[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596075":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":21,"locations":27,"responsibleParty":39,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":10,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":10,"enrollmentInfo":51,"targetDuration":10,"studyType":54,"phases":10,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Gazi University","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"Group 1",null,"Followed using Bispectral Index (BIS) with 4% Sevoflurane and fresh gas flow set at 0.5 L\u002Fmin",{"label":13,"type":10,"description":14,"interventionNames":10},"Group 2","Followed using Minimum Alveolar Concentration (MAC) with 4% Sevoflurane and fresh gas flow set at 0.5 L\u002Fmin",{"label":16,"type":10,"description":17,"interventionNames":10},"Group 3","Followed using BIS with 4% Sevoflurane and fresh gas flow set at 1 L\u002Fmin",{"label":19,"type":10,"description":20,"interventionNames":10},"Group 4","Followed using MAC with 4% Sevoflurane and fresh gas flow set at 1 L\u002Fmin",[22],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Çağrı Özdemir","CONTACT","+905544239196","cagriozdemir@gazi.edu.tr",[28],{"facility":29,"status":30,"city":31,"state":10,"zip":10,"country":32,"countryCode":10,"cosmosGeoPoint":33,"geoPoint":38,"contacts":10},"Gazi University Faculty of Medicine","RECRUITING","Ankara","Turkey (Türkiye)",{"type":34,"coordinates":35},"Point",[36,37],32.85427,39.91987,{"lat":37,"lon":36},{"type":40,"investigatorFullName":23,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","asst. prof.","100596075","low-flow-anesthesia-and-open-heart-surgery-100596075",false,"NCT07040735","Low-Flow Anesthesia and Open-Heart Surgery","The Effect of Low-Flow Anesthesia on Hemodynamics in Open-Heart Surgery","Inclusion Criteria:\n\n-≥18 years and scheduled for open-heart surgery patients\n\n-ASA I-II-III-IV physical class\n\nExclusion Criteria:\n\n* Emergency cases\n* Patients under 18 years of age\n* Patients who have had open heart surgery before\n* Patients for whom the use of inhaled anesthetic agents is contraindicated\n* Patients who do not sign a voluntary consent form","ALL","18 Years",{"count":52,"type":53},80,"ESTIMATED","OBSERVATIONAL","Low-flow anesthesia (LFA) is a technique in which at least 50% of the exhaled air, after carbon dioxide absorption, is mixed with a certain amount of fresh gas and returned to the patient during the next inspiration. In 1974, R. Virtue defined minimal flow anesthesia (MFA) as 0.5 L\u002Fmin. In 1984, Baker and Simionescu classified LFA as 0.5-1 L\u002Fmin and MFA as 0.25-0.5 L\u002Fmin. The aim of this study is to investigate whether there are hemodynamic differences between open-heart surgery cases performed with LFA at different fresh gas flow rates.",[57,58,59],"Low-flow Anesthesia","Hemodynamics","Open-heart Surgery",[61,58,62],"Low-flow anesthesia","Open-heart surgery","2026-05-22",{"date":65,"type":66},"2026-05-27","ACTUAL",{"date":68,"type":66},"2025-07-01",{"date":70,"type":53},"2026-09-23",{"name":23,"class":6},1]