[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637823":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":29,"locations":35,"responsibleParty":72,"collaborators":24,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":76,"sex":82,"minAge":83,"maxAge":24,"enrollmentInfo":84,"targetDuration":24,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":38,"whyStopped":24,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Maasstad Hospital","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"carpal tunnel release","Control group",[12],"Procedure: Carpal tunnel release",{"label":14,"type":6,"description":15,"interventionNames":16},"carpal tunnel release combined with Lacertus release","Intervention group",[17],"Procedure: Combined carpal tunnel and lacertus release",[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Carpal tunnel release","Carpal tunnel release is a surgical procedure to treat carpal tunnel syndrome by cutting the ligament (transverse carpal ligament) covering the wrist's carpal tunnel. This action relieves pressure on the median nerve, alleviating pain, numbness, and weakness in the hand. It is usually an outpatient procedure done under local anesthesia.",[9],null,{"type":20,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Combined carpal tunnel and lacertus release","A transverse incision is made on the forearm's volar (anterior) aspect, approximately 3cm distal of the elbow crease. This incision is placed over the palpable brachioradialis and biceps tendon. The subcutaneous tissue is dissected to expose the fascia overlying the flexor pronator muscles. The brachial fascia is identified and incised to reveal the underlying Lacertus fibrosus (also known as the bicipital aponeurosis). The Lacertus fibrosus is a tendinous band extending from the biceps tendon medially across the forearm. Care is taken to avoid injury to the underlying structures, particularly the median nerve, which lies deep and slightly medial to the Lacertus fibrosus. The Lacertus fibrosus is incised transversely. The surgeon ensures that the median nerve is fully decompressed and that there are no remaining constrictive bands. It is usually an outpatient procedure done under local anesthesia.",[14],[30],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Sebastian Poggio Voormolen, BSc, PhD candidate","CONTACT","+31 6 46560865","PoggioVoormolenS@maasstadziekenhuis.nl",[36,61],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Maasstad Ziekenhuis","RECRUITING","Rotterdam","South Holland","3079 DZ","Netherlands","NL",{"type":45,"coordinates":46},"Point",[47,48],4.47917,51.9225,{"lat":48,"lon":47},[51,55,57,59],{"name":52,"role":32,"phone":53,"phoneExt":24,"email":54},"Niels W.L Schep, MD, PhD","+31 6 24232542","SchepN@maasstadziekenhuis.nl",{"name":31,"role":56,"phone":24,"phoneExt":24,"email":24},"SUB_INVESTIGATOR",{"name":58,"role":56,"phone":24,"phoneExt":24,"email":24},"Ileen Domela Nieuwenhuis Nyegaard, MD, PhD candidate",{"name":52,"role":60,"phone":24,"phoneExt":24,"email":24},"PRINCIPAL_INVESTIGATOR",{"facility":62,"status":38,"city":39,"state":40,"zip":63,"country":42,"countryCode":43,"cosmosGeoPoint":64,"geoPoint":66,"contacts":67},"Spijkenise Medisch Centrum","3201 GZ",{"type":45,"coordinates":65},[47,48],{"lat":48,"lon":47},[68,69,70,71],{"name":52,"role":32,"phone":53,"phoneExt":24,"email":54},{"name":31,"role":56,"phone":24,"phoneExt":24,"email":24},{"name":58,"role":56,"phone":24,"phoneExt":24,"email":24},{"name":52,"role":60,"phone":24,"phoneExt":24,"email":24},{"type":73,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100637823","mede-study-comparing-median-nerve-decompression-at-the-carpal-tunnel-alone-versus-median-nerve-decompression-at-both-the-carpal-tunnel-and-lacertus-fibrosis-in-adults-with-carpal-tunnel-syndrome-100637823",false,"NCT07594821","MeDe Study: Comparing Median Nerve Decompression at the Carpal Tunnel Alone Versus Median Nerve Decompression at Both the Carpal Tunnel and Lacertus Fibrosis in Adults With Carpal Tunnel Syndrome","MeDe Study: A Randomized Controlled Trial Comparing Median Nerve Decompression at the Carpal Tunnel Alone Versus Median Nerve Decompression at Both the Carpal Tunnel and Lacertus Fibrosis in Adults With Carpal Tunnel Syndrome","MeDe","Inclusion Criteria:\n\n* Patients being at least 18 years or older\n* CTS confirmed by EMG or nerve ultrasound\n* Patient opts for surgical treatment\n\nExclusion Criteria:\n\n* Previous surgical decompression of the median nerve at the ipsilateral wrist or forearm\n* Severe thenar atrophy: Examination of the thenar is based on clinical observation. The presence of thenar muscle atrophy is scored as none, mild, or severe.\n* Simultaneous nerve decompression in the ipsilateral arm (e.g. cubital tunnel, Guyon and radial nerve release.\n* Neurological disorders affecting peripheral nerves (e.g. spinal cord compression or injury, muscular dystrophy, dystonia, ALS)\n* Malunion of the distal radius\n* Impaired hand function\n* Pregnancy\n* Inability to complete study forms due to insufficient comprehension of the Dutch language","ALL","18 Years",{"count":85,"type":86},110,"ESTIMATED","INTERVENTIONAL",[89],"NA","Carpal tunnel syndrome (CTS) is a condition that can cause pain, numbness, or tingling in the hand and wrist. The most common surgery for CTS is called carpal tunnel release, which aims to relieve pressure on the main nerve in the wrist.\n\nHowever, after this surgery, some patients (up to 4 out of 10) still have symptoms, and about 1 in 8 may need another surgery. One reason symptoms can continue is that the nerve may also be compressed higher up in the arm, near a ligament called the Lacertus fibrosus. Releasing this area might help, but it is often not checked or treated during the first surgery because current tests (like physical exams, nerve studies, and ultrasounds) cannot reliably detect it.\n\nThis study is comparing two approaches for people with CTS:\n\n1. Standard surgery - only releasing the carpal tunnel.\n2. Extended surgery - releasing both the carpal tunnel and the Lacertus fibrosus.\n\nThe goal is to see which surgery helps patients feel better and have fewer symptoms in the hand and wrist after treatment.",[92,93],"Carpal Tunnel Syndrome (CTS)","Lacertus Syndrome",[95,96,97,98,99,9,100],"carpal tunnel syndrome","proximal median nerve compression","lacertus syndrome","double crush","nerve decompression","lacertus release.","2026-06-25",{"date":103,"type":104},"2026-06-26","ACTUAL",{"date":106,"type":104},"2026-05-06",{"date":108,"type":86},"2028-02",{"name":5,"class":6},2]