[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555342":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":38,"responsibleParty":196,"collaborators":24,"id":199,"slug":200,"hasResults":201,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":205,"eligibilityCriteria":206,"healthyVolunteers":201,"sex":207,"minAge":208,"maxAge":24,"enrollmentInfo":209,"targetDuration":24,"studyType":212,"phases":213,"briefSummary":215,"conditions":216,"keywords":24,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":221,"startDateStruct":224,"completionDateStruct":226,"leadSponsor":228,"locationsCount":229},{"fullName":5,"class":6},"University Hospital Heidelberg","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention arm","EXPERIMENTAL","Additional insertion of a lumbar drainage.",[13],"Other: External drainage of intraventricular hemorrhage",{"label":15,"type":16,"description":17,"interventionNames":18},"Control arm","ACTIVE_COMPARATOR","Standard of care consists of drainage of CSF via EVD with or without intraventricular thrombolysis.",[13],[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"External drainage of intraventricular hemorrhage","An EVD is required to be eligible for the DRAIN IVH study. Weaning from the EVD is at the discretion of the local investigators. Imaging is at discretion of local investigators. Use, timing and frequency of fibrinolysis via EVD is at local discretion, too.",[15,9],null,[26],{"name":27,"affiliation":28,"role":29},"Silvia Schönenberger, MD","Heidelberg University Hospital, Department of Neurology","PRINCIPAL_INVESTIGATOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":24,"email":34},"CONTACT","0049\u002F6221\u002F567504","silvia.schoenenberger@med.uni-heidelberg.de",{"name":36,"role":32,"phone":33,"phoneExt":24,"email":37},"Min Chen, MD","min.chen@med.uni-heidelberg.de",[39,59,73,86,98,111,124,137,147,157,170,183],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Department of Neurology, University Hospital Heidelberg","RECRUITING","Heidelberg","Baden-Wurttemberg","69120","Germany","DE",{"type":48,"coordinates":49},"Point",[50,51],8.69079,49.40768,{"lat":51,"lon":50},[54,57],{"name":55,"role":32,"phone":56,"phoneExt":24,"email":34},"Silvia Schönenberger, Dr.","0049-6221-5637549",{"name":55,"role":58,"phone":24,"phoneExt":24,"email":24},"SUB_INVESTIGATOR",{"facility":60,"status":41,"city":61,"state":62,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"LMU München","München","Bavaria",{"type":48,"coordinates":64},[65,66],13.46314,48.69668,{"lat":66,"lon":65},[69],{"name":70,"role":32,"phone":71,"phoneExt":24,"email":72},"Konstantinos Dimitriadis, Prof. Dr.","004989440073690","Konstantin.Dimitriadis@med.uni-muenchen.de",{"facility":74,"status":41,"city":75,"state":24,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Augsburg University Hospital","Augsburg",{"type":48,"coordinates":77},[78,79],10.89851,48.37154,{"lat":79,"lon":78},[82],{"name":83,"role":32,"phone":84,"phoneExt":24,"email":85},"Hauke Schneider, PD Dr.","0049\u002F821\u002F400-01","hauke.schneider@uk-augsburg.de",{"facility":87,"status":88,"city":89,"state":24,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"Charite Universitätsmedizin Berlin","NOT_YET_RECRUITING","Berlin",{"type":48,"coordinates":91},[92,93],13.41053,52.52437,{"lat":93,"lon":92},[96],{"name":97,"role":32,"phone":24,"phoneExt":24,"email":24},"Stefan Wolf, Dr.",{"facility":99,"status":41,"city":100,"state":24,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Düsseldorf Universitiy Hospital","Düsseldorf",{"type":48,"coordinates":102},[103,104],6.77927,51.22319,{"lat":104,"lon":103},[107],{"name":108,"role":32,"phone":109,"phoneExt":24,"email":110},"Kerim Beseoglu, Prof. Dr.","+49 (0) 2 11-81 00","Kerim.Beseoglu@med.uni-duesseldorf.de",{"facility":112,"status":88,"city":113,"state":24,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":114,"geoPoint":118,"contacts":119},"Frankfurt University Hospital","Frankfurt",{"type":48,"coordinates":115},[116,117],10.53333,49.68333,{"lat":117,"lon":116},[120],{"name":121,"role":32,"phone":122,"phoneExt":24,"email":123},"Marcus Czabanka, Prof. Dr.","049\u002F69 63010","Czabanka@med.uni-frankfurt.de",{"facility":125,"status":88,"city":126,"state":24,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":127,"geoPoint":131,"contacts":132},"Goettingen University