[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591733":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":10,"centralContacts":30,"locations":39,"responsibleParty":56,"collaborators":58,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":10,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":10,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Region Västerbotten","OTHER_GOV",[8,14,17,21],{"label":9,"type":10,"description":11,"interventionNames":12},"LS Urology",null,"Male patients (≥18 years), undergoing circumcision due to phimosis at the Department of Urology. Diagnosis of lichen sclerosus (LS) confirmed by histopathological examination of the foreskin. Participants will complete questionnaires and provide biological samples (e.g., skin, urine, and fecal samples) for exploratory analyses. Follow-up will be conducted to assess long-term treatment outcomes.",[13],"Procedure: Circumcision",{"label":15,"type":10,"description":16,"interventionNames":10},"LS dermatology","Male patients (≥18 years), diagnosed with LS in outpatient care at the Department of Dermatology. Participants will complete questionnaires and be followed over time to evaluate treatment and quality of life.",{"label":18,"type":10,"description":19,"interventionNames":20},"Controls - Urology","Male patients (≥18 years), undergoing circumcision at the Department of Urology, with no histopathological evidence of LS. These participants will provide biological samples at baseline and serve as urology-based controls for comparison with LS patients.",[13],{"label":22,"type":10,"description":23,"interventionNames":10},"Controls - General Population","Male participants (≥18 years) without any known genital symptoms or history of LS, recruited from the general population. They will complete the same questionnaire as other study groups but will not be sampled or followed longitudinally.",[25],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"PROCEDURE","Circumcision","Circumcision performed as part of standard clinical care in patients with phimosis, which may be caused by lichen sclerosus. The procedure is not assigned by the study but observed as part of routine treatment",[18,9],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Maja af Klinteberg, MD, PhD","CONTACT","0046-90785 00 00","maja.af.klinteberg@umu.se",{"name":37,"role":33,"phone":10,"phoneExt":10,"email":38},"Amir Sherif, MD, PhD","amir.sherif@umu.se",[40],{"facility":41,"status":42,"city":43,"state":10,"zip":10,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Umeå University Hospital","RECRUITING","Umeå","Sweden","SE",{"type":47,"coordinates":48},"Point",[49,50],20.25972,63.82842,{"lat":50,"lon":49},[53],{"name":54,"role":33,"phone":55,"phoneExt":10,"email":35},"Maja af Klinteberg","0046-7850000",{"type":57,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[59],{"name":60,"class":61},"Umeå University","OTHER","100591733","male-lichen-sclerosus---risk-factors-treatment-and-impact-on-quality-of-life-100591733",false,"NCT06984263","Male Lichen Sclerosus - Risk Factors, Treatment, and Impact on Quality of Life","Inclusion Criteria for patients with LS (LS Urology and LS dermatology):\n\n* Biologically male\n* ≥18 years old\n* Referred to the dermatology department or the urology department in Västerbotten and diagnosed with LS.\n* Must be able to read and write Swedish to fill in questionnaire and informed consent.\n\nInclusion criteria for control group \"Controls - Urology\":\n\n* Biologically male\n* ≥18 years old\n* Phimosis without LS, treated with circumcision at the urology department in Västerbotten\n* Must be able to read and write Swedish to fill in questionnaire and informed consent.\n\nInclusion criteria for control group \"Controls - General Population\":\n\n* Biologically male with male genitalia\n* ≥18 years old\n* No genital symptoms\n* Must be able to read and write Swedish to fill in questionnaire and informed consent.\n\nExclusion Criteria for all groups:\n\n* Age under 18 years old\n* Not able to read and write in Swedish.\n* Unable to leave an informed consent to participate.",true,"MALE","18 Years",{"count":72,"type":73},300,"ESTIMATED","OBSERVATIONAL","This observational study aims to evaluate routine treatment outcomes in men with lichen sclerosus (LS), including a long-term follow-up to assess disease progression and histopathological changes. The study also investigates potential risk factors for LS and the disease's impact on quality of life and sexual health.",[77],"Lichen Sclerosus",[79],"lichen sclerosus","2026-02-09",{"date":82,"type":83},"2026-02-10","ACTUAL",{"date":85,"type":83},"2025-10-06",{"date":87,"type":73},"2038-10",{"name":5,"class":6},1]