factor",{"label":13,"type":10,"description":14,"interventionNames":15},"fertile women","women without any infertility history who are attempting to conceive naturally",[16],"Genetic: search for epigenetic profile of infertility",{"label":18,"type":10,"description":19,"interventionNames":20},"infertile women (ovarian factor)","women selected for homologous IVF for different reason og chohort 1",[16],{"label":22,"type":10,"description":23,"interventionNames":24},"recurrent pregnancy loss","women affected by idiopathic recurrent pregnancy loss",[16],[26],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":10},"GENETIC","search for epigenetic profile of infertility","examine the epigenetic profile of DNA extracted from MGCs and blood sample",[13,18,22],[32],{"name":33,"role":34,"phone":35,"phoneExt":10,"email":36},"Valeria Stella Vanni","CONTACT","+393476309895","vanni.valeria@hsr.it",[38],{"facility":39,"status":40,"city":41,"state":10,"zip":10,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Università Vita Salute San Raffaele","RECRUITING","Milan","Italy","IT",{"type":45,"coordinates":46},"Point",[47,48],12.59836,42.78235,{"lat":48,"lon":47},[51,52],{"name":33,"role":34,"phone":35,"phoneExt":10,"email":36},{"name":53,"role":54,"phone":10,"phoneExt":10,"email":10},"Sara D'Alessandro","SUB_INVESTIGATOR",{"type":56,"investigatorFullName":33,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Doctor","100523653","looking-for-a-blood-epigenetic-signature-to-predict-female-infertility-100523653",false,"NCT06098495","Looking for a Blood Epigenetic Signature to Predict Female Infertility","FIB_CARIPLO","Inclusion Criteria:\n\n* 18\\\u003C age \\\u003C43, Infertile woman undergoing ART, recurrent pregnancy loss\n\nExclusion Criteria:\n\n* age \\\u003C 18 or \\> 44, previous ovarian surgery, severe male factor infertility",true,"FEMALE","18 Years","43 Years",{"count":70,"type":71},1456,"ESTIMATED","OBSERVATIONAL","The present research project aims to study the DNAm mechanisms underlying the reduction of fertility due to the progressive depletion of oocyte quality. Specifically, our project aims to build an epigenetic clock for MGCs by using outcomes that are certainly related to female fertility. The validation of such findings will be carried out on peripheral blood in order to guarantee its non-invasiveness and allow for any clinical transferability. In order to identify a blood epigenetic signature able to predict female infertility, we planned to explore the problem from different points of view by conducting several studies in different settings.",[75],"Female Infertility","2023-10-18",{"date":78,"type":79},"2023-10-24","ACTUAL",{"date":81,"type":79},"2023-10-16",{"date":83,"type":71},"2026-10-16",{"name":5,"class":6},1]