[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629233":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":47,"collaborators":22,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":22,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":74,"overallStatus":38,"whyStopped":22,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Necmettin Erbakan University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Mandibular Stretching Exercise","EXPERIMENTAL","Participants perform mandibular stretching exercises according to the study protocol",[13],"Other: Mandibular Stretching Exercise",{"label":15,"type":10,"description":16,"interventionNames":17},"4-4-8 Breathing Exercise","Participants perform the 4-4-8 breathing exercise according to the study protocol",[18],"Other: 4-4-8 Breathing Exercise",[20,23],{"type":6,"name":9,"description":11,"armGroupLabels":21,"otherNames":22},[9],null,{"type":6,"name":15,"description":24,"armGroupLabels":25,"otherNames":22},"Participants perform the 4-4-8 breathing exercise according to the study protocol.",[15],[27],{"name":28,"affiliation":5,"role":29},"Neslihan Altuntaş YILMAZ, PhD","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":22,"email":35},"Mehin Mammadzada, MSc Student","CONTACT","+905313124790","mammadzadamehin01@gmail.com",[37],{"facility":5,"status":38,"city":39,"state":39,"zip":22,"country":40,"countryCode":22,"cosmosGeoPoint":41,"geoPoint":46,"contacts":22},"RECRUITING","Konya","Turkey (Türkiye)",{"type":42,"coordinates":43},"Point",[44,45],32.48464,37.87135,{"lat":45,"lon":44},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"SPONSOR_INVESTIGATOR","Mehin Mammadzada","Principal Investigator","100629233","mandibular-stretching-and-4-4-8-breathing-exercises-on-autonomic-nervous-system-activity-100629233",false,"NCT07472010","Mandibular Stretching and 4-4-8 Breathing Exercises on Autonomic Nervous System Activity","Investigation of the Effects of Mandibular Stretching Exercise and 4-4-8 Breathing Exercise on Autonomic Nervous System Activity, Muscle Tone, and Psychological State: A Randomized Controlled Trial","MSE-BR","Inclusion Criteria:\n\n* Inclusion Criteria:\n* Healthy university students\n* Age between 18 and 30 years\n* Voluntary participation in the study\n* Ability to understand and perform mandibular stretching exercise and 4-4-8 breathing exercise\n\nExclusion Criteria:\n\n* History of neurological disorders\n* Musculoskeletal disorders affecting the jaw, neck, or respiratory system\n* Respiratory diseases\n* Use of medications that may affect the autonomic nervous system\n* Inability to perform the exercises required in the study",true,"ALL","18 Years","30 Years",{"count":64,"type":65},52,"ESTIMATED","INTERVENTIONAL",[68],"NA","Mandibular stretching exercises and breathing techniques may influence autonomic nervous system activity, muscle tone, and psychological state. This randomized controlled trial aims to investigate the effects of mandibular stretching exercise and the 4-4-8 breathing exercise on autonomic nervous system activity, muscle tone, and psychological parameters in healthy university students. Participants will be randomly assigned to intervention groups and evaluated before and after the intervention period.",[71,72,73],"Muscle Tone","Psychological State","Autonomic Nervous System",[9,15,75,73,71,72],"Breathing Techniques","2026-03-11",{"date":78,"type":79},"2026-03-16","ACTUAL",{"date":81,"type":79},"2025-12-15",{"date":83,"type":65},"2026-06-19",{"name":49,"class":6},1]