Hospital","Göttingen",{"type":48,"coordinates":128},[129,130],9.93228,51.53443,{"lat":130,"lon":129},[133],{"name":134,"role":32,"phone":135,"phoneExt":24,"email":136},"Tammam Abboud, PD Dr.","049\u002F551\u002F390","Tammam.abboud@med.uni-goettingen.de",{"facility":138,"status":41,"city":42,"state":24,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":139,"geoPoint":141,"contacts":142},"Augsburg University Hospital Department of Neurosurgery",{"type":48,"coordinates":140},[50,51],{"lat":51,"lon":50},[143],{"name":144,"role":32,"phone":145,"phoneExt":24,"email":146},"Nadine Lilla, PD Dr.","0049\u002F821 400-01","Nadine.Lilla@uk-augsburg.de",{"facility":148,"status":41,"city":42,"state":24,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":149,"geoPoint":151,"contacts":152},"Heidelberg University Hospital Department of Neurosurgery",{"type":48,"coordinates":150},[50,51],{"lat":51,"lon":50},[153],{"name":154,"role":32,"phone":155,"phoneExt":24,"email":156},"Martin Jakobs, Prof. Dr.","0049\u002F6221\u002F560","martin.jakobs@med.uni-heidelberg.de",{"facility":158,"status":88,"city":159,"state":24,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":160,"geoPoint":164,"contacts":165},"Mainz University Hospital","Mainz",{"type":48,"coordinates":161},[162,163],8.28008,49.98185,{"lat":163,"lon":162},[166],{"name":167,"role":32,"phone":168,"phoneExt":24,"email":169},"Thomas Kerz, Dr.","+49 6131 39-0","kerz@uni-mainz.de",{"facility":171,"status":41,"city":172,"state":24,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":173,"geoPoint":177,"contacts":178},"Mannheim University Hospital","Mannheim",{"type":48,"coordinates":174},[175,176],8.46694,49.4891,{"lat":176,"lon":175},[179],{"name":180,"role":32,"phone":181,"phoneExt":24,"email":182},"Christopher Beynon, Prof. Dr.","0049\u002F621\u002F383-0","christopher.beynon@umm.de",{"facility":184,"status":41,"city":185,"state":24,"zip":24,"country":45,"countryCode":46,"cosmosGeoPoint":186,"geoPoint":190,"contacts":191},"Osnabrück Clinic","Osnabrück",{"type":48,"coordinates":187},[188,189],8.0498,52.27264,{"lat":189,"lon":188},[192],{"name":193,"role":32,"phone":194,"phoneExt":24,"email":195},"Volker Schulte, Dr.","049\u002F541\u002F4050","Volker.Schulte@klinikum-os.de",{"type":29,"investigatorFullName":197,"investigatorTitle":198,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Dr. Silvia Schönenberger, MD","Prof. Dr. Silvia Schönenberger","100555342","lumbar-drainage-of-intraventricular-hemorrhage-100555342",false,"NCT06510842","Lumbar Drainage of Intraventricular Hemorrhage","Lumbar Drainage of Intraventricular Hemorrhage The DRAIN IVH Randomized Controlled Trial","DRAIN IVH","Inclusion Criteria:\n\n* ICH with IVH (with hemorrhage in the 3rd and\u002For 4rth ventricle) with the need for EVD placement due to acute hydrocephalus\n* Age ≥ 18 y\n* Lumbar drain can be inserted within 72 h after symptom onset or patient last seen well\n\nExclusion Criteria:\n\n* Premorbid mRS score \\> 2\n* Pregnancy\n* Life expectancy \\\u003C6 months\n* Patient\u002Ffamily\u002Fcaregiver unwilling or unlikely to opt for at least two weeks of aggressive therapy prior to consideration of transition to comfort measures\u002Fdiscontinuation of life support measures.\n* Treating physicians deeming the prognosis as so grave that an aggressive therapy is not warranted.\n* Other clear contraindication for treatment with a lumbar drain","ALL","18 Years",{"count":210,"type":211},354,"ESTIMATED","INTERVENTIONAL",[214],"NA","Intracerebral hemorrhage (ICH) is a debilitating and fatal disease, especially when the hemorrhage is also entering the cerebral ventricles leading to acute hydrocephalus. In these cases, patients need a drainage through external ventricular drains (EVD). In the longer term, patients often need a permanent ventriculoperitoneal (VP) shunt to avoid hydrocephalus. Here we hypothesize that the early insertion of a lumbar drainage in addition to the EVD could lead to better functional outcome and avoidance of VP shunting by drainage of the blood which promotes inflammatory and adverse effects in the subarachnoid space. For that we propose a multi-center randomized clinical trial to investigate the hypothesis.",[217,218,219],"Intraventricular Hemorrhage","Lumbar Drainage","External Ventricular Drainage","2026-01-26",{"date":222,"type":223},"2026-01-28","ACTUAL",{"date":225,"type":223},"2025-01-16",{"date":227,"type":211},"2029-07",{"name":5,"class":6},12]