[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100316346":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":39,"responsibleParty":58,"collaborators":18,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":18,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":18,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":18,"overallStatus":41,"whyStopped":18,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Virginia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention","EXPERIMENTAL","CMR-Guided CRT",[13],"Diagnostic Test: CMR\u002FCTA Guidance for CRT",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Standard CRT",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DIAGNOSTIC_TEST","CMR\u002FCTA Guidance for CRT","The intervention is the use of CMR and CTA to determine the optimal pacing site in the left ventricle for cardiac resynchronization therapy (CRT) and guide left ventricular lead placement.",[9],[26],{"name":27,"affiliation":28,"role":29},"Kenneth C Bilchick, MD","University of Virginia Health System","PRINCIPAL_INVESTIGATOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":18,"email":34},"CONTACT","4349242465","bilchick@virginia.edu",{"name":36,"role":32,"phone":37,"phoneExt":18,"email":38},"Hollis Phillips, BA","434-243-0046","hp9r@hscmail.mcc.virginia.edu",[40],{"facility":28,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Charlottesville","Virginia","22908","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-78.47668,38.02931,{"lat":51,"lon":50},[54],{"name":55,"role":32,"phone":56,"phoneExt":18,"email":57},"John Hoover","434-243-4861","jrh5r@hscmail.mcc.virginia.edu",{"type":29,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Kenneth Bilchick, MD","Associate Professor of Medicine","100316346","mechanistic-clinical-trial-of-advanced-imaging-for-crt-100316346",false,"NCT03398369","Mechanistic Clinical Trial of Advanced Imaging for CRT","Advanced Imaging and Inflammatory Markers to Define Mechanisms of Response to CRT","Inclusion Criteria:\n\n1. Chronic systolic HF\n2. LVEF 35% or less\n3. Guideline-based class I or II indication for CRT\n\nExclusion Criteria:\n\n1. Inability to provide informed consent\n2. Pregnancy\n3. Presence of metal embedded in the body due to prior accident or injury, as documented by skull films or other imaging\n4. Cerebral aneurysm clips\n5. Cochlear implants\n6. Other metallic implants known to be contraindications to CMR (does not include pacemakers and ICDs)\n7. Severe claustrophobia\n8. Acute kidney injury\n9. Acute renal failure or chronic kidney disease with GFR \\\u003C 45 cc\u002Fmin\u002F1.73m2\n10. Liver transplant\n11. Gadolinium allergy\n12. \\>10% premature ventricular contraction (PVC) burden; and 13) estimated \\>10% atrial fibrillation (AF) burden based on available clinical data.","ALL","20 Years","90 Years",{"count":72,"type":73},180,"ESTIMATED","INTERVENTIONAL",[76],"NA","This is a mechanistic clinical trial with randomization to guidance for the CRT procedure using cardiac magnetic resonance (CMR) and computed tomography angiography (CTA) versus a standard procedure.",[79],"Heart Failure, Systolic","2020-02-04",{"date":82,"type":83},"2020-02-06","ACTUAL",{"date":85,"type":83},"2018-01-05",{"date":87,"type":73},"2025-01-15",{"name":5,"class":6},1]