[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100440221":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":27,"responsibleParty":44,"collaborators":48,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":20,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":20,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":30,"whyStopped":20,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Georgetown University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants","EXPERIMENTAL","The study involves a pre-intervention phase (4 weeks long), followed by a cause and effect training phase (1 week long), followed by an intervention phase (12 weeks long), and ending with a post-intervention phase (4-weeks long) for a total of 5-6 months from start to finish.",[13],"Behavioral: Modified Virtual Reality Gaming",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","Modified Virtual Reality Gaming","Investigators customize each gaming session based on the motivators and interests of each participant. The intervention facilitates independent hand separations (minimizing stereotypies) and encourages independent arm\u002Fhand movement that serves to activate or control the computer-generated activities.",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Pamela S Diener, PhD, MS, OT\u002FL","CONTACT","2403811763","psd23@georgetown.edu",[28],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Georgetown University School of Medicine","RECRUITING","Washington D.C.","District of Columbia","20057","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-77.03637,38.89511,{"lat":40,"lon":39},[43],{"name":23,"role":24,"phone":20,"phoneExt":20,"email":20},{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Pamela Diener","Professor",[49],{"name":50,"class":6},"International Rett Syndrome Foundation","100440221","measuring-impact-of-computer-gaming-on-arm-use-in-rett-syndrome-100440221",false,"NCT05012475","Measuring Impact of Computer Gaming on Arm Use in Rett Syndrome","Assessing the Effectiveness of Customized Computer Activities on Reducing Stereotypies and Improving Independent Upper Extremity Motor Skills in Persons with Rett Syndrome","Inclusion Criteria:\n\n* Rett syndrome,\n* Understanding of cause and effect,\n* Functional range of motion of arms to complete the movements needed to control the games.\n\nExclusion Criteria:\n\n* no competing orthopedic or neuromuscular diagnosis that impacts shoulder movements","ALL","4 Years","60 Years",{"count":62,"type":63},10,"ESTIMATED","INTERVENTIONAL",[66],"NA","Using a tele-research approach, we will recruit, enroll, guide and support carers and participants to engage in computer based activities (modified virtual reality) with the primary outcome of reducing stereotypies and increasing independent arm and hand use and secondary outcome of improving quality of living. Because of our virtual approach, we are able to recruit from multiple countries and all states and territories of the USA.",[69],"Rett Syndrome",[71,72,73,74],"enrichment","sensory stimulation","motor recovery","upper extremity function","2024-10-01",{"date":77,"type":78},"2024-10-03","ACTUAL",{"date":80,"type":78},"2021-05-01",{"date":82,"type":63},"2025-12-01",{"name":5,"class":6},1]