[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637544":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":42,"responsibleParty":55,"collaborators":26,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":26,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":26,"enrollmentInfo":68,"targetDuration":26,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":81,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Ankara City Hospital Bilkent","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group M (Manual Ventilation)","ACTIVE_COMPARATOR","Following the standardized induction of general anesthesia (1 µg\u002Fkg fentanyl, 1 mg\u002Fkg lidocaine, 2-3 mg\u002Fkg propofol, and 0.6-1 mg\u002Fkg rocuronium), mask ventilation with 100% oxygen will be manually performed by an experienced anesthesiologist or anesthesia resident. Manual ventilation using a reservoir bag will be maintained for 2 minutes to allow for adequate muscle relaxation prior to intubation.",[13],"Procedure: Manual Mask Ventilation",{"label":15,"type":16,"description":17,"interventionNames":18},"Group A (AutoFlow Ventilation)","EXPERIMENTAL","Following the same standardized general anesthesia induction protocol, mask ventilation with 100% oxygen will be mechanically delivered by the anesthesia workstation for 2 minutes. The device will be set to deliver a tidal volume (VT) of 6 mL\u002Fkg based on the patient's ideal body weight, a respiratory rate of 12 breaths\u002Fminute, a peak inspiratory pressure limit of 30 cmH₂O, and a Positive End-Expiratory Pressure (PEEP) of 5 cmH₂O.",[19],"Procedure: AutoFlow Mechanical Mask Ventilation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Manual Mask Ventilation","Patients will receive manual mask ventilation with 100% oxygen using a reservoir bag. This procedure will be performed by an experienced anesthesiologist or anesthesia resident for 2 minutes following the administration of induction agents, allowing for adequate muscle relaxation prior to endotracheal intubation.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"AutoFlow Mechanical Mask Ventilation","Patients will receive mask ventilation delivered mechanically by the anesthesia workstation. The device will provide 100% oxygen for 2 minutes following the administration of induction agents. The ventilator settings will be standardized to an AutoFlow mode with a tidal volume (VT) of 6 mL\u002Fkg (based on ideal body weight), a respiratory rate of 12 breaths\u002Fminute, a peak pressure limit of 30 cmH₂O, and a Positive End-Expiratory Pressure (PEEP) of 5 cmH₂O",[15],[32],{"name":33,"affiliation":34,"role":35},"EYÜP HORASANLI, Professor","Ankara Bilkent City Hospital Department of Anesthesiology and Reanimation","STUDY_DIRECTOR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"FATMA G KILIÇASLAN, Resident","CONTACT","+905305692877","fatmagulgunkilicaslan@gmail.com",[43],{"facility":34,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":26,"cosmosGeoPoint":49,"geoPoint":54,"contacts":26},"RECRUITING","Ankara","Çankaya","06800","Turkey (Türkiye)",{"type":50,"coordinates":51},"Point",[52,53],32.85427,39.91987,{"lat":53,"lon":52},{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Fatma GÜLGÜN KILIÇASLAN","Resident","100637544","manual-versus-autoflow-ventilation-during-anesthesia-inducton-in-geriatric-patients-100637544",false,"NCT07582913","Manual Versus Autoflow Ventilation During Anesthesia Inductıon in Geriatric Patients","Effects of Manual Versus Autoflow Ventilation During Anesthesia Induction on Cerebral and Peripheral Oxygenation in Geriatric Patients","Inclusion Criteria:\n\n* Patients aged 65 years and older.\n* Patients scheduled to undergo elective surgery requiring endotracheal intubation under general anesthesia.\n* Patients with an American Society of Anesthesiologists (ASA) physical status of I, II, or III.\n* Volunteer patients who are willing to participate and provide written informed consent.\n\nExclusion Criteria:\n\n* Patients with severe heart failure or severe pulmonary disease.\n* Patients with a presence or history of brain tumors or cerebrovascular accidents (CVA\u002Fstroke).\n* Patients with impaired cooperation or cognitive dysfunction (e.g., dementia, delirium, Alzheimer's disease).\n* Patients with a known history or preoperative prediction of a difficult airway.\n* Patients with a known allergy to the monitoring sensor materials.","ALL","65 Years",{"count":69,"type":70},106,"ESTIMATED","INTERVENTIONAL",[73],"NA","The objective of this study is to compare the effects of manual ventilation and AutoFlow ventilation, administered during the induction of general anesthesia, on cerebral (s-rSO₂) and peripheral (somatic) oxygenation (p-rSO₂) in geriatric patients.",[76,77,78,79,80],"Cerebral Oxygenation","Peripheral Oxygenation","Geriatrics","Ventilation","Near-Infrared Spectroscopy",[78,80,82,83,84,85],"Cerebral Oximetry","Cerebral Autoregulation","Mask Ventilation","Autoflow","2026-05-13",{"date":88,"type":89},"2026-05-15","ACTUAL",{"date":86,"type":89},{"date":92,"type":70},"2026-12-05",{"name":5,"class":6},1]