[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626463":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":40,"locations":50,"responsibleParty":70,"collaborators":31,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":31,"eligibilityCriteria":79,"healthyVolunteers":75,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":31,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":98,"whyStopped":31,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Fatih Sultan Mehmet Training and Research Hospital","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1 (Magnetotherapy Group):","ACTIVE_COMPARATOR","Participants will receive pulsed magnetotherapy five days per week for a total of 15 sessions. Treatment parameters will be 50 Hz frequency, 2-3 mT magnetic field intensity, and 15-20 minutes per session. In addition, participants in this group will use a standard nighttime wrist splint and follow a standardized home exercise program consisting of nerve and tendon gliding exercises.",[13],"Device: Arm 1: Active Magnetotherapy Group",{"label":15,"type":16,"description":17,"interventionNames":18},"Group 2 (Placebo Magnetotherapy Group)","SHAM_COMPARATOR","Participants will receive treatment using the same device, with identical appearance and session duration; however, the device will not generate a magnetic field (sham mode). Participants in this group will also use a standard nighttime wrist splint and follow the same standardized home exercise program (nerve and tendon gliding exercises).",[19],"Device: Arm 2: Sham (Placebo) Magnetotherapy Group",{"label":21,"type":6,"description":22,"interventionNames":23},"Group 3 (Routine\u002FConservative Treatment Group)","Participants in this group will use a standard nighttime wrist splint and follow the standardized home exercise program (nerve and tendon gliding exercises). These participants will be placed on a wait-list for magnetotherapy.",[24],"Other: Arm 3: Conservative Treatment (Wait-List Control) Group",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DEVICE","Arm 1: Active Magnetotherapy Group","Participants assigned to this group will receive active pulsed electromagnetic field (PEMF) therapy administered five days per week for three consecutive weeks, totaling 15 treatment sessions. Each session will last 15-20 minutes. The treatment will be delivered using a clinically approved medical device set at a frequency of 50 Hz and a magnetic field intensity of 2-3 millitesla (mT). The application will be performed in a controlled clinical setting by trained healthcare personnel.\n\nIn addition to magnetotherapy, all participants in this group will receive standard conservative treatment, including the use of a neutral-position wrist splint during nighttime and a standardized home-based exercise program consisting of nerve gliding and tendon gliding exercises. Participants will be instructed on proper exercise performance and adherence will be monitored throughout the study period.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Arm 2: Sham (Placebo) Magnetotherapy Group","Participants in this group will undergo a sham magnetotherapy procedure using the same device, with identical appearance, positioning, session duration, and application protocol as the active treatment group. However, the device will be set to a mode that does not generate a magnetic field. This approach is designed to maintain participant blinding and control for placebo effects.\n\nSimilar to the active group, participants will receive standard conservative treatment consisting of nighttime wrist splint use and the same standardized nerve and tendon gliding home exercise program. Exercise instructions and compliance monitoring will be identical to those of the active treatment group.",[15],{"type":6,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Arm 3: Conservative Treatment (Wait-List Control) Group","Participants in this group will receive standard conservative management only, including nighttime wrist splinting and the standardized home-based nerve and tendon gliding exercise program. No magnetotherapy device will be applied during the study period.