[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560408":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":33,"locations":42,"responsibleParty":188,"collaborators":192,"id":194,"slug":195,"hasResults":196,"nctId":197,"briefTitle":198,"officialTitle":199,"acronym":200,"eligibilityCriteria":201,"healthyVolunteers":196,"sex":202,"minAge":203,"maxAge":32,"enrollmentInfo":204,"targetDuration":32,"studyType":207,"phases":208,"briefSummary":210,"conditions":211,"keywords":213,"overallStatus":45,"whyStopped":32,"lastUpdateSubmitDate":217,"lastUpdatePostDateStruct":218,"startDateStruct":221,"completionDateStruct":223,"leadSponsor":225,"locationsCount":226},{"fullName":5,"class":6},"University Hospital, Akershus","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Home care","EXPERIMENTAL","Follow-up and management of HF medications at home visits after 1, 2, 3 and 6 weeks performed by telecommunication led by HF nurses in close communication with physician at the institution. Around week 2 a single visit to the primary care physician's office is required.",[13],"Other: Digital follow-up and uptitration of medications at home after hospital discharge for heart failure",{"label":15,"type":16,"description":17,"interventionNames":18},"Hospital care","ACTIVE_COMPARATOR","Follow-up and management of HF medications provided by specialists at the participating institutions' outpatient clinics after 1, 2, 3 and 6 weeks. (Same as the high-intensity arm in STRONG-HF)",[19],"Other: Follow-up and uptitration of medications at the hospital outpatient-clinic after hospital discharge for heart failure",[21,29],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Digital follow-up and uptitration of medications at home after hospital discharge for heart failure","Both arms will treat the patients according to the STRONG-HF intensive care strategy, as recommended by current guidelines. That is up-titration to at least half of maximum tolerated doses of HF medications at discharge, followed by up-titration to maximum tolerated doses after 2 weeks. Safety visits will be performed after 1, 3 and 6 weeks.",[9],[26,27,28],"Dignio (digital healthcare platform)","Checkware (digital healthcare platform)","Nimble (digital healthcare platform)",{"type":6,"name":30,"description":23,"armGroupLabels":31,"otherNames":32},"Follow-up and uptitration of medications at the hospital outpatient-clinic after hospital discharge for heart failure",[15],null,[34,39],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Peder L Myhre, MD, PhD","CONTACT","+47 93025644","p.l.myhre@medisin.uio.no",{"name":40,"role":36,"phone":32,"phoneExt":32,"email":41},"Henrik Schirmer, MD, PhD","henrik.schirmer@medisin.uio.no",[43,56,72,85,98,111,124,137,150,163,176],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":32,"geoPoint":32,"contacts":51},"Akershus University Hospital","RECRUITING","Lørenskog","Akershus","1478","Norway","NO",[52],{"name":53,"role":36,"phone":54,"phoneExt":32,"email":55},"Terjei Øvrebotten, MD","+4767960000","tarjei.ovrebotten@gmail.com",{"facility":57,"status":45,"city":58,"state":59,"zip":60,"country":49,"countryCode":50,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"Drammen Hospital, Vestre Viken HF","Drammen","Vestre Viken","1878",{"type":62,"coordinates":63},"Point",[64,65],10.20449,59.74389,{"lat":65,"lon":64},[68],{"name":69,"role":36,"phone":70,"phoneExt":32,"email":71},"John Munkhaugen, MD PhD","+47 32 80 30 00","johmun@vestreviken.no",{"facility":73,"status":45,"city":74,"state":32,"zip":32,"country":49,"countryCode":50,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Sørlandet Sykehus","Arendal",{"type":62,"coordinates":76},[77,78],8.77253,58.46151,{"lat":78,"lon":77},[81],{"name":82,"role":36,"phone":83,"phoneExt":32,"email":84},"Jarle Jortveit, MD PhD","+4738073000","jarle.jortveit@gmail.com",{"facility":86,"status":45,"city":87,"state":32,"zip":32,"country":49,"countryCode":50,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"Ålesund Hospital","Ålesund",{"type":62,"coordinates":89},[90,91],6.15492,62.47225,{"lat":91,"lon":90},[94],{"name":95,"role":36,"phone":96,"phoneExt":32,"email":97},"Eva Rice, MD","+4770105050","Eva.Rice@helse-mr.no",{"facility":99,"status":45,"city":100,"state":32,"zip":32,"country":49,"countryCode":50,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Innlandet sykehus","Hamar",{"type":62,"coordinates":102},[103,104],11.06798,60.7945,{"lat":104,"lon":103},[107],{"name":108,"role":36,"phone":109,"phoneExt":32,"email":110},"Stine Holmen, MD PhD","+4762333000","b19808@ous-hf.no",{"facility":112,"status":45,"city":113,"state":32,"zip":32,"country":49,"countryCode":50,"cosmosGeoPoint":114,"geoPoint":118,"contacts":119},"Levanger Sykehus","Levanger",{"type":62,"coordinates":115},[116,117],11.29963,63.74644,{"lat":117,"lon":116},[120],{"name":121,"role":36,"phone":122,"phoneExt":32,"email":123},"Matthias Lippert, MD PhD","+4774098000","matthias.lippert@helse-nordtrondelag.no",{"facility":125,"status":45,"city":126,"state":32,"zip":32,"country":49,"countryCode":50,"cosmosGeoPoint":127,"geoPoint":131,"contacts":132},"Østfold