[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100190666":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":29,"responsibleParty":47,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Ohio State University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Altered Stiffness",null,"Tissue stiffness will be evaluated in subjects those with disease conditions where stiffness changes from normal. These studies will be repeated for reproducibility.",{"label":13,"type":10,"description":14,"interventionNames":10},"Healthy Volunteers","Tissue stiffness will be evaluated in normal subjects to determine the normal values. These studies will be repeated for reproducibility.",[16],{"name":17,"affiliation":5,"role":18},"Arunark Kolipaka, PhD","PRINCIPAL_INVESTIGATOR",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Arunark Kolipaka","CONTACT","614-366-0268","arunark.kolipaka@osumc.edu",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Kristin L Thompson, B.S.","614-366-5429","Kristin.Thompson@osumc.edu",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"The Ohio State University Wexner Medical Center","RECRUITING","Columbus","Ohio","43210","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-82.99879,39.96118,{"lat":42,"lon":41},[45,46],{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},{"name":17,"role":18,"phone":10,"phoneExt":10,"email":10},{"type":48,"investigatorFullName":21,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Associate Professor","100190666","magnetic-resonance-elastography-as-a-method-to-estimate-stiffness-of-soft-tissues-100190666",false,"NCT01757730","Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues","MRE","Inclusion Criteria:\n\nAny participant 18 years or older and are MR safe.\n\nExclusion Criteria:\n\nThat study participants will be excluded if they have any unapproved metal in their bodies, or if the volunteers are pregnant or possible of becoming pregnant. Also if the participants are claustrophobic.",true,"ALL","18 Years",{"count":61,"type":62},1000,"ESTIMATED","OBSERVATIONAL","Magnetic resonance elastography is a novel non-invasive MRI technique to obtain stiffness of soft tissues such as liver, heart, kidneys, etc. In this imaging technique a person is laid in an MR scanner and a paddle (plastic drum) is put on the area of interest to send sound vibration via a speaker placed outside the scan room which is connecting plastic drum via a plastic tube. These vibrations are scanned using MRI to estimate the stiffness of soft tissues such as liver, heart, kidneys, breast etc.",[66,67,68,69],"Heart Failure","Liver Fibrosis","Cardiac Transplant Rejection","Aortic Aneurysms","2025-04-04",{"date":72,"type":73},"2025-04-06","ACTUAL",{"date":75,"type":10},"2012-03",{"date":77,"type":62},"2028-03-01",{"name":21,"class":6},1]