[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631985":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":35,"locations":46,"responsibleParty":73,"collaborators":25,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":25,"eligibilityCriteria":82,"healthyVolunteers":78,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":25,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":96,"overallStatus":101,"whyStopped":25,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Fayoum University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"EXORA 15","ACTIVE_COMPARATOR","15 mL of bupivacaine 0.25% administered bilaterally",[13],"Procedure: EXORA block 15",{"label":15,"type":10,"description":16,"interventionNames":17},"EXORA 25","25 mL of bupivacaine 0.25% administered bilaterally",[18],"Procedure: EXORA block 25",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","EXORA block 15","15 mL of bupivacaine 0.25% administered bilaterally by ultrasound guided EXORA block",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"EXORA block 25","25 mL of bupivacaine 0.25% administered bilaterally by ultrasound guided EXORA block",[15],[31],{"name":32,"affiliation":33,"role":34},"Mohamed A Hamed,, MD","Faculty of medicine, Fayoum university","PRINCIPAL_INVESTIGATOR",[36,42],{"name":37,"role":38,"phone":39,"phoneExt":40,"email":41},"Mohammed R Gomaa, Bch","CONTACT","1097830069","+20","mr147@fayoum.edu.eg",{"name":43,"role":38,"phone":44,"phoneExt":40,"email":45},"Mohamed H Ragab, MD","1090050298 Ext. +20","mhr02@fayoum.edu.eg",[47],{"facility":48,"status":25,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Fayoum University hospital","El Fayoum Qesm","Faiyum Governorate","63514","Egypt","EG",{"type":55,"coordinates":56},"Point",[57,58],30.83333,29.31667,{"lat":58,"lon":57},[61,65,67,68,71,72],{"name":62,"role":38,"phone":63,"phoneExt":40,"email":64},"Mohamed A Hamed, MD","1010509736","mah07@fayoum.edu.eg",{"name":43,"role":38,"phone":66,"phoneExt":40,"email":45},"1090050298",{"name":62,"role":34,"phone":25,"phoneExt":25,"email":25},{"name":69,"role":70,"phone":25,"phoneExt":25,"email":25},"Omar S Farghaly, MD","SUB_INVESTIGATOR",{"name":43,"role":70,"phone":25,"phoneExt":25,"email":25},{"name":37,"role":70,"phone":25,"phoneExt":25,"email":25},{"type":34,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Mohamed Ahmed Hamed","Professor of Anesthesiology","100631985","low-versus-standard-volume-exora-block-in-laparoscopic-cholecystectomy-100631985",false,"NCT07507799","Low Versus Standard Volume EXORA Block in Laparoscopic Cholecystectomy","Analgesic Efficacy of Low-Volume Versus Standard-Volume 0.25% Bupivacaine for Ultrasound-Guided External Oblique and Rectus Abdominis Plane Block in Laparoscopic Cholecystectomy, A Randomized Non-Inferiority Trial","Inclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) physical status I or II.\n* Scheduled for elective laparoscopic cholecystectomy under general anesthesia.\n\nExclusion Criteria:\n\n* • Patient refusal to participate.\n\n  * Obese patients with a body mass index of more than 35 kg\u002Fm2.\n  * Known cognitive impairment or use of psychiatric drugs\n  * Known allergy to local anesthetics\n  * Infection at the needle insertion site.\n  * Coagulopathy, or bleeding disorders.\n  * Pregnancy\n  * History of chronic pain or chronic opioid use.\n  * Previous major upper abdominal surgery (which alters the fascial planes and anatomy).\n\nCriteria for Withdrawal from Study Analysis (Drop-outs):\n\n* Conversion to open cholecystectomy during surgery.\n* Failed EXORA block","ALL","18 Years","65 Years",{"count":87,"type":88},96,"ESTIMATED","INTERVENTIONAL",[91],"NA","The original EXORA block used high local anesthetic volume (50 mL total), raising concerns about local anesthetic systemic toxicity (LAST). In such a bilaterally administered regional technique, evaluating the efficacy of a reduced-volume approach is warranted to maximize patient safety.",[94,95],"Pain, Postoperative","Post Operative Analgesia",[97,98,99,100],"EXORA","analgesic efficacy","low volume","laparoscopic cholecystectomy","NOT_YET_RECRUITING","2026-04-13",{"date":104,"type":105},"2026-04-16","ACTUAL",{"date":107,"type":88},"2026-04-10",{"date":109,"type":88},"2026-11-02",{"name":5,"class":6},1]