[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631797":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":25,"responsibleParty":79,"collaborators":10,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":10,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":10,"studyType":96,"phases":10,"briefSummary":97,"conditions":98,"keywords":100,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Hasselt University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Multiple Sclerosis",null,"People presenting with multiple sclerosis diagnosis according to the revised Mcdonald's criteria.",{"label":13,"type":10,"description":14,"interventionNames":10},"Healthy control group","Age and sex matching is ensured within a five-year range per healthy control",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Zuhal Abasiyanik, PhD","CONTACT","+32(0)11 26 93 06","zuhal.abasiyanik@uhasselt.be",{"name":22,"role":18,"phone":23,"phoneExt":10,"email":24},"Peter Feys","+32(0)11 26 21 23","peter.feys@uhasselt.be",[26,41,56,72],{"facility":27,"status":28,"city":29,"state":10,"zip":10,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"REVAL Rehabilitation Research Center","RECRUITING","Diepenbeek","Belgium","BE",{"type":33,"coordinates":34},"Point",[35,36],5.41875,50.90769,{"lat":36,"lon":35},[39],{"name":22,"role":18,"phone":40,"phoneExt":10,"email":24},"+32 11 29 21 23",{"facility":42,"status":28,"city":43,"state":10,"zip":10,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":50,"contacts":51},"Laboratorio di Biomeccanica ed Ergonomia industriale Università degli Studi di Cagliari","Cagliari","Italy","IT",{"type":33,"coordinates":47},[48,49],9.11917,39.23054,{"lat":49,"lon":48},[52],{"name":53,"role":18,"phone":54,"phoneExt":10,"email":55},"Massimiliano Pau","+39 338 782 5240","massimiliano.pau@unica.it",{"facility":57,"status":28,"city":58,"state":59,"zip":10,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"Hospital Universitario de Ponferrada El Bierzo","León","Ponferrada","Spain","ES",{"type":33,"coordinates":63},[64,65],-5.57032,42.60003,{"lat":65,"lon":64},[68],{"name":69,"role":18,"phone":70,"phoneExt":10,"email":71},"María Mercedes Reguera García, PhD","(+34) 987 442000","mercedes.reguera@unileon.es",{"facility":73,"status":28,"city":58,"state":59,"zip":10,"country":60,"countryCode":61,"cosmosGeoPoint":74,"geoPoint":76,"contacts":77},"University of Leon",{"type":33,"coordinates":75},[64,65],{"lat":65,"lon":64},[78],{"name":69,"role":18,"phone":70,"phoneExt":10,"email":71},{"type":80,"investigatorFullName":22,"investigatorTitle":81,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Prof. dr.","100631797","measurement-properties-of-the-walking-adaptability-ladder-test-and-foot-tap-test-in-multiple-sclerosis-100631797",false,"NCT07505355","Measurement Properties of the Walking Adaptability Ladder Test and Foot Tap Test in Multiple Sclerosis","Measurement Properties of the Walking Adaptability Ladder Test and Foot Tap Test in People With Multiple Sclerosis With Mild Disability","Inclusion Criteria:\n\n* confirmed diagnosis of definite MS,\n* relapse free at least 30 days,\n* Expanded Disability Status Scale (EDSS) score between 0 and 3.5\n\nExclusion Criteria:\n\n* diagnosed with neurological disease other than MS\n* cognitive decline that renders the patient incapable of performing tests and questionnaires.\n* other neurological, orthopedic, or visual impairments affecting gait",true,"ALL","18 Years","65 Years",{"count":94,"type":95},100,"ESTIMATED","OBSERVATIONAL","Walking and motor control impairments are among the most common manifestations experienced by people with multiple sclerosis (pwMS) and may already be present in individuals with mild disability. Subtle changes in walking performance can reflect early disease progression, highlighting the need for sensitive clinical outcome measures that capture complex, real-world mobility. Commonly used assessments primarily quantify time or distance and may lack sensitivity to detect early or subtle functional changes in daily-life walking. Successful everyday mobility requires gait adaptability, defined as the ability to continuously adjust walking patterns in response to environmental or task-related challenges, including the processing of external perturbations and internal factors such as fatigue, balance confidence, and fear of falling. Despite its clinical relevance, gait adaptability is not specifically addressed by currently validated clinical tests in pwMS. The Walking Adaptability Ladder Test (WALT), which challenges the interaction between step length, cadence, and walking speed through continuous adjustments, and the Foot Tap Test (FTT), which assesses lower limb motor control and rhythmic coordination, have demonstrated promising measurement properties in other populations but have not yet been evaluated in pwMS. The primary aim of this study is to examine the test-retest reliability and construct validity of the WALT and FTT in pwMS with mild disability. Secondary aims include evaluating the measurement properties of the Balance Recovery Scale and the Gait-Specific Attention Scale in pwMS with mild disability, identifying inertial measurement unit-derived metrics that best discriminate pwMS with low disability from healthy controls, and exploring whether relationships between clinical motor test outcomes and self-reported measures provide complementary insights into subtle gait impairments.",[9,99],"Healthy Controls Group - Age and Sex-matched",[101,102,103,104,105,106],"multiple sclerosis","walking","tapping","motor function","walking adaptability","falls","2026-03-26",{"date":109,"type":110},"2026-04-01","ACTUAL",{"date":112,"type":110},"2025-11-10",{"date":114,"type":95},"2026-12-01",{"name":5,"class":6},4]