[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562052":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":22,"locations":28,"responsibleParty":46,"collaborators":49,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":11,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":11,"enrollmentInfo":63,"targetDuration":11,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":30,"whyStopped":11,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Northwestern University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Shoulder Abduction","EXPERIMENTAL",null,[13],"Other: Shoulder Abduction",[15],{"type":6,"name":9,"description":16,"armGroupLabels":17,"otherNames":11},"Individuals will be visually cued to perform short, unilateral, isometric shoulder abduction tasks. A visual display will provide real-time feedback of the shoulder abduction torque, to help the participant target a predetermined torque level.",[9],[19],{"name":20,"affiliation":5,"role":21},"Molly G Bright, DPhil","PRINCIPAL_INVESTIGATOR",[23],{"name":24,"role":25,"phone":26,"phoneExt":11,"email":27},"Michelle Medina, BS","CONTACT","872-272-7687","anvil@northwestern.edu",[29],{"facility":5,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Chicago","Illinois","60611","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-87.65005,41.85003,{"lat":40,"lon":39},[43,44],{"name":24,"role":25,"phone":26,"phoneExt":11,"email":27},{"name":45,"role":21,"phone":11,"phoneExt":11,"email":11},"Molly Bright, DPhil",{"type":21,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Molly Bright","Assistant Professor",[50],{"name":51,"class":52},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH","100562052","mapping-corticoreticulospinal-motor-control-in-chronic-hemiparetic-stroke-100562052",false,"NCT06598150","Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke","Mapping Corticoreticulospinal Motor Control Using Brainstem and Spinal Cord fMRI in Chronic Hemiparetic Stroke","Inclusion Criteria:\n\n* Adults aged at least 18y\n* Able to perform shoulder abduction task (confirmed during screening and initial examination)\n* Safe to undergo MRI\n* Able to follow visual instructions using MRI-compatible vision correction goggles\n* No brainstem or cerebellar lesions\n* No severe concurrent medical problems\n* Cognitive\u002Fattentional capacity to focus on a task\n* Able to communicate in English or Spanish\n\nAdditional inclusion criteria for stroke participants:\n\n* Have sustained only one unilateral subcortical, ischemic lesion in the territory supplied by the Middle Cerebral Artery (confirmed by clinical or radiological reports) at least one year prior to participation in this project\n* Paresis confined to one side, with moderate-to-severe motor impairment of the upper limb (Upper Extremity Fugl-Meyer score between 10 and 45).\n\nExclusion Criteria:\n\n* MRI contraindications\n* Severe claustrophobia\n* Pregnant women\n* Prisoners\n* Vulnerable populations\n* Diagnosis\u002Fhistory of:\n* multiple sclerosis\n* brain tumor\n* brain radiation\n* traumatic brain injury\n* dementia\n* Parkinson's disease\n* Concurrent enrollment in an intervention study\n* Concurrent use of medications known to suppress central nervous system activity",true,"ALL","18 Years",{"count":64,"type":65},32,"ESTIMATED","INTERVENTIONAL",[68],"NA","This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.",[71,72],"Stroke","Hemiparesis",[74],"functional magnetic resonance imaging","2025-09-26",{"date":77,"type":78},"2025-10-01","ACTUAL",{"date":80,"type":78},"2023-05-20",{"date":82,"type":65},"2026-08-31",{"name":5,"class":6},1]