[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100238835":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":30,"centralContacts":35,"locations":41,"responsibleParty":59,"collaborators":10,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":10,"enrollmentInfo":72,"targetDuration":10,"studyType":75,"phases":10,"briefSummary":76,"conditions":77,"keywords":10,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Ohio State University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Normal Volunteers",null,"60 normal volunteers will be recruited. Each volunteer will undergo a single MRE scan (with Resoundant driver System ) of their abdominal aorta.",[13],"Device: Resoundant Driver System",{"label":15,"type":10,"description":16,"interventionNames":17},"Patients with AAA","Fifty to sixty five patients with AAA will be recruited. These patients will undergo MRE (with Resoundant driver system) of their AAA every six months for three years, or until the study ends or until the time of surgical repair or death due to rupture of AAA or other causes.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Open Surgical Repair Patients","Fifty to sixty five patients patients undergoing open surgical repair will be recruited and undergo MRE (with Resoundant driver system) prior to surgery",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DEVICE","Resoundant Driver System","This device is used to generate vibrations at the area of interest. The device has an active driver, a loud speaker sitting outside the scanner area, and a passive driver, which is shaped like a silicone paddle, which is secured with velcro straps to the area being imaged. Sound waves from the active driver travel through a tube attached to the passive driver and generate vibrations, images of which are captured by the MR scanner.",[9,19,15],[29],"Driver",[31],{"name":32,"affiliation":33,"role":34},"Arunark Kolipaka, PhD","The Ohio State University Medical Center Dept. of Radiology","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":10,"email":40},"Kristin L Thompson, B.S.","CONTACT","614-366-5429","Kristin.Thompson@osumc.edu",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"The Ohio State University Medical Center","RECRUITING","Columbus","Ohio","43210","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-82.99879,39.96118,{"lat":54,"lon":53},[57,58],{"name":37,"role":38,"phone":39,"phoneExt":10,"email":40},{"name":32,"role":34,"phone":10,"phoneExt":10,"email":10},{"type":34,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Arunark Kolipaka","Associate Professor","100238835","magnetic-resonance-elastography-in-patients-with-abdominal-aortic-aneurysms-100238835",false,"NCT02387255","Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms","AAA-MRE","Inclusion Criteria:\n\n* Must be able to lie flat on their back in the scanner for up to 60 minutes\n* Must be able to hold breath for up to 15 seconds\n\nExclusion Criteria:\n\n* Patients who are claustrophobic\n* Patients who are pregnant\n* Patients with any unapproved, non-MRI save metal\u002Fdevices in or on their body",true,"ALL","20 Years",{"count":73,"type":74},165,"ESTIMATED","OBSERVATIONAL","The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA). For patients with AAA, MRE is a more sensitive and superior method of determining the risk for rupture of AAA based on stiffness estimates when compared to the current, crude method of assessing risk based on measurement of the diameter of the aneurysm. The investigators will also validate the stiffness estimates against gold standard i.e. mechanical testing and histopathology only AAA patients undergoing AAA surgery.",[78],"Abdominal Aortic Aneurysm","2025-04-04",{"date":81,"type":82},"2025-04-08","ACTUAL",{"date":84,"type":10},"2014-10",{"date":86,"type":74},"2028-10-31",{"name":5,"class":6},1]