[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100510280":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":46,"responsibleParty":79,"collaborators":82,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":26,"eligibilityCriteria":91,"healthyVolunteers":92,"sex":93,"minAge":94,"maxAge":26,"enrollmentInfo":95,"targetDuration":26,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":104,"overallStatus":49,"whyStopped":26,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"All-on-four fixed mandibular prosthesis using conventionally screw retained multiunit abutments.","ACTIVE_COMPARATOR","Edentulous patients receiving All-on-four fixed mandibular prosthesis using conventionally screw retained multiunit abutments.",[13],"Procedure: patients reciveing all on 4 fixed mandibular prosthesis usimg conventionally screw retained multiunit abutments",{"label":15,"type":16,"description":17,"interventionNames":18},"All-on-four fixed mandibular prosthesis using OT bridge attachment system","EXPERIMENTAL","Edentulous patients receiving All-on-four fixed mandibular prosthesis using OT bridge attachment system",[19],"Procedure: all on 4 fixed mandibular prosthesis using OTbridge attachment system",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","patients reciveing all on 4 fixed mandibular prosthesis usimg conventionally screw retained multiunit abutments","Multiunit abutments is considered a gold standard screw retained abutments. Multi-unit abutments are used to correct for varying heights among the implants, to establish a level restorative platform for the prosthesis, as well as to situate the implant connection even with or just below the gingival surface. Also they are used to correct the angulation of implants, helping to keep the screw access holes away from the facial surfaces of the restoration, and facilitate the path of insertion of prosthesis.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"all on 4 fixed mandibular prosthesis using OTbridge attachment system","The OT bridge attachment system introduced by (Rhein 83) is a global, well-established system used in the removable prosthetic protocols, the presence of seeger acetal ring placed between the sub-equatorial area of the OT Equator and the cylindrical \"Extragrade\" abutment compensates the space between the extragrade abutment and the OT equator attachment correcting the minor misalignments that produced during the prosthetic procedure and resulting in more passive fit.",[15],[32],{"name":33,"affiliation":34,"role":35},"nesma O elmosallamy","CAIRO UNIVERISTY","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"nesma O elmosallamy, LECTURER ASSISTANT","CONTACT","20+01007702271","nesma.osama@dentistry.edu.eg",{"name":43,"role":39,"phone":44,"phoneExt":26,"email":45},"nada O elmosallamy","20+01000107914","nesma.elmosallamy@bue.edu.eg",[47,71],{"facility":48,"status":49,"city":50,"state":26,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Faculty of Oral and Dental Medicine, Cairo University","RECRUITING","Cairo","002","Egypt","EG",{"type":55,"coordinates":56},"Point",[57,58],31.24967,30.06263,{"lat":58,"lon":57},[61,65,69],{"name":62,"role":39,"phone":63,"phoneExt":26,"email":64},"nesma O EL mosallamy, phd candidate","000201007702271","nesma.osama@dentistry.cu.edu.eg",{"name":66,"role":39,"phone":67,"phoneExt":26,"email":68},"nesma O EL MOSALLAMY, PHD CANDIDATE","00201000107914","nesma.elmosallammy@bue.edu.eg",{"name":70,"role":35,"phone":26,"phoneExt":26,"email":26},"nesma O El mosallamy, phd candidate",{"facility":48,"status":49,"city":50,"state":26,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":72,"geoPoint":74,"contacts":75},{"type":55,"coordinates":73},[57,58],{"lat":58,"lon":57},[76],{"name":77,"role":39,"phone":78,"phoneExt":26,"email":64},"nesma O EL mosallamy, assistant lecturer","00201007702271",{"type":35,"investigatorFullName":80,"investigatorTitle":81,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Nesma osama","assistant lecturer",[83],{"name":84,"class":6},"British University In Egypt","100510280","marginal-bone-changes-in-fixed-all-on-four-mandibular-prosthesis-using-ot-bridge-attachment-system-100510280",false,"NCT05924386","Marginal Bone Changes in Fixed All-on-Four Mandibular Prosthesis Using OT Bridge Attachment System","Marginal Bone Changes in Fixed All-on-Four Mandibular Prosthesis Using OT Bridge Attachment System Versus Conventionally Screw Retained Multiunit Abutments: A Randomized Clinical Trial","Inclusion Criteria:\n\nPatients with completely edentulous patients\n\n* Aged 40 years or older.\n* Sufficient inter -arch space not less than 13 mm.\n* Good oral hygiene\n* Minimum bone height 10 mm and minimum bone diameter should be 6 mm\n\nExclusion Criteria:\n\n* General contraindications for oral surgery\n* Heavy smokers (greater than 20 cigarettes a\n* Local acute or chronic infections\n* Substance abuse (drugs or alcohol)\n* Patients with neuromuscular or psychiatric disorders.\n* Treatment with intravenous bisphosphonates\n* Irradiation of the neck or head area in the past 5 years\n* Diabetic patients (HbA1c\\>7.5%)",true,"ALL","40 Years",{"count":96,"type":97},20,"ESTIMATED","INTERVENTIONAL",[100],"NA","Group I (control) Edentulous mandible receiving all on four fixed mandibular prosthesis using conventionally screw retained multiunit abutments.\n\nGroup II (intervention) Edentulous mandible receiving all on four fixed prostheses using OT bridge attachments system.\n\nFor both groups, the implant sites will be prepared aided by the surgical template. 4 implants with length 11-13 mm will be placed, two anterior implants will be aligned in an axial orientation and two posterior implants will be distally aligned according to the all-on-four concept in the inter foraminal area. Implants will be ideally placed at bone level.\n\nFor both groups:\n\nAfter implant placement and surgical guide removal, healing abutments ( will be connected during healing periods (eight to twelve weeks).\n\nGroup I ( control) After eight to twelve weeks from implant placement, multiunit abutments with appropriate heights and angulations will be connected to the implants.\n\nGroup II ( intervention) After eight to twelve weeks from implant placement, narrow- and low-profile OT Equator abutment will be screwed onto the implants according to the manufacturer.\n\nmarginal bone changes and prosthetic complications are the outcomes Radiographic follow up will be performed for marginal bone changes Serial of standardized digital periapical radiographs using will be taken at the time fixed prosthesis insertion (baseline), 3,6,9,12 months.\n\nType and incidence of prosthetic complications for the prothesis for each group will be evaluated in 3, 6,9 and 12 months, these complications included: loosening or fracture of the prosthetic screw, prosthesis mobility and fracture of the prosthesis.",[103],"Edentulous Jaw",[105,106,107,108],"OTbridge attachment","ALL ON 4","fixed supported implant prosthesis","conventional screw retained fixed prosthesis","2025-04-23",{"date":111,"type":112},"2025-04-25","ACTUAL",{"date":114,"type":112},"2024-12-01",{"date":116,"type":97},"2026-01-31",{"name":5,"class":6},2]