[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560349":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":43,"responsibleParty":62,"collaborators":65,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":25,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":25,"overallStatus":91,"whyStopped":25,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Jozef Stefan Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Heat acclimation and exercise group","EXPERIMENTAL","Experimental group who will complete an exercise training intervention under hot conditions",[13],"Other: Heat acclimation and exercise training",{"label":15,"type":16,"description":17,"interventionNames":18},"Thermo-neutral exercise training group","ACTIVE_COMPARATOR","Control group who will complete an exercise training intervention under thermo-neutral conditions",[19],"Other: Thermo-neutral exercise training group",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Heat acclimation and exercise training","10-day intervention consisting of daily 60-min exercise sessions aimed to induce increases in core body temperature, conducted in a climactic chamber set to 35°C and 50% relative humidity.",[9],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"10-day intervention consisting of daily 60-min exercise sessions conducted in a climactic chamber set to 23°C and 50% relative humidity.",[15],[30],{"name":31,"affiliation":32,"role":33},"Tadej Debevec, PhD","University of Ljubljana","PRINCIPAL_INVESTIGATOR",[35,39],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","+38615207726","tadej.debevec@fsp.uni-lj.si",{"name":40,"role":36,"phone":41,"phoneExt":25,"email":42},"Benjamin J Narang, MSci","+38640569967","benjamin.narang@ijs.si",[44,58],{"facility":5,"status":25,"city":45,"state":46,"zip":47,"country":48,"countryCode":46,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Ljubljana","SI","1000","Slovenia",{"type":50,"coordinates":51},"Point",[52,53],14.50513,46.05108,{"lat":53,"lon":52},[56],{"name":57,"role":36,"phone":41,"phoneExt":25,"email":42},"Benjamin Narang, MSci",{"facility":32,"status":25,"city":45,"state":25,"zip":47,"country":48,"countryCode":46,"cosmosGeoPoint":59,"geoPoint":61,"contacts":25},{"type":50,"coordinates":60},[52,53],{"lat":53,"lon":52},{"type":33,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Tadej Debevec","Professor",[66,67],{"name":32,"class":6},{"name":68,"class":6},"University of Ljubljana, Faculty of Medicine","100560349","mechanisms-underlying-hypoxic-heat-and-cross-tolerance-adaptation-in-women-100560349",false,"NCT06575985","Mechanisms Underlying Hypoxic, Heat and Cross-tolerance Adaptation in Women","Investigating the Effects of a 10-day Heat Acclimation and Exercise Intervention on Physiological Adaptations and Cross-tolerance in Women","FemAdapt_HOT","Inclusion Criteria:\n\n* Age: 18 - 35 years\n* Body mass index: 18.5 - 25.0 kg\u002Fm\\^2\n* Regular physical activity (at least 30 minutes of moderate-intensity activity, three times per week)\n\nExclusion Criteria:\n\n* Habitual smoker within the past 5 years\n* History of metabolic disorders or any medications deemed to pose an undue risk or introduce bias in any outcome measures\n* Exposure to altitude \\> 2000 m above sea level within four weeks of scheduled participation\n* Permanent residence at altitude \\> 1000 m above sea level",true,"FEMALE","18 Years","35 Years",{"count":82,"type":83},30,"ESTIMATED","INTERVENTIONAL",[86],"NA","This study will consist of a parallel-groups design, with 30 healthy active female participants randomly assigned to either an experimental heat acclimation and exercise intervention, or a thermo-neutral exercise intervention control group. Interventions will be 10 days in duration, and consist of daily 60-minute exercise bouts under the appropriate environmental condition. Before and after each intervention, various tests will be conducted to establish exercise capacity under various environmental conditions, as well as underlying mechanisms of physiological adaptation induced by each intervention.",[89,90],"Heat Exposure","Exercise Training","NOT_YET_RECRUITING","2024-08-26",{"date":94,"type":95},"2024-08-28","ACTUAL",{"date":97,"type":83},"2024-10",{"date":99,"type":83},"2024-12",{"name":5,"class":6},2]