[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100334345":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":10,"centralContacts":15,"locations":24,"responsibleParty":42,"collaborators":45,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":7,"studyType":64,"phases":7,"briefSummary":65,"conditions":66,"keywords":72,"overallStatus":26,"whyStopped":7,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Guangzhou Women and Children's Medical Center","OTHER",null,[9],{"type":6,"name":7,"description":7,"armGroupLabels":7,"otherNames":7},[11],{"name":12,"affiliation":13,"role":14},"Xiu Qiu, PhD","Guangzhou Women and Children's Medical Center, China","PRINCIPAL_INVESTIGATOR",[16,20],{"name":12,"role":17,"phone":18,"phoneExt":7,"email":19},"CONTACT","0086 20 38367160","qxiu0161@163.com",{"name":21,"role":17,"phone":22,"phoneExt":7,"email":23},"Xueling Wei, MS","0086 20 38367159","xueling.wei@bigcs.org",[25],{"facility":5,"status":26,"city":27,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"RECRUITING","Guangzhou","Guangdong","510623","China","CN",{"type":33,"coordinates":34},"Point",[35,36],113.25,23.11667,{"lat":36,"lon":35},[39],{"name":40,"role":17,"phone":41,"phoneExt":7,"email":19},"Xiu Qiu, Doctor","+862038076001",{"type":14,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Xiu Qiu","Director of the Born in Guangzhou Cohort Study",[46,48],{"name":47,"class":6},"Children's Hospital Medical Center, Cincinnati",{"name":49,"class":6},"University of Birmingham","100334345","maternal-grandmothers-in-the-born-in-guangzhou-cohort-study-100334345",false,"NCT03633162","Maternal Grandmothers in the Born in Guangzhou Cohort Study","MGBIG","Inclusion Criteria:\n\n1. Maternal Grandmother' grandchildren delivered in Guangzhou Women and Children's Medical Center\n2. Baseline information of maternal grandmother's daughter during pregnancy available\n\nExclusion Criteria:\n\n1. Significant cardiovascular abnormalities\n2. Intelligent obstacle, intellectual disabilities or gawkish condition",true,"FEMALE","36 Years","100 Years",{"count":62,"type":63},5000,"ESTIMATED","OBSERVATIONAL","The MGBIG is a study exploring cross-generational effects in 5000 women and their children and grandchildren located in Guangzhou, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology and on explaining the cause of the disease from the perspective of \"grandmother-mother-child\" heredity. Data are collected regarding environmental exposures, lifestyle, and social support on grandmother from birth to old age. Biological samples including blood and tissue samples are collected.",[67,68,69,70,71],"Hereditary Transmission","Immune Development","Childhood Obesity","Host and Microbiome","Neurodevelopment",[73,74,75,76,77],"Maternal Grandmother","Genes","Immune","Cohort","Child development","2024-09-27",{"date":80,"type":81},"2024-10-01","ACTUAL",{"date":83,"type":81},"2018-05-21",{"date":85,"type":63},"2038-12-31",{"name":5,"class":6},1]