[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636982":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":23,"responsibleParty":46,"collaborators":48,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":18,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":18,"enrollmentInfo":61,"targetDuration":18,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":25,"whyStopped":18,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"University of Alicante","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Power training group","EXPERIMENTAL","The intervention consists of a supervised power-oriented resistance training program for older men with metastatic prostate cancer undergoing androgen deprivation therapy (ADT). Participants will complete 2 sessions per week over 24 weeks.\n\nTraining focuses on improving muscle power through exercises performed at moderate intensity (40-50% 1RM), emphasizing a fast concentric phase and controlled eccentric phase. Multi-joint functional exercises targeting major muscle groups are included to enhance strength, balance, and daily functional performance.\n\nTraining volume is low-to-moderate, and participants do not train to muscular failure, allowing maintenance of movement velocity and reducing fatigue. Adequate rest periods are provided between sets.\n\nThe program is adapted to the clinical characteristics of the population, minimizing mechanical stress while promoting neuromuscular improvements. It is designed to be safe, feasible, and well-tolerated.",[13],"Other: Power training group",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","Participants will continue with their usual care and will receive standardized information and guidance on how to remain physically active at home.",null,[20],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":18},"The intervention consists of a supervised power-oriented resistance training program for older men with prostate cancer undergoing androgen deprivation therapy (ADT). Participants will complete 2 sessions per week over 24 weeks. Training focuses on improving muscle power through exercises performed at moderate intensity (40-50% 1RM), emphasizing a fast concentric phase and controlled eccentric phase. Multi-joint functional exercises targeting major muscle groups are included to enhance strength, balance, and daily functional performance. Training volume is low-to-moderate, and participants do not train to muscular failure, allowing maintenance of movement velocity and reducing fatigue. Adequate rest periods are provided between sets. The program is adapted to the clinical characteristics of the population, minimizing mechanical stress while promoting neuromuscular improvements. It is designed to be safe, feasible, and well-tolerated, with the aim of improving functional capacity.",[9],[24],{"facility":5,"status":25,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"RECRUITING","San Vicent del Raspeig","Alicante","03690","Spain","ES",{"type":32,"coordinates":33},"Point",[34,35],-0.5255,38.3964,{"lat":35,"lon":34},[38,43],{"name":39,"role":40,"phone":41,"phoneExt":18,"email":42},"Sergio Sebastia-Amat, PhD","CONTACT","0034 965903713","sergio.sebastia@ua.es",{"name":44,"role":45,"phone":18,"phoneExt":18,"email":18},"SERGIO SEBASTIA-AMAT, PhD","PRINCIPAL_INVESTIGATOR",{"type":47,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[49],{"name":50,"class":51},"Hospital General Universitario Dr. Balmis de Alicante","UNKNOWN","100636982","low-to-moderate-load-power-training-for-men-with-metastatic-prostate-cancer-100636982",false,"NCT07572760","Low to Moderate Load Power Training for Men With Metastatic Prostate Cancer.","Low to Moderate Load Power Training as an Exercise Intervention for Men With Metastatic Prostate Cancer Undergoing Androgen Deprivation Therapy.","Inclusion Criteria:\n\n* Histopathologically confirmed diagnosis of prostate adenocarcinoma.\n\n  • Metastatic hormone-sensitive prostate cancer (mHSPC), defined as:\n* Presence of metastases at initial diagnosis (synchronous mHSPC), or\n* Development of metastatic disease following prior treatment with curative intent (surgery and\u002For radiotherapy) (metachronous mHSPC).\n\n  * Evidence of progression to castration-resistant prostate cancer (CRPC).\n  * Ongoing treatment with a doublet regimen consisting of standard androgen deprivation therapy (ADT) in combination with an androgen receptor signaling inhibitor (ARSI), initiated prior to study enrollment.\n  * Receipt of bone-protective therapy, including calcium and vitamin D supplementation in combination with bisphosphonates.\n  * Presence of metastatic involvement limited to bone and\u002For lymph nodes.\n  * Functionally independent in activities of daily living.\n\nExclusion Criteria:\n\n* Evidence of visceral metastatic disease.\n* Current or prior treatment with a triplet regimen that includes chemotherapy.\n* History of pathological fracture.","MALE","50 Years",{"count":62,"type":63},66,"ESTIMATED","INTERVENTIONAL",[66],"NA","The goal of this clinical trial is to learn if a low to moderate load power training program is feasible and effective for improving fitness and quality of life of people with prostate cancer under androgen suppression therapy and bone or lymph node metastasis. The main questions it aims to answer are:\n\n* Does a low to moderate load power training program improve quality of life in people with metastatic prostate cancer under androgen deprivation therapy?\n* Does a low to moderate load power training program improve power, strength, endurance, and balance in people with metastatic prostate cancer under androgen deprivation therapy?\n\nResearchers will compare the exercise program with routine care to see if power training works to improve common physical side effects of androgen suppression therapy in patients with metastatic prostate cancer.\n\nParticipants will:\n\n* Participate in a supervised exercise program twice a week for 6 months or maintain routine care.\n* Perform fitness tests and questionnaires about quality of life and mental health.\n* Those who take part in the exercise program will also perform semi-structured in-depth interviews after the end of the program.",[69],"Prostatic Neoplasms",[71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,69,86,87,88,89,90,91,92,93],"Prostate cancer","Strength training","Power training","Quality of life","Mental health","Functional capacity","Exercise","Prostatic","Neoplasm","Androgen","Deprivation","Genital Neoplasms, Male","Urogenital Neoplasms","Genital Diseases","Urogenital Diseases","Motor Activity","Movement","Musculoskeletal Physiological Phenomena","Musculoskeletal and Neural Physiological Phenomena","Metastasis","Metastatic prostate cancer","Androgen deprivation","Testosterone","2026-04-30",{"date":96,"type":97},"2026-05-07","ACTUAL",{"date":99,"type":97},"2024-04-10",{"date":101,"type":63},"2026-12-10",{"name":5,"class":6},1]