[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556803":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":29,"locations":39,"responsibleParty":52,"collaborators":56,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":10,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":10,"overallStatus":77,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Bispebjerg Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Ischemia and no obstructive coronary arteries",null,"patients with angina and reduced myocardial blood flow reserve",[13],"Diagnostic Test: [15O]H2O-PET Imaging",{"label":15,"type":10,"description":16,"interventionNames":17},"Control","controls without angina",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","[15O]H2O-PET Imaging","This imaging technique will be used to measure myocardial blood flow (MBF) and myocardial blood flow reserve (MBFR) in patients. The PET-CT scan involves the use of the radioactive tracer \\[15O\\]H2O to visualize blood flow in the heart, providing crucial data on coronary microvascular function.",[15,9],[25],{"name":26,"affiliation":27,"role":28},"Ylva Hellsten, Professor","University of Copenhagen","STUDY_CHAIR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Eva Prescott, MD, DMSc","CONTACT","22572614","Eva.Irene.Bossano.Prescott@regionh.dk",{"name":36,"role":32,"phone":37,"phoneExt":10,"email":38},"Mads Fischer, Ph.D.","24485450","mf@nexs.ku.dk",[40],{"facility":41,"status":10,"city":42,"state":10,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":10},"Frederiksberg Hospital, Dept. of Cardiology, Building 16, Y3, Nordre Fasanvej 57, Frederiksberg, Denmark, 2000","Copenhagen","2400","Denmark","DK",{"type":47,"coordinates":48},"Point",[49,50],12.56553,55.67594,{"lat":50,"lon":49},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Eva Prescott","MD Clinical Professor",[57],{"name":27,"class":6},"100556803","mechanisms-behind-microvascular-dysfunction-in-inoca-100556803",false,"NCT06529861","Mechanisms Behind Microvascular Dysfunction in INOCA","Identification of Mechanisms Behind Microvascular Dysfunction in Ischemia With No Obstructive Coronary Artery Disease","ExINOCA-P1","Inclusion Criteria:\n\nOnly for angina patients: Have CMD, defined as myocardial bloodflow re-serve (MBFR) \\\u003C 2.5 or hyperemic myocardial blood flow (hMBF) \\\u003C 2.3ml\u002Fg\u002Fmin\n\nExclusion Criteria:\n\n* Females of childbearing potential (defined as a premeno-pausal female capable of becoming pregnant). The female patient must either be postmenopausal, defined as amen-orrhea for at least 1 year, or surgically sterile\n* Heart failure, defined as left ventricular ejection fraction of less than 40%\n* Uncontrolled hypertension defined as blood pressure above target 140\u002F90 for all\n* Co-morbidity resulting in \\\u003C1 year expected survival\n* Considered by the investigator, for any reason, to be an unsuitable candidate for the study.\n* Unable or unwilling to exercise, e.g. due to arthritis or injury\\*\n* Already are regularly physically active and\u002For have a maximal oxygen uptake \\>45 ml\u002Fkg\u002Fmin\n* The subject has a known allergy to either: norepinephrine, adenosine, ketorolac, and or ascorbic acid (vitamin C).",true,"ALL","50 Years",{"count":70,"type":71},60,"ESTIMATED","OBSERVATIONAL","The purpose of the study is to identify the causes of chest pain in patients experiencing chest pain with no signs of narrowing in the coronary arteries of the heart.",[75,76],"Coronary Microvascular Dysfunction","Ischaemia With Non Obstructed Coronary Arteries","NOT_YET_RECRUITING","2024-07-29",{"date":80,"type":81},"2024-07-31","ACTUAL",{"date":83,"type":71},"2024-10-01",{"date":85,"type":71},"2028-05-15",{"name":5,"class":6},1]