[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629421":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":30,"locations":30,"responsibleParty":39,"collaborators":30,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":30,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":30,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":71,"whyStopped":30,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":30},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Biological drilling at 50 rpm","EXPERIMENTAL","Participants in this group will undergo dental implant site preparation using a very low-speed \"biological\" drilling protocol set at 50 rpm. This arm tests the effect of maximal biologic preservation on peri-implant bone maintenance and stability.",[13],"Procedure: biological drilling at 50 RPM",{"label":15,"type":10,"description":16,"interventionNames":17},"Biological drilling at 150 rpm","Participants in this group will undergo dental implant site preparation using an intermediate low-speed protocol set at 150 rpm. This arm represents a balance between cutting efficiency and reduced thermal risk",[18],"Procedure: biological drilling at 150 RPM",{"label":20,"type":10,"description":21,"interventionNames":22},"Biological drilling at 300 rpm","Participants in this group will undergo dental implant site preparation using a higher low-speed protocol set at 300 rpm. This arm tests whether increasing speed within the \"biological\" range affects marginal bone remodeling",[23],"Procedure: biological drilling at 300 RPM",[25,31,35],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","biological drilling at 50 RPM","Biological drilling (no irrigation) at 50 rpm for all sequential drills.",[9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"biological drilling at 150 RPM","Biological drilling (no irrigation) at 150 rpm for all sequential drills.",[15],{"type":26,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"biological drilling at 300 RPM","Biological drilling (no irrigation) at 300 rpm for all sequential drills.",[20],{"type":40,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Omar Emam","Dr.","100629421","mandibular-biological-drilling-at-different-speeds-for-dental-implant-placement-100629421",false,"NCT07474454","Mandibular Biological Drilling at Different Speeds for Dental Implant Placement","Radiographic Assessment of Mandibular Biological Drilling at Different Drilling Speeds: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Adult patients aged 20-60 years.\n* Partially edentulous patients requiring a single dental implant in the mandible.\n* Adequate bone height and width at the implant site to accommodate the planned implant dimensions without the need for advanced grafting.\n* Good oral hygiene (full-mouth plaque and bleeding scores within acceptable limits).\n* Patients willing to participate, available for 12-month follow-up, and able to sign informed consent.\n\nExclusion Criteria:\n\n* Systemic diseases or conditions that may compromise bone healing (e.g. uncontrolled diabetes, immunosuppression, recent radiotherapy in head and neck region).\n* Smoking more than 10 cigarettes\u002Fday or heavy vaping.\n* Pregnant or lactating women.\n* History of bisphosphonate or other anti-resorptive therapy affecting bone metabolism.\n* Active periodontal disease or poor oral hygiene.\n* Acute infection or pathology at the planned implant site.\n* Need for simultaneous major bone grafting at the same site.\n* Bruxism or severe parafunctional habits.","ALL","20 Years","60 Years",{"count":54,"type":55},39,"ESTIMATED","INTERVENTIONAL",[58],"NA","This randomized controlled clinical trial aims to evaluate the effect of different biological drilling speeds (50, 150, and 300 rpm) during implant osteotomy preparation in the mandible on marginal bone level changes and implant stability. Thirty-nine patients requiring a single dental implant in the mandible will be randomly allocated into three groups according to drilling speed. All implants will be placed using a biological drilling protocol without irrigation. Implant stability will be measured using resonance frequency analysis at implant placement and follow-up visits. Marginal bone levels will be evaluated radiographically using standardized periapical radiographs during the follow-up period up to 12 months. The study aims to determine whether different low-speed drilling protocols influence peri-implant bone remodeling and implant stability.",[61,62],"Edentulism","Tooth Loss",[64,65,66,67,68,69,70],"dental implants","biological drilling","low speed drilling","marginal bone loss","implant stability","mandible","randomized clinical trial","NOT_YET_RECRUITING","2026-03-11",{"date":74,"type":75},"2026-03-16","ACTUAL",{"date":77,"type":55},"2026-03-15",{"date":79,"type":55},"2027-04-01",{"name":5,"class":6}]