[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558593":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":33,"responsibleParty":70,"collaborators":10,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":10,"eligibilityCriteria":77,"healthyVolunteers":74,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":10,"studyType":84,"phases":10,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Loma Linda University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Surgical Patients Receiving Non-Depolarizing Neuromuscular Blockade",null,"Surgical patients having surgery that requires muscle relaxation with non-depolarizing neuromuscular blockers and monitoring of the depth of muscle blockade.The muscle response to nerve stimulation will be compared between the ulnar and median nerve.",[13],"Device: Neuromuscular Transmission Monitoring",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","Neuromuscular Transmission Monitoring","A neuromuscular transmission module connected to electrodes applied to the skin and positioned to provide stimulation of a single nerve and monitor the muscular response to nerve stimulation",[9],[21],{"name":22,"affiliation":5,"role":23},"Michael Benggon, MD","PRINCIPAL_INVESTIGATOR",[25,31],{"name":26,"role":27,"phone":28,"phoneExt":29,"email":30},"Melissa D McCabe, MD, MSCR","CONTACT","909 558 4475","44475","mmccabe@llu.edu",{"name":22,"role":27,"phone":28,"phoneExt":29,"email":32},"mbenggon@llu.edu",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Loma Linda University Troesch Medical Center","RECRUITING","Loma Linda","California","92354","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-117.26115,34.04835,{"lat":46,"lon":45},[49,52,57,59,62,64,66,67,68],{"name":50,"role":27,"phone":51,"phoneExt":10,"email":30},"Melissa M McCabe, MD","909-558-4475",{"name":53,"role":27,"phone":54,"phoneExt":55,"email":56},"Morgan E Blazy, BS","9095584227","44256","MBlazy@llu.edu",{"name":58,"role":23,"phone":10,"phoneExt":10,"email":10},"Melissa D McCabe, MD",{"name":60,"role":61,"phone":10,"phoneExt":10,"email":10},"Edgardo E Reynoso, BA","SUB_INVESTIGATOR",{"name":63,"role":61,"phone":10,"phoneExt":10,"email":10},"Richard L Applegate, MD",{"name":65,"role":61,"phone":10,"phoneExt":10,"email":10},"Lauren S Pineda, MS",{"name":53,"role":61,"phone":10,"phoneExt":10,"email":10},{"name":22,"role":61,"phone":10,"phoneExt":10,"email":10},{"name":69,"role":61,"phone":10,"phoneExt":10,"email":10},"Ryan Lauer, MD",{"type":71,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100558593","median-versus-ulnar-nerve-quantitative-electromyography-neuromuscular-blockade-monitoring-comparison-100558593",false,"NCT06553131","Median Versus Ulnar Nerve Quantitative Electromyography Neuromuscular Blockade Monitoring Comparison","Inclusion Criteria:\n\n* Adults 18 - 75 years of age who are able to provide consent\n* Scheduled for elective surgery requiring muscle relaxation, in a supine position under general anesthesia, with an anticipated duration of at least 1.5 hours\n\nExclusion Criteria:\n\n* Contraindication to rocuronium use\n* Comorbidities that may prolong the duration of neuromuscular blockade or alter pharmacodynamics and\u002For pharmacokinetics, such as:\n* Neuromuscular disease\n* Expected or known difficult airway\n* Rocuronium allergy\n* BMI \\\u003C 18.5 or \\> 40\n* History of adhesive allergy\n* Upper extremity weakness, limb deformity, or absence of all or part of an upper limb\n* Patients undergoing surgical procedures requiring cardiopulmonary bypass","ALL","18 Years","75 Years",{"count":82,"type":83},32,"ESTIMATED","OBSERVATIONAL","Medications used to relax the muscles are used during surgery. The amount of muscle relaxation can monitored with devices that stimulate a specific nerve and evaluate the muscle response. The response to, and recovery from, medications that relax the muscles are best described for a nerve in the arm called the ulnar nerve. The investigators believe that other nerves in the arm, such as the median nerve, could be used to monitor the amount of muscle relaxation. The purpose of this study is to compare the muscle response at two different nerve sites after giving medications to relax the muscles.\n\nThis study is going to measure the depth of muscle relaxation during surgery at two different sites. The muscle response to stimulation of the ulnar nerve (located in the arm) will be compared to the muscle response to stimulation of the median nerve (also located in the arm).",[87],"Neuromuscular Blockade",[89,87,90],"Median Nerve","Ulnar Nerve","2026-01-28",{"date":93,"type":94},"2026-01-30","ACTUAL",{"date":96,"type":94},"2024-12-26",{"date":98,"type":83},"2026-12",{"name":5,"class":6},1]