\n\nTo ensure ethical considerations, participants in this group will be placed on a wait-list and may be offered magnetotherapy after completion of the follow-up assessments. Compliance with splint use and exercise performance will be monitored similarly to the other groups.",[21],[41,46],{"name":42,"role":43,"phone":44,"phoneExt":31,"email":45},"Orçun Ünalan, medical doctor","CONTACT","+905337335856","orcununalan@gmail.com",{"name":47,"role":43,"phone":48,"phoneExt":31,"email":49},"Pınar Akpınar, medical doctor","+905057877442","pinar.pinarakpinar@gmail.com",[51],{"facility":52,"status":31,"city":53,"state":53,"zip":54,"country":55,"countryCode":31,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Fatih Sultan Mehmet Research and Training Hospital","Istanbul","34734","Turkey (Türkiye)",{"type":57,"coordinates":58},"Point",[59,60],28.94966,41.01384,{"lat":60,"lon":59},[63,64,67],{"name":42,"role":43,"phone":44,"phoneExt":31,"email":45},{"name":65,"role":66,"phone":31,"phoneExt":31,"email":31},"Orçun Ünalan, MD","PRINCIPAL_INVESTIGATOR",{"name":68,"role":69,"phone":31,"phoneExt":31,"email":31},"Pınar Akpınar, MD","SUB_INVESTIGATOR",{"type":66,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Orçun Ünalan","medical doctor","100626463","magnetotherapy-in-carpal-tunnel-syndrome-randomized-controlled-study-100626463",false,"NCT07435961","Magnetotherapy in Carpal Tunnel Syndrome: Randomized Controlled Study","Evaluation of the Effectiveness of Magnetotherapy in Patients With Carpal Tunnel Syndrome: A Placebo-Controlled, Triple-Arm, Randomized, Double-Blind Study","Inclusion Criteria:\n\n* Adults aged between 18 and 65 years.\n\nClinical diagnosis of carpal tunnel syndrome (CTS) based on physical examination findings, including positive Tinel and\u002For Phalen tests and hypoesthesia in the 3rd to 5th digits.\n\nElectrophysiologically confirmed mild-to-moderate carpal tunnel syndrome based on electromyography (EMG) findings.\n\nExclusion Criteria:\n\n* Severe carpal tunnel syndrome confirmed electrophysiologically by electromyography (EMG).\n\nHistory of previous surgical intervention for carpal tunnel syndrome.\n\nPresence of other peripheral nerve entrapments (e.g., ulnar nerve entrapment, radial nerve entrapment).\n\nElectrophysiologically confirmed polyneuropathy or cervical radiculopathy\u002Fcervical discopathy.\n\nRheumatologic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus).\n\nDiabetes mellitus (Type 1 or Type 2).\n\nPregnancy.\n\nPresence of electronic implants such as cardiac pacemaker, cochlear implant, or implantable defibrillator.\n\nActive acute infection.\n\nHistory of malignancy.\n\nReceipt of physical therapy or rehabilitation for the wrist or surrounding area within the past 6 months.\n\nCorticosteroid injection to the wrist within the past 6 months.\n\nHyperthyroidism or adrenal gland hyperfunction.\n\nOpen growth plates (epiphyseal plates not closed).\n\nParoxysmal neurological disorders (e.g., epilepsy).\n\nMyasthenia gravis.\n\nRegular use of pain medications such as pregabalin, duloxetine, or non-steroidal anti-inflammatory drugs (NSAIDs).","ALL","18 Years","65 Years",{"count":84,"type":85},60,"ESTIMATED","INTERVENTIONAL",[88],"NA","This study is designed to investigate the effectiveness of low-frequency pulsed electromagnetic field therapy in individuals diagnosed with mild-to-moderate carpal tunnel syndrome (CTS). This double-blind, randomized controlled trial will randomly assign participants into three groups:\n\nGroup 1: Active magnetotherapy\n\nGroup 2: Placebo magnetotherapy (treatment using an identical device that does not generate a magnetic field)\n\nGroup 3: Routine (conservative) treatment group\n\nAll participants will receive a standard nighttime wrist splint and a standardized nerve and tendon gliding exercise protocol. Magnetic field applications will be administered five days per week for a total of 15 sessions. Assessments will be conducted at baseline (T0), at the end of treatment (T1 - Week 3), at 1 month (T2), and at 3 months (T3).\n\nThe primary outcome measures include the Boston Carpal Tunnel Questionnaire (BCTQ), pain intensity assessed by the Visual Analog Scale (VAS), functional status measured by QuickDASH, median nerve cross-sectional area assessed by ultrasonography, sensory function evaluated using the Semmes-Weinstein monofilament test, grip strength measured by dynamometry, and clinical test results (Tinel and Phalen tests). Secondary outcomes include sleep quality assessed by the Pittsburgh Sleep Quality Index (PSQI) and patient satisfaction.\n\nThis study aims to contribute to the scientific evidence regarding the effectiveness of magnetotherapy as a non-invasive treatment option for carpal tunnel syndrome.",[91,92,93],"Magnetotherapy","Carpal Tunnel Syndrome (CTS)","Median Nerve Compression",[95,96,97],"median nerve compression","carpal tunnel syndrome(cts)","magnetotherapy","NOT_YET_RECRUITING","2026-02-21",{"date":101,"type":102},"2026-02-27","ACTUAL",{"date":104,"type":85},"2026-02-01",{"date":106,"type":85},"2026-11-01",{"name":5,"class":6},1]