[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634043":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":49,"collaborators":25,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":25,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":25,"enrollmentInfo":63,"targetDuration":25,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":25,"overallStatus":74,"whyStopped":25,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Ankara City Hospital Bilkent","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Mechanical Power-Targeted Ventilation","EXPERIMENTAL","Patients receive ventilation adjusted to achieve the lowest possible mechanical power (≤14 J\u002Fmin) by titrating PEEP and respiratory rate.",[13,14],"Procedure: Mechanical Power-Targeted Ventilation","Procedure: Standard Ventilation",{"label":16,"type":17,"description":18,"interventionNames":19},"Standard Ventilation","ACTIVE_COMPARATOR","Patients receive conventional ventilation with fixed PEEP (5 cmH₂O) and routine ventilator settings.",[13,14],[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Ventilation adjusted to achieve the lowest possible mechanical power (≤14 J\u002Fmin) using titration of PEEP and respiratory rate.",[9,16],null,{"type":22,"name":16,"description":27,"armGroupLabels":28,"otherNames":25},"Conventional ventilation strategy with fixed PEEP (5 cmH₂O) and routine settings.",[9,16],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Betül Güven Aytaç, Assos Prof","CONTACT","0905073578351","drbguven@hotmail.com",[36],{"facility":37,"status":25,"city":38,"state":25,"zip":25,"country":39,"countryCode":25,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Ankara Bilkent City Hospital","Ankara","Turkey (Türkiye)",{"type":41,"coordinates":42},"Point",[43,44],32.85427,39.91987,{"lat":44,"lon":43},[47],{"name":48,"role":32,"phone":33,"phoneExt":25,"email":34},"Betül Güven Aytaç, Assos prof",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Betül Güven","Assos. Prof","100634043","mechanical-power-ventilation-in-ralp-100634043",false,"NCT07534553","Mechanical Power Ventilation in RALP","Mechanical Power-Targeted Ventilation in Robot-Assisted Laparoscopic Radical Prostatectomy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥18 years\n* Elective RALP\n* ASA I-III\n\nExclusion Criteria:\n\n* Severe pulmonary disease (advanced COPD, ILD)\n\n  * Preoperative oxygen requirement\n  * Emergency surgery\n  * BMI \\> 40 kg\u002Fm²",true,"MALE","18 Years",{"count":64,"type":65},80,"ESTIMATED","INTERVENTIONAL",[68],"NA","Robot-assisted laparoscopic radical prostatectomy (RALP) requires steep Trendelenburg positioning and pneumoperitoneum, which adversely affect respiratory mechanics and may lead to impaired postoperative oxygenation.\n\nMechanical power (MP) has recently emerged as a comprehensive parameter reflecting the total energy delivered from the ventilator to the respiratory system and may be associated with ventilator-induced lung injury.\n\nThis prospective randomized controlled trial aims to evaluate whether a mechanical power-targeted ventilation strategy improves postoperative oxygenation compared to standard ventilation in patients undergoing RALP.\n\nThe primary outcome is the oxygenation index (OSI) at the postoperative second hour. Secondary outcomes include PaO₂\u002FFiO₂ ratio, postoperative pulmonary complications, and length of hospital stay.",[71,72,73],"Postoperative Pulmonary Dysfunction","Oxygenation Impairment","Robot-Assisted Radical Prostatectomy","NOT_YET_RECRUITING","2026-04-10",{"date":77,"type":78},"2026-04-16","ACTUAL",{"date":80,"type":65},"2026-04-15",{"date":82,"type":65},"2026-07-30",{"name":5,"class":6},1]