Hospital","Moss",{"type":62,"coordinates":128},[129,130],10.65771,59.43403,{"lat":130,"lon":129},[133],{"name":134,"role":36,"phone":135,"phoneExt":32,"email":136},"Kristin Kvakkestad, MD PhD","+4769860000","kristinturcuta@gmail.com",{"facility":138,"status":45,"city":139,"state":32,"zip":32,"country":49,"countryCode":50,"cosmosGeoPoint":140,"geoPoint":144,"contacts":145},"Oslo University Hospital","Oslo",{"type":62,"coordinates":141},[142,143],10.74609,59.91273,{"lat":143,"lon":142},[146],{"name":147,"role":36,"phone":148,"phoneExt":32,"email":149},"Elisabeth Lie, MD PhD","+4723700000","ellie2@ous-hf.no",{"facility":151,"status":45,"city":152,"state":32,"zip":32,"country":49,"countryCode":50,"cosmosGeoPoint":153,"geoPoint":157,"contacts":158},"Stavanger University Hospital","Stavanger",{"type":62,"coordinates":154},[155,156],5.73332,58.97005,{"lat":156,"lon":155},[159],{"name":160,"role":36,"phone":161,"phoneExt":32,"email":162},"Stein Ørn, MD PhD","+4751518080","drsteinorn@hotmail.com",{"facility":164,"status":45,"city":165,"state":32,"zip":32,"country":49,"countryCode":50,"cosmosGeoPoint":166,"geoPoint":170,"contacts":171},"Tromsø University Hospital","Tromsø",{"type":62,"coordinates":167},[168,169],18.95508,69.6489,{"lat":169,"lon":168},[172],{"name":173,"role":36,"phone":174,"phoneExt":32,"email":175},"Kristina Larsby, MD PhD","+4748075247","kristina.elisabet.larsby@unn.no",{"facility":177,"status":45,"city":178,"state":32,"zip":32,"country":49,"countryCode":50,"cosmosGeoPoint":179,"geoPoint":183,"contacts":184},"Tønsberg Sykehus","Tønsberg",{"type":62,"coordinates":180},[181,182],10.40762,59.26754,{"lat":182,"lon":181},[185],{"name":186,"role":36,"phone":187,"phoneExt":32,"email":32},"Erlend Aune, MD PhD","+433342000",{"type":189,"investigatorFullName":190,"investigatorTitle":191,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"PRINCIPAL_INVESTIGATOR","Peder L. Myhre, MD, PhD","Professor",[193],{"name":138,"class":6},"100560408","management-of-patients-with-heart-failure-at-home-after-hospital-discharge-100560408",false,"NCT06576752","Management of Patients With Heart Failure at Home After Hospital Discharge","Contemporary Post-Discharge Management in Heart Failure at Home","STRONG@HOME","Inclusion Criteria:\n\n* Hospital admission within the 72 hours prior to screening for acute HF.\n* NT-proBNP ≥ 1,000 pg\u002FmL measured during the hospitalization\n* Systolic blood pressure ≥ 100 mmHg and of heart rate ≥ 60 bpm within 24 hours before randomization\n* Serum potassium ≤ 5.0 mEq\u002FL (mmol\u002FL).\n* ≤ ½ the optimal dose of ACEi\u002FARB\u002FARNi or beta-blocker or MRA.\n* Written informed consent to participate in the study.\n\nExclusion Criteria:\n\n1. Age below 18 or above 85 years.\n2. Clearly documented intolerance to high doses of beta-blockers\n3. Clearly documented intolerance to high doses of renin-angiotensin system (RAS) blockers (both ACEi and ARB).\n4. Renal disease or estimated glomerular filtration rate (eGFR) below 30 mL\u002Fmin\u002F1.73m2 at screening or history of dialysis.\n5. Prior (defined as less than 30 days from screening) or current enrollment in a HF intervention or participation in an investigational drug or device study within the 30 days prior to screening\n6. Index event (admission for acute HF) triggered primarily by a completely reversable etiology so that it is unlikely the patient will be classified with chronic HF after discharge, such as Takotsubo syndrome (stress cardiomyopathy). In the setting of acute coronary syndrome or tachycardia, this should be managed before considering the presence of HF. This does not apply to patients with chronic HF prior to the index event.\n7. Severe non-adherence to medications\n8. Psychiatric or neurological disorder, cirrhosis, or active malignancy leading to a life expectancy less than 6 months.\n9. History of heart transplant or on a transplant list, or using or planned to be implanted with a ventricular assist device.\n10. Uncorrected thyroid disease, active myocarditis, or known amyloid or hypertrophic obstructive cardiomyopathy.\n11. Inability to comply with all study requirements, due to major co-morbidities, social or financial issues, or a history of noncompliance with medical regimens, that might compromise the patients ability to understand and\u002For comply with the protocol instructions or follow-up procedures.\n12. Low digital competency classified as inability to handle a smartphone or tablet.\n13. Language barriers requiring the need for an external interpreter.\n14. Pregnant or nursing (lactating) women.","ALL","18 Years",{"count":205,"type":206},450,"ESTIMATED","INTERVENTIONAL",[209],"NA","This study aims to assess whether patients with acute heart failure (HF) can achieve the same level of HF-therapies by digital follow-up at home as compared to hospital visits according to the STRONG-HF strategy. Patients admitted to hospital with acute HF will be enrolled and randomized to either follow-up at the hospital out-patient clinic or digital follow-up at home.",[212],"Heart Failure",[214,215,216],"heart failure","digital health","remote monitoring","2026-06-16",{"date":219,"type":220},"2026-06-17","ACTUAL",{"date":222,"type":220},"2024-10-01",{"date":224,"type":206},"2029-12-31",{"name":5,"class":6},11]