[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622068":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":41,"responsibleParty":64,"collaborators":24,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":24,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":24,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":24,"overallStatus":44,"whyStopped":24,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Miami","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Low-Load Resistance Training","ACTIVE_COMPARATOR","Participants will receive low-load resistance training, twice per week for at least 24 sessions for up to 12 weeks.",[13],"Behavioral: Low-Load Resistance Training",{"label":15,"type":10,"description":16,"interventionNames":17},"High-Load Resistance Training","Participants will receive high-load resistance training, twice per week for at least 24 sessions for up to 12 weeks.",[18],"Behavioral: High-Load Resistance Training",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using three sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using four sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.",[15],[29],{"name":30,"affiliation":5,"role":31},"Joseph F. Signorile, PhD","PRINCIPAL_INVESTIGATOR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":24,"email":37},"Ethan J Elway, MS","CONTACT","3052844173","exe453@miami.edu",{"name":30,"role":35,"phone":39,"phoneExt":24,"email":40},"3052843105","jsignorile@miami.edu",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Laboratory of Neruomuscular Research and Active Aging","RECRUITING","Coral Gables","Florida","33147","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-80.26838,25.72149,{"lat":54,"lon":53},[57,60,63],{"name":58,"role":35,"phone":59,"phoneExt":24,"email":37},"Ethan Elway, MS","305-284-4173",{"name":30,"role":35,"phone":39,"phoneExt":61,"email":62},"Signorile","JSIGNORILE@MIAMI.EDU",{"name":30,"role":31,"phone":24,"phoneExt":24,"email":24},{"type":31,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Joseph Signorile","Professor","100622068","low-versus-high-load-training-and-parkinsons-disease-100622068",false,"NCT07378813","Low Versus High Load Training and Parkinson's Disease","Comparison of Changes in Neuromuscular and Functional Performance Due to Resistance Training With Low-Load or High-Load in Persons With Parkinson's Disease.","Inclusion Criteria:\n\n* Parkinson's Disease Hoehn \\& Yahr Stages 1-3\n* Able to walk 50m unassisted\n* Able to understand and communicate in English\n* A Montreal Cognitive Assessment (MoCA) score above 18\n\nExclusion Criteria:\n\n* Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program\n* Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness\n* Unresolved injury or surgery to the upper or lower limbs that prevents weight training.","ALL","50 Years","85 Years",{"count":78,"type":79},60,"ESTIMATED","INTERVENTIONAL",[82],"NA","This study will compare the effects of high-load resistance training to low-load resistance training, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.",[85],"Activity, Motor","2026-01-30",{"date":88,"type":89},"2026-02-02","ACTUAL",{"date":86,"type":89},{"date":92,"type":79},"2027-05-30",{"name":5,"class":6},1]