[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100535461":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":17,"centralContacts":30,"locations":36,"responsibleParty":55,"collaborators":17,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":17,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":17,"enrollmentInfo":68,"targetDuration":17,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":79,"overallStatus":39,"whyStopped":17,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Brigham and Women's Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"1. Interventional group","EXPERIMENTAL","subjects who are being consented to this study and undergoing lymph node dissection as outlined in this protocol",[13],"Other: Subjects undergoing a lung specimen lymph node dissection",{"label":15,"type":16,"description":17,"interventionNames":17},"Concurrent non-interventional group","NO_INTERVENTION",null,{"label":19,"type":6,"description":17,"interventionNames":20},"Retrospective cohort from 2021-2020",[21],"Other: Control group",[23,27],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":17},"Subjects undergoing a lung specimen lymph node dissection","A lobectomy specimen's resection will undergo systematic lymph node dissection either by the patient's treating thoracic surgeon and\u002For by a member of the pathology team.\n\nThe protocol for a standardized lymph node dissection consists of a series of blunt peribronchial dissections starting from the hilum to the periphery, with particular attention to points of airway bifurcation where intrapulmonary lymph nodes aggregate. By emphasizing the intrapulmonary lymph node map and a standardized dissection, the team will remove more lymph nodes from the lobectomy specimen, resulting in an accurate N staging.",[9],{"type":6,"name":28,"description":28,"armGroupLabels":29,"otherNames":17},"Control group",[19],[31],{"name":32,"role":33,"phone":34,"phoneExt":17,"email":35},"Paula Ugalde Figueroa, M.D.","CONTACT","(617) 732-7696","pugaldefigueroa@bwh.harvard.edu",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Brigham and Womens Hospital","RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-71.05977,42.35843,{"lat":49,"lon":48},[52],{"name":53,"role":33,"phone":54,"phoneExt":17,"email":35},"Paula Ugalde Figueroa THORACIC SURGEON, MD","617-794-6491",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","Paula Antonia Ugalde Figueroa","Associate Surgeon, Division of Thoracic Surgery, Principal Investigator.","100535461","maximizing-lymph-node-dissection-on-fresh-and-fixed-lung-cancer-resection-specimens-100535461",false,"NCT06252129","Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens","Inclusion Criteria:\n\n1. Subjects with a lung nodule or mass who are eligible to undergo a lobectomy.\n2. Subject without any metastasis present.\n3. Subjects who have peripheral lung nodule location\n4. Subjects must be 18 years of age or older.\n\nExclusion Criteria:\n\n1. Subjects who received preoperative chemotherapy or radiotherapy.\n2. Subjects who have a lung nodule located in a central location. Central tumors are defined by those infiltrating the lobar airway.",true,"ALL","18 Years",{"count":69,"type":70},160,"ESTIMATED","INTERVENTIONAL",[73],"NA","Lung cancer patients undergoing upfront surgery, highly benefit from a systematic lymph node dissection in the mediastinum and in the surgical specimens. The latter is performed by the pathologist. Developing a standardized technique to dissect the lobectomy specimen has the potential of maximizing the retrieval of all N1 stations lymph nodes. The investigators believe that the adoption of such technique will improve lung cancer staging and identify a higher number of patients that qualify for adjuvant therapies.",[76,77,78],"Lung Cancer","Lymph Node Metastasis","Pathologic Processes",[80,81,82],"NSCLC","Lymph node dissection","Lung cancer staging","2026-03-03",{"date":85,"type":86},"2026-03-05","ACTUAL",{"date":88,"type":86},"2024-07-26",{"date":90,"type":70},"2027-12",{"name":5,"class":6},1]