[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627861":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":11,"responsibleParty":28,"collaborators":30,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":37,"acronym":38,"eligibilityCriteria":39,"healthyVolunteers":35,"sex":40,"minAge":41,"maxAge":42,"enrollmentInfo":43,"targetDuration":10,"studyType":46,"phases":10,"briefSummary":47,"conditions":48,"keywords":51,"overallStatus":54,"whyStopped":10,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":64},{"fullName":5,"class":6},"Guy's and St Thomas' NHS Foundation Trust","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":10},"Patients with HCM and AF",null,[12],{"facility":5,"status":10,"city":13,"state":10,"zip":10,"country":14,"countryCode":15,"cosmosGeoPoint":16,"geoPoint":21,"contacts":22},"London","United Kingdom","UK",{"type":17,"coordinates":18},"Point",[19,20],-0.12574,51.50853,{"lat":20,"lon":19},[23],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"Magdalena Klis","CONTACT","02071887188","magda.klis@kcl.ac.uk",{"type":29,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[31],{"name":32,"class":6},"King's College London","100627861","mechanisms-of-atrial-pathoelectrophysiology-in-hcm-100627861",false,"NCT07454135","Mechanisms of Atrial Pathoelectrophysiology in HCM","MAP HCM","Inclusion Criteria:\n\n* Paroxysmal or persistent atrial fibrillation\n* Diagnosis of hypertrophic cardiomyopathy\n* Patient planning to proceed to atrial fibrillation ablation following clinical consultation\n* Age 18-80 years\n* Able and willing to provide written informed consent\n* Able and willing to comply with study follow up requirements\n\nExclusion Criteria:\n\n* Any clinical contra-indication to ablation\n* Any disease limiting life expectancy to \\\u003C1 year\n* Potential participant currently pregnant or breast feeding\n* Contraindication to MRI including renal dysfunction (eGFR\\\u003C30ml\u002Fmin)\n* Unable to understand verbal or written explanations given in English","ALL","18 Years","80 Years",{"count":44,"type":45},40,"ESTIMATED","OBSERVATIONAL","This study aims to learn why atrial fibrillation (AF), a type of irregular heartbeat, happens more often and is harder to treat in people with hypertrophic cardiomyopathy (HCM). HCM is an inherited condition where the heart muscle is thicker than usual.\n\nResearchers will study electrical signals from the heart and advanced heart imaging. By doing this, they hope to better understand how AF behaves in people with HCM and why treatments may not work as well for them.\n\nThe information from this study may help improve future treatments for people who have both HCM and AF.",[49,50],"Hypertrophic Cardiomyopathy (HCM)","Atrial Fibrillation (AF)",[52,53],"hypertrophic cardiomyopathy","atrial fibrillation","NOT_YET_RECRUITING","2026-03-31",{"date":57,"type":58},"2026-04-06","ACTUAL",{"date":60,"type":45},"2026-03-08",{"date":62,"type":45},"2027-09-30",{"name":5,"class":6},1]