[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100390733":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":55,"collaborators":38,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":38,"enrollmentInfo":69,"targetDuration":38,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":81,"overallStatus":43,"whyStopped":38,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Centro Specialistico Odontoiatrico, Rome","NETWORK",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Immediate Implant Placement","ACTIVE_COMPARATOR","prosthetically driven immediate implant placement (TLC implant, Straumann) with bone substitute (BioOss Collagen, Geistlich) filling the gap between the buccal socket wall and the implant surface and a collagen matrix (Fibrogide, Geistlich) positioning at the vestibular aspect to increase soft tissue volume, with immediate (non occlusal loading) prosthetic provisionalization.",[13],"Procedure: Prosthetically driven implant placement",{"label":15,"type":10,"description":16,"interventionNames":17},"Alveolar Ridge Preservation (ARP) + Delayed Implant Placement:","ARP performed with bone substitute (BioOss Collagen, Geistlich) and a collagen matrix placed to seal the socket entrance (Mucograft Seal, Geistlich). After 4 months of healing a prosthetically driven implant (TLC implant, Straumann) will be placed with adjunctive GBR procedure with bone substitute (BioOss Collagen, Geistlich) and a collagen membrane (BioGide, Geistlich) if buccal bone will be \\\u003C 2 mm and soft tissue augmentation with a collagen matrix (Fibrogide, Geistlich) if soft tissue thickness will be \\\u003C 2mm",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Spontaneous Healing + Delayed Implant Placement","extraction socket will be left to heal spontaneously. After 4 months of healing a prosthetically driven implant (TLC implant, Straumann) will be placed with adjunctive GBR procedure with bone substitute (BioOss Collagen, Geistlich) and a collagen membrane (BioGide, Geistlich) if buccal bone will be \\\u003C 2 mm, and soft tissue augmentation with a collagen matrix (Fibrogide, Geistlich) if soft tissue thickness will be \\\u003C 2mm .",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"PROCEDURE","Prosthetically driven implant placement","Insertion of an osseointegrated implant into the bone of anterior maxilla\u002Fmandible, following the right prosthetic plan",[15,9,19],[29],"Prosthetically driven implant installation",[31],{"name":32,"affiliation":5,"role":33},"Marco Clementini, DDS, PhD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":38,"email":39},"CONTACT","00393388378866",null,"mclementini@me.com",[41],{"facility":42,"status":43,"city":44,"state":38,"zip":38,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Centro Specialistico Odontoiatrico (CSO)","RECRUITING","Roma","Italy","IT",{"type":48,"coordinates":49},"Point",[50,51],11.10642,44.99364,{"lat":51,"lon":50},[54],{"name":32,"role":36,"phone":38,"phoneExt":38,"email":39},{"type":33,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":38,"oldOrganization":38},"Marco Clementini","Research Fellow","100390733","management-of-the-fresh-extraction-socket-in-the-aesthetic-area-100390733",false,"NCT04367766","Management of the Fresh Extraction Socket in the Aesthetic Area","Management of the Fresh Extraction Socket in the Aesthetic Area: Alveolar Ridge Preservation vs Immediate Implant Placement vs Delayed Implant Placement","IIP\u002FARP\u002FSH","Inclusion Criteria:\n\n* single tooth extraction in the anterior region of the dentition (including premolars) to be extracted\n* smoking no more than 10 cigarettes\u002Fday,\n* periodontal health (BoP \\\u003C 10%) and good plaque control (\\\u003C 20%)\n* absence of symptomatic periapical radiolucencies, acute abscesses at the site of extraction,\n* extraction sites with less than 30% loss of one or more walls\n* adequate quantity and quality of native bone to achieve primary stability\n\nExclusion Criteria:\n\n* growing patients\n* patients with autoimmune disease, uncontrolled diabetes or immunocompromised\n* history of head and neck radiation for cancer treatment,\n* pregnancy",true,"ALL","18 Years",{"count":70,"type":71},60,"ESTIMATED","INTERVENTIONAL",[74],"NA","After atraumatic tooth extraction and the assessment of the feasibility of immediate implant placement, patients will be randomly assigned to one of three treatment concepts:\n\n1. Immediate Implant Placement and Immediate Provisionalization\n2. Alveolar Ridge Preservation. After 4 months of healing an implant will be placed with simultaneous GBR and\u002For Soft Tissue Augmentation procedures, if needed.\n3. Spontaneous Healing of the socket. After 4 months of healing, an implant will be placedwith simultaneous GBR and\u002For Soft Tissue Augmentation procedures, if needed.\n\nIn all groups, four months after implant placement, a prosthesis will be delivered. From this experimental period onward, patients will be scheduled for maintenance. Clinical, radiographic and volumetric assessment will be performed by clinicians not involved in the surgery and blind with respect to treatment assignment at 1, 3 and 5 years post loading.",[77,78,79,80],"Tooth Extraction Status Nos","Dental Implant","Bone Augmentation","Soft Tissue Augmentation",[82,83,84,85,86,87,88],"Immediate implant placement","alveolar ridge preservation","delayed implant placement","PROMs","implant health","volumetric analysis","tissue augmentation","2023-12-06",{"date":91,"type":92},"2023-12-12","ACTUAL",{"date":94,"type":92},"2023-09-27",{"date":96,"type":71},"2026-08",{"name":5,"class":6},1]