[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100538849":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":103,"collaborators":105,"id":109,"slug":110,"hasResults":111,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":115,"eligibilityCriteria":116,"healthyVolunteers":111,"sex":117,"minAge":118,"maxAge":25,"enrollmentInfo":119,"targetDuration":25,"studyType":122,"phases":123,"briefSummary":125,"conditions":126,"keywords":25,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":138},{"fullName":5,"class":6},"Veterans Medical Research Foundation","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Massed PE","EXPERIMENTAL","Prolonged Exposure delivered in a massed format - sessions multiple times per week",[13],"Behavioral: Prolonged Exposure Therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Weekly PE","ACTIVE_COMPARATOR","Prolonged Exposure delivered with weekly sessions",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Prolonged Exposure Therapy","Exposure therapy for PTSD",[9,15],null,[27],{"name":28,"affiliation":29,"role":30},"Shannon Kehle-Forbes, PhD","University of Minnesota","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Sonya Norman, PhD","CONTACT","858-518-8266","snorman@ucsd.edu",{"name":38,"role":34,"phone":39,"phoneExt":25,"email":40},"Kaitlyn Panza, PhD","858-552-8585","kaitlyn.panza@va.gov",[42,60,75,89],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"VA San Diego Healthcare System","RECRUITING","San Diego","California","92161","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-117.16472,32.71571,{"lat":54,"lon":53},[57],{"name":33,"role":34,"phone":58,"phoneExt":25,"email":59},"8585188266","sonya.norman@va.gov",{"facility":61,"status":44,"city":62,"state":63,"zip":64,"country":48,"countryCode":49,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"VA Tampa Healthcare System","Tampa","Florida","33612",{"type":51,"coordinates":66},[67,68],-82.45843,27.94752,{"lat":68,"lon":67},[71],{"name":72,"role":34,"phone":73,"phoneExt":25,"email":74},"Brittany Davis, PhD","813-972-2000","brittany.davis@va.gov",{"facility":76,"status":44,"city":77,"state":78,"zip":79,"country":48,"countryCode":49,"cosmosGeoPoint":80,"geoPoint":84,"contacts":85},"VA Atlanta Healthcare System","Atlanta","Georgia","30033",{"type":51,"coordinates":81},[82,83],-84.38798,33.749,{"lat":83,"lon":82},[86],{"name":87,"role":34,"phone":25,"phoneExt":25,"email":88},"Kristin Lamp, PhD","kristen.lamp@va.gov",{"facility":90,"status":44,"city":91,"state":92,"zip":93,"country":48,"countryCode":49,"cosmosGeoPoint":94,"geoPoint":98,"contacts":99},"Hines VA Healthcare System","Chicago","Illinois","60141",{"type":51,"coordinates":95},[96,97],-87.65005,41.85003,{"lat":97,"lon":96},[100],{"name":101,"role":34,"phone":25,"phoneExt":25,"email":102},"Jonathan Bayer, PhD","jonathan.bayer2@va.gov",{"type":104,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[106,107],{"name":29,"class":6},{"name":108,"class":6},"Center for Veterans Research and Education","100538849","massed-prolonged-exposure-for-ptsd-in-substance-use-treatment-100538849",false,"NCT06296186","Massed Prolonged Exposure for PTSD in Substance Use Treatment","Clinical Effectiveness and Implementation of Massed Prolonged Exposure for PTSD Among Veterans in Intensive Outpatient Substance Use Treatment (MPE)","PREVAIL","Inclusion Criteria:\n\n* Veterans\n* age 18+\n* who have served since September 2001\n* who are enrolled in a SUD IOP at a participating VA\n* meet DSM-5 criteria for a current SUD (Tobacco Use Disorder alone not sufficient for inclusion)\n* meet DSM-5 criteria for PTSD\n* report substance use at least 20 of the last 90 days\n* are able to give informed consent.\n\nExclusion Criteria:\n\n* severe cognitive impairment\n* current suicidal or homicidal intent requiring immediate treatment\n* current unstable psychotic or manic symptoms not attributable to SUD","ALL","18 Years",{"count":120,"type":121},200,"ESTIMATED","INTERVENTIONAL",[124],"NA","The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and substance use disorder in intensive outpatient substance use treatment. The main questions it aims to answer are:\n\n* Will the massed format help participants complete and benefit from Prolonged Exposure in terms of PTSD symptoms?\n* Will it help participants reduce substance use? Participants who are in intensive substance use treatment will be asked to complete Prolonged Exposure with either weekly sessions or multiple sessions per week.",[127,128],"Stress Disorders, Post-Traumatic","Substance Use Disorders","2025-04-16",{"date":131,"type":132},"2025-04-22","ACTUAL",{"date":134,"type":132},"2024-09-01",{"date":136,"type":121},"2027-08",{"name":5,"class":6},4]