[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553729":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":64,"collaborators":67,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":26,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":26,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Texas A&M University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"LZF Supplement","ACTIVE_COMPARATOR","Participants will take one LZF supplement daily for six months.",[13],"Dietary Supplement: Active Comparator (Lutein, zeaxanthin, and fish oil supplement (LZF)",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Participants will take on placebo supplement daily for six months.",[19],"Dietary Supplement: Placebo Comparator",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Active Comparator (Lutein, zeaxanthin, and fish oil supplement (LZF)","Each participant will be assigned to t a LZF supplement daily for six months",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo Comparator","Each participant will be assigned to take a placebo supplement daily for six months",[15],[32],{"name":33,"affiliation":5,"role":34},"Karen M Beathard, PhD","PRINCIPAL_INVESTIGATOR",[36,40],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","979-220-2281","karen-beathard@tamu.edu",{"name":41,"role":37,"phone":42,"phoneExt":26,"email":43},"Steven E Riechman, PhD","979-862-3213","sriechman@tamu.edu",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Gilchrist Building","RECRUITING","College Station","Texas","77843","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-96.33441,30.62798,{"lat":57,"lon":56},[60,62],{"name":61,"role":37,"phone":42,"phoneExt":26,"email":43},"Steven E. Riechman, PhD",{"name":63,"role":37,"phone":38,"phoneExt":26,"email":39},"Karen M. Beathard, PhD",{"type":34,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Karen Beathard","Instructional Associate Professor",[68],{"name":69,"class":6},"Allen Foundation Inc.","100553729","lutein-zeaxathin-and-fish-oil-supplementation-100553729",false,"NCT06489873","Lutein, Zeaxathin, and Fish Oil Supplementation","The Role of Lutein, Zeaxanthin, and Fish Oil on Cognitive Function and Bone Health in Healthy Adults","Inclusion Criteria:\n\n* \\\u003C.43 MPOD, a self-reported best-corrected vision of 20\u002F40 or better in each eye, a BMI range of 18.5-30, and meets the inclusion criteria on the preliminary participant questionnaire.\n\nExclusion Criteria:\n\n* allergic to lutein, zeaxanthin, or fish oil, taking supplements with \\>6 mg lutein and\u002For \\>2 mg zeaxanthin for more than two months before study starts, MPOD between \\>.43, self-reported condition of vertigo, diabetic retinopathy, retinitis pigmentosa, optic neuropathy, retinal vascular occlusions, strabismus, autoimmune disorders related to visual health, currently pregnant or trying to become pregnant, history of concussion, vegan (due to gelatin in the placebo), and\u002For taking neuroactive medications, such as Ritalin, Adderall, antidepressants, etc.",true,"ALL","18 Years","45 Years",{"count":82,"type":83},80,"ESTIMATED","INTERVENTIONAL",[86],"NA","The goal of this clinical trial is to learn the impact of lutein, zeaxanthin, and fish oil (LZF) supplementation in healthy adults.\n\nThe main question it aims to answer is: Will supplementation with LZF improve macular pigment optical density (MPOD), cognitive performance and bone mass compared to controls after six months?\n\nSubjects with an MPOD \\\u003C.43 will significantly improve MPOD after 6-months of LZF supplementation.\n\nConsuming a LZFO supplement for 6-months will improve visual cognitive performance. Consuming a LZFO supplement for 6-months will improve bone density.\n\nParticipants will be asked to take either a LZF supplement or placebo daily for 6 months.",[89,90,91],"Cognitive Performance","Age-Related Macular Degeneration","Bone Loss",[93,94,95,96,97,98,99,100,89],"Lutein","Zeaxanthin","Fish Oil","Supplement","Macular Pigment","Macular Pigment Optical Density","Cognition","Age-related Macular Degeneration","2025-09-24",{"date":103,"type":104},"2025-09-30","ACTUAL",{"date":106,"type":104},"2024-02-07",{"date":108,"type":83},"2026-05-01",{"name":5,"class":6},1]