[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100116157":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":33,"responsibleParty":65,"collaborators":10,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":70,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":10,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of Pittsburgh","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Chronic wound study",null,"Patients with diabetes or no diabetes",[13],"Other: Blood draw",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Blood draw","Blood will be drawn from subjects once and VAC sponge will be collected (which is normally discarded material per standard of care).",[9],[20],{"name":21,"affiliation":5,"role":22},"Sashwati Roy, Ph.D.","PRINCIPAL_INVESTIGATOR",[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Piya Das Ghatak, PhD, MS","CONTACT","412-648-8297","pid12@pitt.edu",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},"Urmila Gnyawali","4126240422","USG2@pitt.edu",[34,56],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"UPMC Montefiore","RECRUITING","Pittsburgh","Pennsylvania","15219","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-79.99589,40.44062,{"lat":46,"lon":45},[49,53],{"name":50,"role":26,"phone":51,"phoneExt":10,"email":52},"CeCe Zamarripa, RN","412-647-7728","zamarripaca@upmc.edu",{"name":54,"role":26,"phone":31,"phoneExt":10,"email":55},"Piya Das Ghatak, PhD","piya.dasghatak@pitt.edu",{"facility":57,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":58,"geoPoint":60,"contacts":61},"UPMC Presbyterian",{"type":43,"coordinates":59},[45,46],{"lat":46,"lon":45},[62,64],{"name":63,"role":26,"phone":51,"phoneExt":10,"email":52},"Cecilia Zamarripa, RN",{"name":54,"role":26,"phone":27,"phoneExt":10,"email":28},{"type":22,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Sashwati Roy","Professor","100116157","mechanisms-underlying-impaired-diabetic-wound-healing-100116157",false,"NCT00777712","Mechanisms Underlying Impaired Diabetic Wound Healing","Mechanisms Underlying Impaired Wound Healing","WoundVAC","Inclusion Criteria:\n\n* Ages 21-80\n* Chronic Wound (present \\>4 weeks)\n* Diabetic \\& Non-diabetic\n* Adult surgical wounds\n\nExclusion Criteria:\n\n* Inability to consent\n* Pregnant women\n* Therapeutically immunocompromised\n* Individuals defined in 45 CFR 46 Subparts B,C, and D, nor from any other population considered vulnerable 2.9","ALL","21 Years","80 Years",{"count":80,"type":81},250,"ESTIMATED","OBSERVATIONAL","The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.",[85],"Non-healing Wound",[87,88,89,90,91,92],"Wound healing","diabetes","inflammatory cell","monocyte","leukocyte","macrophage","2026-06-03",{"date":95,"type":96},"2026-06-05","ACTUAL",{"date":98,"type":96},"2008-09-01",{"date":100,"type":81},"2030-12-31",{"name":5,"class":6},2]